Nutritional and Metabolic Diseases

A collective term for nutritional disorders resulting from poor absorption or nutritional imbalance, and metabolic disorders resulting from defects in biosynthesis (anabolism) or breakdown (catabolism) of endogenous substances. MeSH definition

All other conditions 236

Metabolic Diseases7,034
Glucose Metabolism Disorders4,210
Diabetes3,680
Nutrition Disorders3,138
Overnutrition2,763
Overweight2,762
Obesity2,747
Type 2 Diabetes1,537
Synucleinopathies1,194
Parkinson's Disease1,116
Metabolism, Inborn Errors888
Hyperinsulinism680
Lipid Metabolism Disorders678
Proteostasis Deficiencies676
Insulin Resistance661
Type 1 Diabetes661
Diabetes Complications604
Dyslipidemias461
Brain Diseases, Metabolic406
TDP-43 Proteinopathies396
Diabetic Angiopathies375
Malnutrition365
Brain Diseases, Metabolic, Inborn346
Bone Diseases, Metabolic343
Metabolic Syndrome341
ALS320
Hyperlipidemias301
Diabetic Neuropathies297
Lipid Metabolism, Inborn Errors264
Lysosomal Storage Diseases262
Amyloidosis257
Hyperglycemia254
Osteoporosis239
Prediabetic State238
Diabetic Foot228
Pediatric Obesity224
Diabetes, Gestational213
Carbohydrate Metabolism, Inborn Errors195
Lysosomal Storage Diseases, Nervous System182
Obesity, Morbid177
Iron Metabolism Disorders157
Lipidoses157
Diabetic Retinopathy146
Glucose Intolerance142
Iron Deficiencies138
DNA Repair-Deficiency Disorders137
Sphingolipidoses137
Mitochondrial Diseases131
Calcium Metabolism Disorders128
Malabsorption Syndromes124
Avitaminosis123
Frontotemporal Lobar Degeneration122
Amino Acid Metabolism, Inborn Errors115
Frontotemporal Dementia112
Diabetic Nephropathies111
Hypercholesterolemia110
Amyloidosis, Familial108
Water-Electrolyte Imbalance106
Hypoglycemia105
Amyloid Neuropathies104
Amyloid Neuropathies, Familial102
Vitamin D Deficiency96
Acid-Base Imbalance93
Lewy Body Disease93
Multiple System Atrophy93
Acidosis89
Hyperlipoproteinemias84
Anemia, Iron-Deficiency83
Celiac Disease79
Gout77
Metal Metabolism, Inborn Errors76
Mucopolysaccharidoses75
Hyperlipoproteinemia Type II74
Immunoglobulin Light-chain Amyloidosis68
Colorectal Neoplasms, Hereditary Nonpolyposis67
Glycogen Storage Disease65
Calcinosis63
Fabry Disease57
Ketosis57
Hypertriglyceridemia50
Hepatic Encephalopathy49
Obesity, Abdominal47
Phenylketonurias45
Glycogen Storage Disease Type II44
Gaucher Disease41
Child Nutrition Disorders40
Hereditary Central Nervous System Demyelinating Diseases38
Friedreich Ataxia35
Hepatolenticular Degeneration35
Rickets34
Osteoporosis, Postmenopausal33
Amyloidosis, Hereditary, Transthyretin-Related32
Pick Disease of the Brain32
Urea Cycle Disorders, Inborn30
Adrenal Hyperplasia, Congenital29
Dehydration29
Mucopolysaccharidosis IV28
Peroxisomal Disorders28
Short Bowel Syndrome28
Hyperkalemia26
Mitochondrial Myopathies26
Lipodystrophy25
Prader-Willi Syndrome25
Severe Combined Immunodeficiency25
Fanconi Anemia22
Mucopolysaccharidosis II22
Neuronal Ceroid-Lipofuscinoses22
Albinism21
Hypophosphatemia21
Severe Acute Malnutrition21
Chronic Kidney Disease-Mineral and Bone Disorder20
Hypocalcemia20
Infant Nutrition Disorders20
Adrenoleukodystrophy19
Aortic Valve, Calcification of19
Ornithine Carbamoyltransferase Deficiency Disease19
Pregnancy in Obesity19
Mucopolysaccharidosis III18
Shy-Drager Syndrome18
Arthritis, Gouty17
Homozygous Familial Hypercholesterolemia17
Niemann-Pick Diseases17
Gangliosidoses16
Hyperoxaluria, Primary16
Hyponatremia16
Iron Overload15
Li-Fraumeni Syndrome15
Diabetic Ketoacidosis14
Hyperphosphatemia14
Vascular Calcification14
Cystinosis13
Hypophosphatasia13
Leukodystrophy, Globoid Cell13
Leukodystrophy, Metachromatic13
Mucopolysaccharidosis I13
Gangliosidoses, GM212
Mitochondrial Encephalomyopathies12
Optic Atrophy, Hereditary, Leber12
Parkinson Disease 4, Autosomal Dominant Lewy Body12
Primary hyperoxaluria type 112
