117 trials changed in the last 30 days: 4 stopped, 51 with notable changes, 62 with minor changes only.
Trial terminated
Also in this update: Final enrollment: 3 participants — 3% of the 120 planned; Primary completion date changed from estimate of May 2029 to Oct 1, 2026
neuroloop GmbHNot applicable NCT06518915 Registry history of NCT06518915 on ClinicalTrials.gov (opens the registry)
Withdrawn before enrolling
Eurofarma Laboratorios S.A.Phase 3 NCT06608472 Registry history of NCT06608472 on ClinicalTrials.gov (opens the registry)
Trial status changed: Recruiting → Withdrawn
Also in this update: Primary completion date changed from estimate of Jul 2026 to Sep 17, 2026
Sarfez Pharmaceuticals, Inc.Phase 3 NCT07223502 Registry history of NCT07223502 on ClinicalTrials.gov (opens the registry)
Trial terminated
Also in this update: Primary completion date changed from estimate of Dec 2027 to Sep 9, 2026
Gossamer Bio USA, Inc.Phase 2 NCT04816604 Registry history of NCT04816604 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Sep 2026 to Dec 2028
Also in this update: Trial sites expanded: 43 → 46 locations
ReCor Medical, Inc.Not specified NCT06297291 Registry history of NCT06297291 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Dec 31, 2026 to Dec 31, 2031
National Institutes of Health Clinical Center (CC)Phase 2 NCT01712620 Registry history of NCT01712620 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Jul 16, 2027 to Mar 2028
Also in this update: Trial sites expanded: 3 → 32 locations; Study completion pushed from Aug 30, 2028 to Feb 2029; and 1 more change in the last 30 days
IRulya Therapeutics Inc.Phase 2 NCT05798923 Registry history of NCT05798923 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Jul 1, 2026 to Jul 1, 2027
Also in this update: Trial sites reduced: 29 → 23 locations; Study completion pushed from Sep 1, 2026 to Sep 30, 2027
E-Star BioTech, LLCPhase 2 NCT06343298 Registry history of NCT06343298 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Sep 23, 2025 to May 15, 2026
Also in this update: Trial completed
Bichedam Co., Ltd.Phase 1 NCT07282145 Registry history of NCT07282145 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Aug 2026 to Mar 31, 2027
Also in this update: Study completion pushed from Dec 2026 to Jun 2027
University of AlbertaPhase 2 NCT06570473 Registry history of NCT06570473 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from May 2026 to Dec 2026
Also in this update: Study completion pushed from Jun 2026 to Dec 2026
University of LjubljanaNot applicable NCT07048509 Registry history of NCT07048509 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Oct 31, 2026 to Oct 31, 2027
Also in this update: Study completion pushed from Feb 28, 2027 to Feb 28, 2028
Brigham and Women's HospitalPhase 4 NCT05030545 Registry history of NCT05030545 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Sep 2026 to Dec 2027
Also in this update: Study completion pushed from Dec 2026 to Dec 2028
Mayo ClinicNot applicable NCT04508049 Registry history of NCT04508049 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Jun 16, 2026 to Jun 16, 2028
Duke UniversityNot specified NCT06604650 Registry history of NCT06604650 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Sep 30, 2026 to Mar 31, 2027
University of New MexicoNot applicable NCT06451458 Registry history of NCT06451458 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Jun 1, 2025 to Sep 1, 2027
Also in this update: Enrollment closed, study ongoing; Study completion pushed from Jun 1, 2025 to Oct 1, 2027
Douglas SealsPhase 2 NCT03821623 Registry history of NCT03821623 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Oct 1, 2027 to Mar 30, 2028
Also in this update: Recruitment opened; Study completion moved earlier from Oct 1, 2030 to Mar 30, 2030
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Not specified NCT07208331 Registry history of NCT07208331 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Aug 2026 to Aug 2030
Also in this update: Sponsor changed: Russell Richardson to D. Walter Wray
D. Walter WrayPhase 1 NCT02966665 Registry history of NCT02966665 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Jul 1, 2027 to Jan 2028
Also in this update: Study completion pushed from Dec 1, 2027 to Jun 2028
The Cleveland ClinicNot applicable NCT07218198 Registry history of NCT07218198 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Sep 15, 2026 to Apr 15, 2027
Also in this update: Recruitment opened
McMaster UniversityNot applicable NCT07648498 Registry history of NCT07648498 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Tenax Therapeutics, Inc.Phase 3 NCT07288398 Registry history of NCT07288398 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Merck Sharp & Dohme LLCPhase 3 NCT07218029 Registry history of NCT07218029 on ClinicalTrials.gov (opens the registry)
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Innovent Biologics (Suzhou) Co. Ltd.Phase 2 NCT07352969 Registry history of NCT07352969 on ClinicalTrials.gov (opens the registry)
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Vincentage Pharma Co., LtdPhase 2 NCT07360275 Registry history of NCT07360275 on ClinicalTrials.gov (opens the registry)
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Innovent Biologics (Suzhou) Co. Ltd.Phase 1 NCT07556796 Registry history of NCT07556796 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Final enrollment: 200 participants (planned 225)
Eli Lilly and CompanyPhase 1 NCT06148272 Registry history of NCT06148272 on ClinicalTrials.gov (opens the registry)
Trial status changed: Enrolling by Invitation → Completed
Also in this update: Final enrollment: 29 participants (planned 40)
Virginia Commonwealth UniversityNot applicable NCT07075978 Registry history of NCT07075978 on ClinicalTrials.gov (opens the registry)
Trial status changed: Enrolling by Invitation → Active, Not Recruiting
