Disease landscape

Type 1 Diabetes clinical trials

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466 active trials 258 recruiting 23 Phase 3 292 sponsors 57 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 40 of 57 changes on 19 trials

2026-08-27
Trial terminated
Trial terminated: Stopped for futility.
Primary completion moved earlier: 2027-12 → 2026-06-24
Completion moved earlier: 2027-12 → 2026-06-24
NCT05018585 A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production… · Diamyd Medical AB · Phase 3
2026-09-04
Primary completion pushed: 2026-12-05 → 2027-11-05
Completion pushed: 2026-12-05 → 2027-12-05
NCT06984185 Early Detection of Type 1 Diabetes · Hospices Civils de Lyon
2026-09-03
Primary completion pushed: 2026-08-30 → 2026-12-30
Recruitment opened
Completion pushed: 2026-10-30 → 2027-01-30
NCT07498738 Making Diabetes Care Fit for Young Adults Living With Type 1 Diabetes: Observations… · Leiden University Medical Center
2026-09-02
Primary completion pushed: 2026-08-31 → 2027-08-31
Enrollment reopened
Completion pushed: 2026-08-31 → 2027-08-31
NCT05268250 Remedy to Diabetes Distress (R2D2): A Scalable Screen to Treat Program for School-age… · Nemours Children's Clinic
2026-08-28
Primary completion pushed: 2028-05 → 2029-02
Completion pushed: 2028-08 → 2030-02
NCT07325201 Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous… · HealthPartners Institute · Phase 2
2026-08-21
Primary completion pushed: 2025-11-30 → 2026-11-30
NCT05515939 Evaluating the InPen in Pediatric Type 1 Diabetes · Wayne State University
2026-08-19
Primary completion pushed: 2026-07-01 → 2027-07-01
NCT06057662 Personalized Comprehensive Diabetes Support for Children With Newly Diagnosed Type 1… · University of California, Davis
2026-08-18
Primary completion pushed: 2026-06-30 → 2026-10-30
Completion pushed: 2026-06-30 → 2026-10-30
NCT06640478 A 12-week Pilot Nutrition Intervention for Children With New Diagnosis of Stage 3 Type 1… · Milton S. Hershey Medical Center
2026-08-14
Primary completion pushed: 2026-06 → 2026-12
Enrollment closed, study ongoing
Completion pushed: 2026-06 → 2026-12
NCT07212790 REAL-Fam Feasibility Study for Youth Diabetes Management · University of North Carolina, Chapel Hill
2026-08-13
Primary completion pushed: 2026-08 → 2027-02
Completion pushed: 2026-08 → 2027-02
NCT07226583 Using a Personalized Decision Support Tool to Help People With Type 1 Diabetes Manage… · Stanford University
2026-08-13
Primary completion pushed: 2026-06 → 2026-12
Completion pushed: 2026-06 → 2026-12
NCT06908057 Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With… · AdventHealth Translational Research Institute
2026-08-25
Primary endpoint(s) modified
NCT07187531 SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression… · SAb Biotherapeutics, Inc. · Phase 2
2026-09-03
Primary endpoint(s) modified
Recruitment opened
Primary completion pushed: 2027-05-15 → 2027-07-15
NCT07282639 App-Based Certified Diabetes Education Therapy (AB-CDE) · Oregon Health and Science University
2026-08-28
Primary endpoint(s) modified
Trial completed
Results posted: 2026-08-27
Completion moved earlier: 2026-04-30 → 2025-12-21
NCT04506151 Sleep Optimization to Improve Glycemic Control in Adults With Type 1 Diabetes · University of Illinois at Chicago
2026-08-20
Primary endpoint(s) modified
NCT07325201 Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous… · HealthPartners Institute · Phase 2
2026-09-03
Enrollment closed, study ongoing
Trial sites reduced: 38 → 33 locations
NCT07228117 GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living… · Medtronic MiniMed, Inc.
2026-09-02
Trial completed
NCT06717451 PS230005 Control-IQ 1.5 Post-Approval Study · Tandem Diabetes Care, Inc.
2026-08-29
Reclassified as completed (was terminated)
NCT06152042 Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus · Biomea Fusion Inc. · Phase 2
2026-09-04
Recruitment opened
NCT07490964 Polycystic Ovary Syndrome in Type 1 Diabetes · Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
2026-08-11
Recruitment opened
NCT06820281 Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes · Victor Chang Cardiac Research Institute · Phase 2