Cerebral Amyloid Angiopathy11
Pseudohypoparathyroidism11
Rickets, Hypophosphatemic11
Calciphylaxis10
Diabetic Cardiomyopathies10
Familial Hypophosphatemic Rickets10
Glycogen Storage Disease Type I10
Hypercalcemia10
Hypophosphatemia, Familial10
Nephrocalcinosis10
Porphyrias10
Ataxia Telangiectasia9
Hyperhomocysteinemia9
Leigh Disease9
MELAS Syndrome9
Methylmalonic acidemia9
Primary Progressive Nonfluent Aphasia9
Propionic Acidemia9
Vitamin B 12 Deficiency9
Xanthomatosis9
Fanconi Syndrome8
Frontotemporal Dementia With Motor Neuron Disease8
Lipomatosis8
Mucopolysaccharidosis VI8
Niemann-Pick Disease, Type C8
Vitamin A Deficiency8
X-Linked Combined Immunodeficiency Diseases8
Acidosis, Lactic7
Adenine phosphoribosyltransferase deficiency7
Citrullinemia7
Congenital Hyperinsulinism7
Fanconi Anemia, Complementation Group D17
Gangliosidosis, GM17
Hyperargininemia7
Hypokalemia7
Lipodystrophy, Congenital Generalized7
Mucopolysaccharidosis VII7
Obesity, Metabolically Benign7
Pelizaeus-Merzbacher Disease7
Protein Deficiency7
Sandhoff Disease7
Acidosis, Respiratory6
alpha-Mannosidosis6
Chediak-Higashi Syndrome6
Cystinuria6
Dent Disease6
Hemochromatosis6
Homocystinuria6
Hyperlactatemia6
Lactose Intolerance6
Lipodystrophy, Familial Partial6
Lipodystrophy, Partial, Acquired6
Pyruvate Kinase Deficiency of Red Cells6
Severe combined immunodeficiency due to adenosine deaminase deficiency6
Tay-Sachs Disease6
VLCAD deficiency6
Albinism, Oculocutaneous5
Argininosuccinic Aciduria5
Barth Syndrome5
Cholesterol Ester Storage Disease5
Cockayne Syndrome5
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency5
Creatine deficiency, X-linked5
Hepatorenal form of glycogen storage disease5
Hyperbilirubinemia, Hereditary5
Hypolipoproteinemias5
Kwashiorkor5
Lynch Syndrome II5
Mucolipidoses5
Obesity Hypoventilation Syndrome5
Optic Atrophy, Autosomal Dominant5
Primary hyperoxaluria type 25
Pyruvate Dehydrogenase Complex Deficiency Disease5
Refeeding Syndrome5
Refsum Disease5
Shwachman-Diamond Syndrome5
Sucrase-isomaltase deficiency, congenital5
Wolfram Syndrome5
Wolman Disease5
Xanthomatosis, Cerebrotendinous5
Zellweger Syndrome5
Alexander Disease4
Aromatic amino acid decarboxylase deficiency4
Canavan Disease4
Fetal Macrosomia4
Glucosephosphate Dehydrogenase Deficiency4
Glycogen Storage Disease Type IIb4
Hypercholesterolemia, Autosomal Dominant, 34
Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome4
Inappropriate ADH Syndrome4
Medium chain acyl CoA dehydrogenase deficiency4
N-acetyl glutamate synthetase deficiency4
Oculocerebrorenal Syndrome4
Ophthalmoplegia, Chronic Progressive External4
Parkinson Disease, Familial, Type 14
Piebaldism4
Porphyria, Acute Intermittent4
Protein-Energy Malnutrition4
Protoporphyria, Erythropoietic4
Adult-onset citrullinemia type 23
Ascorbic Acid Deficiency3
Carbamoyl-Phosphate Synthase I Deficiency Disease3
Carnitine-Acylcarnitine Translocase Deficiency3
Cerebral Amyloid Angiopathy, Familial3
Chondrodysplasia Punctata, Rhizomelic3
Congenital Disorders of Glycosylation3
Coproporphyria, Hereditary3
Crigler-Najjar Syndrome3
Drug Metabolism, Poor, CYP2D6-Related3
Fabry Disease, Cardiac Variant3
Folic Acid Deficiency3
Galactosemias3
Glut1 Deficiency Syndrome3
Glutaric Acidemia I3
Glycogen Storage Disease IB3
Hermanski-Pudlak Syndrome3
Hyperlipoproteinemia Type III3
Hypoalphalipoproteinemias3
Kearns-Sayre Syndrome3
Leukoencephalopathy with Brainstem and Spinal Cord Involvement and Lactate Elevation3
Lynch syndrome I (site-specific colonic cancer)3
Menkes Kinky Hair Syndrome3
Multiple Sulfatase Deficiency Disease3
Neuropathy ataxia and retinitis pigmentosa3
Niemann-Pick Disease, Type A3
Progeria3
Trifunctional Protein Deficiency With Myopathy And Neuropathy3
Vitamin D Hydroxylation-Deficient Rickets, Type 1B3

Conditions with the most active trials

All other conditions 236

Subcategories