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Johns Hopkins University clinical trial pipeline

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380 active trials 241 recruiting 17 Phase 3 44 disease areas 85 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days showing 45 of 85 changes on 20 trials

2026-09-22
Withdrawn before enrolling
Trial withdrawn: Change in protocol due to requirement for IND
Primary completion confirmed: September 2026 (last estimated September 2028)
NCT06687655 Impact of Exogenous Ketones on Sleep Apnea · Phase 1/2
2026-09-22
Trial status changed: Enrolling by Invitation → Suspended
Recruitment suspended: Continuing to pursue additional funding to continue with the study
Primary completion pushed: 2026-09 → 2026-12
Final enrollment: 35 participants (planned 270)
Completion pushed: 2026-09 → 2026-12
NCT04453657 Tele-Wellness Supported App for Family Child Care Home Providers and Families to Promote…
2026-09-04
Trial status changed: Not Yet Recruiting → Terminated
Trial terminated: minimum subject accrual complete
Primary completion confirmed: December 2019 (last estimated March 2027)
NCT02998502 The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in…
2026-09-30
Primary completion pushed: 2026-09 → 2027-04
Completion pushed: 2026-12 → 2027-07
NCT04162938 Use of a Patient-Centered Electronic App to Increase ED Patient's Knowledge on HCV to…
2026-09-24
Primary completion pushed: 2026-09-30 → 2026-12-30
Completion pushed: 2026-09-30 → 2026-12-30
NCT05463289 ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
2026-09-24
Primary completion pushed: 2026-09 → 2027-06-30
Completion pushed: 2026-09 → 2027-06-30
NCT04543461 American Lung Association (ALA) Lung Health Cohort
2026-09-05
Primary completion pushed: 2026-12-31 → 2027-12-31
Completion pushed: 2027-08-10 → 2027-12-31
NCT07768267 Herbal Supplement (Biocidin REMOVE) for Bacterial Overgrowth in Irritable Bowel Syndrome · Phase 2
2026-09-04
Primary completion pushed: 2026-09-18 → 2027-02-18
Completion pushed: 2027-01-18 → 2027-06-18
NCT03843463 Escitalopram and Language Intervention for Subacute Aphasia · Phase 2
2026-09-05
Primary completion pushed: 2026-09-30 → 2027-06-30
Completion pushed: 2026-12-31 → 2027-09-30
NCT04123314 Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's… · Early Phase 1
2026-09-05
Primary completion pushed: 2026-09-30 → 2026-12-30
NCT06355414 Psilocybin in Chronic Low Back Pain and Depression · Phase 1
2026-09-05
Primary completion pushed: 2026-09-12 → 2026-12-30
NCT05546658 Effects of Psilocybin in Obsessive Compulsive Disorder · Early Phase 1
2026-09-04
Primary completion pushed: 2026-09 → 2027-09-01
Completion pushed: 2026-09 → 2027-09-01
NCT07603518 The Pharmacokinetics of a Hemp-Based Topical Product · Phase 1
2026-09-09
Primary completion pushed: 2026-09-30 → 2027-03-30
Completion pushed: 2026-09-30 → 2027-03-30
NCT05622344 StableEyes With Active Neurofeedback
2026-09-09
Primary completion pushed: 2026-09-30 → 2027-03-30
NCT06123611 Pediatric Trauma Centers RE-AIM at Gun Safety
2026-09-09
Primary completion pushed: 2027-04-30 → 2027-09-30
Completion pushed: 2027-04-30 → 2027-09-30
NCT07681726 Project HOPE (Hypertension Outreach Through Partnership and Engagement)
2026-09-05
Primary completion pushed: 2026-09 → 2027-09
Completion pushed: 2027-03 → 2028-03
NCT05653232 Prophylaxis With Direct-acting Antivirals for Kidney Transplantation From HCV-Infected…
2026-09-04
Primary completion pushed: 2026-09 → 2027-09
Completion pushed: 2026-12 → 2027-12
NCT04820387 Assessment of Remote Vital Signs for Telemedicine Applications
2026-09-04
Primary completion pushed: 2026-09-30 → 2027-08-30
Enrollment closed, study ongoing
Completion pushed: 2026-11-30 → 2027-08-30
NCT05613010 Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver…
2026-09-03
Primary completion pushed: 2026-08 → 2026-12
Completion pushed: 2026-08 → 2026-12
NCT07511179 Personalized Closed-Loop Brain Stimulation for Patients With Primary Progressive Aphasia
2026-10-02
Primary endpoint(s) modified
Trial completed
Results posted: 2026-10-01
Study completion confirmed: August 2025 (last estimated September 2026)
NCT04989790 Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for…