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-26 NCT07787754 The Effect of Sea Buckthorn Extract in Patients With Type 1 Diabetes The First Affiliated Hospital of Guangzhou Medical University new
2026-08-25 NCT07785037 Omnipod 5 Implementation in Belgian Paediatric Diabetes Care Queen Fabiola Children's University Hospital new
2026-08-25 NCT07786064 Comparative Study of the Postprandial Glycemic Profile After Consumption of a High-fat… Konstantinos Makrilakis, MD new
2026-08-21 NCT07778147 Effects of Bedtime Snack Composition on Overnight Glucose in Children and Adolescents… Didem Güneş Kaya new
2026-08-17 NCT07769138 Implementation of Networked Continuous Glucose Monitoring With Telemetry Within the… Imperial College Healthcare NHS Trust new
2026-08-04 NCT07745244 Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System SiBionics, Co, Ltd new
2026-08-03 NCT07742306 Continuous Glucose Monitoring in High-Risk Children and Youth With Type 1 Diabetes in the… Life for a Child Program, Diabetes Australia new
2026-07-31 NCT07739342 Evaluating the Occurrence of DKA in People With Type I Diabetes Abbott Diabetes Care new
2026-07-24 NCT07726680 GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes Shifa International Hospital new
2026-07-16 NCT07706803 Screening For Social Determinants Of Health In Routine Diabetes Care University of California, Los Angeles new

Active trials by phase

Early Phase 1
13
Phase 1
16
Phase 1/2
11
Phase 2
42
Phase 2/3
8
Phase 3
15
Phase 4
12
Not charted: 349 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 466

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07427251 The Postprandial Hypo-Avoid Study Steno Diabetes Center Copenhagen Recruiting 2026-08-13
NCT07086443 Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy Sequence LifeScience, Inc. Recruiting 2026-05-19
NCT07293715 Permissive Versus Strict Intrapartum Glucose Management in Type 1 Diabetes (PRISM-T1D) Ohio State University Recruiting 2026-04-29
NCT07159282 A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single… Applied Biologics, LLC Recruiting 2026-02-11
NCT05641753 Cholesterol Lowering and Residual Risk in Diabetes, Type 1 NYU Langone Health Recruiting 2025-12-29
NCT06021145 Effectiveness of Empagliflozin Added to Automated Insulin Delivery (AID) Systems in… McGill University Health Centre/Research Institute of the McGill University Health Centre Recruiting 2024-08-09
NCT03463564 Insulin Pump vs Multiple Daily Injections of Insulin and Glyco-metabolic Control in Type… University of Campania Luigi Vanvitelli Recruiting 2018-03-15
NCT03878459 Dapagliflozin Plus Pioglitazone in T1DM The University of Texas Health Science Center at San Antonio Active, Not Recruiting 2026-07-29
NCT06922656 Can the Addition of Pioglitazone to SGLT2 Inhibitor in Type 1 Diabetic Patients Amplify… Dasman Diabetes Institute Not Yet Recruiting 2025-08-29
NCT06600776 Mealtime or Post-meal Dosing of URLi in Medtronic 780G Hybrid Closed Loop System Tel-Aviv Sourasky Medical Center Not Yet Recruiting 2024-09-24
NCT06532682 Efficacy of Dapagliflozin in Early Diabetic Nephropathy in Type 1 Diabetes The First Affiliated Hospital with Nanjing Medical University Active, Not Recruiting 2024-08-01
NCT04698330 Effects Of Berberine Plus Inulin On Diabetes Care in Patients With LADA Second Xiangya Hospital of Central South University Not Yet Recruiting 2022-02-25
Phase 3
NCT07088068 A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in… Sanofi Recruiting 2026-08-10
NCT06217302 Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and… Alessandro Doria Recruiting 2026-03-24
NCT06832410 An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1… Vertex Pharmaceuticals Incorporated Recruiting 2026-03-23
NCT07258394 Clinical Study for Dimethyl Fumarate in Preserving Islet β-Cell Function in Type 1… Nanjing Medical University Recruiting 2026-03-05
NCT06630585 GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes University of Bern Recruiting 2026-01-26
NCT06894784 A Clinical Trial to Evaluate The Effects of Semaglutide and Empagliflozin Combined to… McGill University Health Centre/Research Institute of the McGill University Health Centre Recruiting 2025-03-30
NCT06082063 Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes Steno Diabetes Center Copenhagen Recruiting 2025-01-10
NCT07670650 PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide… University of Florida Not Yet Recruiting 2026-06-26
NCT06914895 A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes… Eli Lilly and Company Active, Not Recruiting 2026-05-12
NCT00679042 Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at… CellTrans Inc. Active, Not Recruiting 2026-04-06
NCT06962280 A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity… Eli Lilly and Company Active, Not Recruiting 2026-02-17
NCT01320345 The Fenofibrate And Microvascular Events in Type 1 Diabetes Eye. University of Sydney Active, Not Recruiting 2026-01-20
NCT04583462 Impact of Metformin on Peripheral Arterial Calcification in Type 1 Diabetes Assistance Publique - Hôpitaux de Paris Active, Not Recruiting 2025-11-24
See all 466 active Type 1 Diabetes trials with filters →

Top sponsors by active trials in this area

University of Colorado, Denver (12) · Sanofi (9) · Second Xiangya Hospital of Central South University (7) · Steno Diabetes Center Copenhagen (7) · Institut de Recherches Cliniques de Montreal (6) · University of Aarhus (6) · University of California, San Diego (6) · Vanderbilt University Medical Center (6) · City of Hope Medical Center (5) · Insulet Corporation (5)

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