Disease landscape

Diabetes clinical trials

Get alerts when Diabetes trials change

3,024 active trials 1,561 recruiting 154 Phase 3 1,384 sponsors 434 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 59 of 434 changes on 20 trials

2026-08-27
Trial terminated
Trial terminated: Stopped for futility.
Primary completion moved earlier: 2027-12 → 2026-06-24
Completion moved earlier: 2027-12 → 2026-06-24
NCT05018585 A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production… · Diamyd Medical AB · Phase 3
2026-09-01
Trial terminated
Trial terminated: The study was suspended and during this time recruitment and study activities were halted. The study was ultimately ter...
Primary endpoint(s) modified
Enrollment reduced: 255 → 85 participants
Results posted: 2026-08-31
Primary completion confirmed: April 2025 (last estimated March 2026)
NCT04416269 Oral Anti Diabetic Agents in the Hospital · Emory University · Phase 4
2026-08-28
Trial terminated
Trial terminated: Funding was terminated for the study.
Enrollment reduced: 353 → 37 participants
Primary completion moved earlier: 2028-03-31 → 2026-05-19
Completion moved earlier: 2028-05-31 → 2026-06-19
NCT05884775 Novel Digital Patient-Reported Outcomes Tool for Diabetes Management · NYU Langone Health
2026-08-27
Withdrawn before enrolling
Trial withdrawn: No funding
Enrollment reduced: 100 → 0 participants
NCT06445270 Lifestyle Interventions to Improve Glycemic Parameters and Reduce Gestational Diabetes in… · Indiana University
2026-08-21
Withdrawn before enrolling
Trial withdrawn: Lack of resources
Enrollment reduced: 1000 → 0 participants
NCT06596330 Integration of a Trained Language Model to Improve Glycemic Control With the My Heart… · Stanford University
2026-09-02
Primary completion pushed: 2027-06-30 → 2027-12-31
Primary endpoint(s) modified
Interventions modified
Completion pushed: 2030-06-30 → 2031-12-31
Trial arms changed: 1 → 2
NCT04786262 A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type… · Vertex Pharmaceuticals Incorporated · Phase 3
2026-09-03
Primary completion pushed: 2026-08 → 2026-12
Enrollment increased: 78 → 114 participants
Interventions modified
Completion pushed: 2026-08 → 2026-12
Trial arms changed: 11 → 13
NCT07463196 A Study Investigating the Safety, Absorption, Elimination, and the Effect on the Immune… · AC Immune SA · Phase 1
2026-09-03
Primary completion pushed: 2026-06-30 → 2026-10-30
Completion pushed: 2027-06-30 → 2027-10-30
NCT05743244 Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1… · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Phase 2
2026-09-01
Primary completion pushed: 2026-09-03 → 2027-02
Completion pushed: 2026-09-03 → 2027-02
NCT07269847 Comparing a Healthy Beef-Centric Diet to a Healthy U.S.-Style Diet on Metabolic Health… · National Cattlemen's Beef Association, a contractor to the Beef Checkoff
2026-08-29
Primary completion pushed: 2026-07-22 → 2027-07-22
Completion pushed: 2026-12-31 → 2027-12-31
NCT06555952 MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors · Clinical Nutrition Research Center, Illinois Institute of Technology
2026-09-04
Primary completion pushed: 2026-12-31 → 2027-05-31
NCT07325838 Digital Self-Management Education and Support for Young Adults With Type 2 Diabetes… · Recep Turan
2026-08-21
Primary completion pushed: 2026-12-23 → 2027-04-16
Trial sites expanded: 45 → 48 locations
Completion pushed: 2027-01-07 → 2027-04-30
NCT07340320 A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus · Corxel Pharmaceuticals · Phase 2
2026-08-12
Primary completion pushed: 2026-08-04 → 2028-03-23
Completion moved earlier: 2028-08-31 → 2028-03-23
NCT07112339 A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels… · Novo Nordisk A/S · Phase 4
2026-08-22
Primary completion pushed: 2026-02 → 2026-09
Enrollment closed, study ongoing
Completion pushed: 2026-06 → 2027-01
NCT05822544 Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or… · OrsoBio, Inc · Phase 1
2026-09-05
Primary completion pushed: 2026-07-30 → 2026-10-30
Completion pushed: 2026-07-30 → 2026-10-30
NCT06208189 Is the Degree of Perceived Effort During Resistance Exercise Important for Improvements… · University of New Mexico
2026-09-05
Primary completion pushed: 2026-02-01 → 2027-02-15
Enrollment closed, study ongoing
Completion pushed: 2026-02-01 → 2027-03-01
NCT05741125 Improving Appetite Self-Regulation in African American Adults With Type 2 Diabetes · University of North Carolina, Chapel Hill
2026-09-01
Primary completion pushed: 2026-08 → 2027-01
Completion pushed: 2026-08 → 2027-01
NCT05051436 The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics · Philip Kern · Phase 4
2026-09-05
Primary completion pushed: 2027-09 → 2028-03
NCT05911256 A Community Health Worker/Pharmacist Team to Improve Blood Sugars in Diabetes Care Using… · University of Massachusetts, Worcester
2026-09-05
Primary completion pushed: 2026-06-30 → 2027-06-30
Sponsor changed: Ian J. Neeland, MD → University Hospitals Cleveland Medical Center
Completion pushed: 2026-06-30 → 2027-06-30
NCT05933174 Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes · University Hospitals Cleveland Medical Center
2026-09-04
Primary completion pushed: 2026-12-05 → 2027-11-05
Completion pushed: 2026-12-05 → 2027-12-05
NCT06984185 Early Detection of Type 1 Diabetes · Hospices Civils de Lyon