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-30 NCT07850102 Brain Imaging of DSP-2342 Phase 2 Not Yet Recruiting
2026-09-29 NCT07845552 Oral Food Challenge After One to Two Doses of Omalizumab Treatment for Food Allergy Phase 4 Not Yet Recruiting
2026-09-29 NCT07846189 Rhythmic Entrainment and Alertness in Lewy Body Dementia Not Yet Recruiting
2026-09-28 NCT07843706 Empowering Pain Psychology Access and Collaboration (EPPAC) to Improve Treatment… Not Yet Recruiting
2026-09-18 NCT07828613 Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower… Not Yet Recruiting
2026-09-16 NCT07823101 Imaging Assessment of Swallowing and Speech Muscles in Inclusion Body Myositis Recruiting
2026-09-15 NCT07819487 A Community Health Worker Service to Address Acute Care Utilization Among Young and… Not Yet Recruiting
2026-09-14 NCT07819318 C-Raven LDCT: Lung Cancer Screening Intervention Not Yet Recruiting
2026-09-04 NCT07805811 Testing Heart Failure Resilience Intervention for Caregivers (HEROIC) in Advanced Heart… Phase 2 Not Yet Recruiting

Active trials by phase

Early Phase 1
11
Phase 1
31
Phase 1/2
7
Phase 2
41
Phase 2/3
6
Phase 3
11
Phase 4
14
Not charted: 259 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 380

NCT IDTitleConditionStatusUpdated
Phase 4
NCT07362433 Trial of an AI-enabled Digital Stethoscope to Improve Antibiotic Stewardship Respiratory Infections in Children Recruiting 2026-06-08
NCT06434233 Opioid Use After Laparoscopic Salpingectomy Opioid Use Recruiting 2026-06-03
NCT06704594 Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake… Premenstrual Dysphoric Disorder (PMDD) Recruiting 2026-05-07
NCT07389590 Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis Multiple Sclerosis Recruiting 2026-05-06
NCT06116526 Dupilumab De-escalation in Pediatric Atopic Dermatitis Atopic Dermatitis Recruiting 2026-04-20
NCT05954559 High Relaxivity Contrast Agent for Cardiac MR in the Myocardial Scar Assessment Myocardial Fibrosis Recruiting 2026-04-13
NCT07247058 Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS) Mild Autonomous Cortisol Secretion (MACS) Recruiting 2026-03-05
NCT03935295 Dysport ® as an Adjunctive Treatment to Bracing in the Management of Adolescent… Adolescent Idiopathic Scoliosis Recruiting 2025-12-09
NCT05704036 Estrogen Supplementation and Bone Health in Women With CF Cystic Fibrosis Recruiting 2025-11-14
NCT04781972 Multimodal Brain Imaging of the Neural Effects of Methylphenidate in Patients With ADHD ADHD - Combined Type Recruiting 2025-10-16
NCT07845552 Oral Food Challenge After One to Two Doses of Omalizumab Treatment for Food Allergy Food Allergy Not Yet Recruiting 2026-09-29
NCT07631377 The LalelaLung Study: Digital Stethoscope Clinical Evaluation Pneumonia Not Yet Recruiting 2026-09-23
NCT07540000 The INTERvening for LUNG Health Trial Spirometry Not Yet Recruiting 2026-09-16
NCT07220356 C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics Tobacco Dependence Active, Not Recruiting 2026-07-06
Phase 3
NCT05836987 The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial… Atrial Fibrillation Recruiting 2026-09-30
NCT07228104 Adjuvant Steroid Outcomes in Idiopathic Subglottic Stenosis Idiopathic Subglottic Stenosis Recruiting 2026-09-23
NCT06497465 Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving… Tuberculosis Recruiting 2026-09-11
NCT06253715 Shortened Regimen for Drug-susceptible TB in Children Tuberculosis Recruiting 2026-07-24
NCT04274179 Ketogenic Diet for New-Onset Absence Epilepsy Absence Epilepsy Recruiting 2026-05-07
NCT05265299 Trial to Determine Effective Aspirin Dose in COPD Pulmonary Disease, Chronic Obstructive Recruiting 2026-03-16
NCT05252754 Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP… Post-ERCP Acute Pancreatitis Recruiting 2025-12-09
NCT06525571 Outcomes of High-risk Non-muscle Invasive Bladder Cancer Treated With Blue Light Resection Bladder Cancer Recruiting 2025-11-18
NCT02000089 The Cancer of the Pancreas Screening-5 CAPS5)Study Pancreas Cancer Recruiting 2025-10-09
NCT05532657 ACHIEVE Brain Health Follow-Up Study Aging Active, Not Recruiting 2026-07-21
NCT05537220 Oral N-acetylcysteine for Retinitis Pigmentosa Retinitis Pigmentosa Active, Not Recruiting 2026-06-15
See all 380 active Johns Hopkins University trials with filters →

Disease areas by active trials, top 10 of 44

Diabetes (18) · Stroke (18) · Obesity (14) · Hypertension (13) · Depression (10) · Alzheimer's Disease (8) · Heart Failure (7) · Dementia (6) · Type 2 Diabetes (6) · ALS (5)

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