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-03 NCT07802327 PMCF Study of GX-01S CGM in Adults With Diabetes MicroTech Medical（Hangzhou）Co.,Ltd. new
2026-09-03 NCT07802561 Comparison of Metformin Versus Glyburide for Blood Sugar Control in Women With… Nishtar Medical University new Phase 4
2026-09-03 NCT07802262 Prenatal Exercise and Glucose Regulation University of Central Arkansas new
2026-09-03 NCT07802106 Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow… Universidade Sao Francisco new
2026-09-03 NCT07801131 ULTRASONOGRAPHIC EVALUATION OF TALAR CARTILAGE THICKNESS IN PATIENTS WITH DIABETIC… Istanbul Physical Medicine Rehabilitation Training and Research Hospital new
2026-09-02 NCT07799961 Arizona CEAL: Linking Social Care With Healthcare Systems to Address SDOH Sairam Parthasarathy new
2026-09-02 NCT07798960 Effects of Transcutaneous Photobiomodulation on Diabetic Foot Ulcers. University of Nove de Julho new Phase 2
2026-09-02 NCT07800468 Efficacy of Topical Lidocaine Gel vs. Oral Duloxetine for Painful Diabetic Peripheral… Wah Medical college , POF hospital new Phase 4
2026-08-31 NCT07794384 Effects of a Researcher-Designed Diabetes Self-Management App on Self-Management… Fu Jen Catholic University Hospital new
2026-08-28 NCT07793305 Precision Diabetes Education Guided by Diabetes Complication Risk Assessment Taiwanese Association of Diabetes Educators new

Active trials by phase

Early Phase 1
42
Phase 1
93
Phase 1/2
37
Phase 2
171
Phase 2/3
22
Phase 3
132
Phase 4
155
Not charted: 2,372 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 3,024

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07802561 Comparison of Metformin Versus Glyburide for Blood Sugar Control in Women With… Nishtar Medical University Recruiting 2026-09-03
NCT05051436 The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics Philip Kern Recruiting 2026-08-31
NCT07771010 The Effect of Empagliflozin and Metformin on Oxidative Capacity and Microvascular… University Medical Centre Ljubljana Recruiting 2026-08-18
NCT05305287 Quantifying Hepatic Mitochondrial Fluxes in Humans The University of Texas Health Science Center at San Antonio Recruiting 2026-08-17
NCT07427251 The Postprandial Hypo-Avoid Study Steno Diabetes Center Copenhagen Recruiting 2026-08-13
NCT03883412 Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in… University of Virginia Recruiting 2026-08-12
NCT07112339 A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels… Novo Nordisk A/S Recruiting 2026-08-11
NCT07228195 SGLT2i Therapy in Islet Transplantation (SIT) University of Minnesota Recruiting 2026-07-22
NCT07719894 Cilostazol and Aspirin for Cardiovascular Event Prevention in Patients With Type 2… Seoul National University Bundang Hospital Recruiting 2026-07-22
NCT07711171 Efficacy and Safety of Canagliflozin in the Treatment of Type 2 Diabetes With Mild… Fudan University Recruiting 2026-07-17
NCT06003153 GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at… Massachusetts General Hospital Recruiting 2026-07-08
NCT07307235 Efficacy and Safety of iGlarLixi Versus Standard of Care in a Real-world Adult China… Shanghai Zhongshan Hospital Recruiting 2026-07-07
NCT07017270 Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis Unity Health Toronto Recruiting 2026-06-26
NCT06445946 DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment… Ohio State University Recruiting 2026-06-25
NCT06699810 Modeling Ketosis-Prone Diabetes Remission Via Diverse Mechanisms of Glucotoxicity Emory University Recruiting 2026-06-15
NCT06291155 Mechanism of SGLT2 Inhibition in the Kidney University of Michigan Recruiting 2026-06-11
NCT07614230 SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue… Junjie Yang Recruiting 2026-05-29
NCT06478186 Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes University of Kansas Medical Center Recruiting 2026-05-28
NCT07086443 Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy Sequence LifeScience, Inc. Recruiting 2026-05-19
NCT07588438 Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay. Las Rías Medical Center Recruiting 2026-05-19
NCT07224893 Once-Daily vs Twice-Daily Insulin Glargine in Pregestational Diabetes Management Eastern Virginia Medical School Recruiting 2026-05-15
NCT07561541 Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients Texas Tech University Health Sciences Center, El Paso Recruiting 2026-05-08
NCT05365425 Choline Fenofibrate and Carotid Atherosclerosis in Patients With Type 2 Diabetes and… Seoul National University Bundang Hospital Recruiting 2026-05-05
NCT05365438 Atmeg (Atorvastatin and Omega-3 Combination) and Carotid Atherosclerosis in Patients With… Seoul National University Bundang Hospital Recruiting 2026-05-05
NCT06399835 Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis Seoul National University Bundang Hospital Recruiting 2026-05-05
See all 3,024 active Diabetes trials with filters →

Top sponsors by active trials in this area

Novo Nordisk A/S (29) · Assiut University (25) · Eli Lilly and Company (24) · University of Colorado, Denver (22) · University of Alabama at Birmingham (21) · Steno Diabetes Center Copenhagen (20) · Johns Hopkins University (18) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (18) · Medical College of Wisconsin (16) · National Taiwan University Hospital (16)

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