Uniformed Services University of the Health SciencesNot specified NCT05971433 Registry history of NCT05971433 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Enrollment increased: 19331 → 22340 participants
OSF Healthcare SystemNot specified NCT05555095 Registry history of NCT05555095 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of May 2027 to Aug 12, 2026; Final enrollment: 382200 participants (planned 2000000)
Ouraring Inc.Not specified NCT07267871 Registry history of NCT07267871 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Jun 30, 2027 to Oct 30, 2027
Also in this update: Study completion pushed from Dec 31, 2029 to Apr 30, 2030
Medtronic VascularNot applicable NCT07115953 Registry history of NCT07115953 on ClinicalTrials.gov (opens the registry)
Trial completed
Samara State Medical UniversityNot applicable NCT05931003 Registry history of NCT05931003 on ClinicalTrials.gov (opens the registry)
Trial status changed: Enrolling by Invitation → Active, Not Recruiting
University of California, San FranciscoNot applicable NCT06113458 Registry history of NCT06113458 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Johns Hopkins UniversityNot applicable NCT05321368 Registry history of NCT05321368 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Apr 2026 to Sep 23, 2026
Sindh Institute of Cardiovascular DiseasesPhase 2/3 NCT07462260 Registry history of NCT07462260 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Study completion date changed from estimate of Jun 2026 to Dec 15, 2025
Brigham and Women's HospitalPhase 4 NCT04840342 Registry history of NCT04840342 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Dec 2026 to Jun 2027
Also in this update: Study completion pushed from Jul 1, 2028 to Jun 1, 2030
Gradient Denervation TechnologiesNot applicable NCT06052072 Registry history of NCT06052072 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Sep 2026 to Jul 17, 2026
Mayo ClinicNot applicable NCT05968859 Registry history of NCT05968859 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Final enrollment: 416 participants (planned 528)
University of Alabama at BirminghamNot applicable NCT05367544 Registry history of NCT05367544 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Jun 2026 to May 1, 2026; Final enrollment: 14 participants (planned 24)
University of Illinois at ChicagoNot applicable NCT06504914 Registry history of NCT06504914 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
University of Wisconsin, MadisonNot applicable NCT06444308 Registry history of NCT06444308 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Dec 31, 2026 to Sep 29, 2026; Final enrollment: 246587 participants (planned 100)
DejthidaNathaphongNot specified NCT07067632 Registry history of NCT07067632 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Tulane UniversityNot applicable NCT05183763 Registry history of NCT05183763 on ClinicalTrials.gov (opens the registry)
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Also in this update: Study completion pushed from Sep 30, 2026 to Dec 30, 2026; Primary completion date changed from estimate of Sep 30, 2026 to Aug 28, 2026
Stanford UniversityNot specified NCT06272318 Registry history of NCT06272318 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Mar 30, 2028 to Aug 28, 2026; Final enrollment: 44 participants (planned 120)
University of North Carolina, Chapel HillNot applicable NCT07126587 Registry history of NCT07126587 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Jun 1, 2026 to Jan 1, 2026
Erasmus Medical CenterNot applicable NCT04373902 Registry history of NCT04373902 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Yale UniversityNot applicable NCT06081010 Registry history of NCT06081010 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Oct 1, 2026 to Dec 31, 2026
Rush University Medical CenterNot applicable NCT06899750 Registry history of NCT06899750 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 36 → 44 locations
Liquidia Technologies, Inc.Phase 3 NCT07285655 Registry history of NCT07285655 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 26 → 39 locations
Insmed IncorporatedPhase 3 NCT07481981 Registry history of NCT07481981 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Sep 1, 2026 to Jan 1, 2027
Also in this update: Study completion pushed from Sep 1, 2027 to Oct 1, 2027
Malamo CountourisPhase 4 NCT06281665 Registry history of NCT06281665 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 5 → 9 locations
Verve Medical, IncNot applicable NCT07005050 Registry history of NCT07005050 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Sep 30, 2026 to Dec 30, 2026
Duke UniversityNot applicable NCT05459077 Registry history of NCT05459077 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Aug 2026 to Oct 2026
Tulane UniversityNot applicable NCT04797403 Registry history of NCT04797403 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Jun 2027 to Dec 2027
Tulane UniversityNot applicable NCT06880562 Registry history of NCT06880562 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Oct 2027 to Dec 2027
University of California, Los AngelesNot applicable NCT06359691 Registry history of NCT06359691 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 44 → 48 locations
Corcept TherapeuticsPhase 2 NCT03604198 Registry history of NCT03604198 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 24 → 34 locations
Also in this update: Trial arms changed: 2 → 4
Retension Pharmaceuticals. Inc.Phase 2 NCT07142356 Registry history of NCT07142356 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 37 → 40 locations
Tempus AINot applicable NCT06911632 Registry history of NCT06911632 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 13 → 16 locations
And 1 more change in the last 30 days
Pulnovo Medical, Inc.Not applicable NCT07214376 Registry history of NCT07214376 on ClinicalTrials.gov (opens the registry)
Start date moved earlier from Sep 22, 2025 to Sep 6, 2025
And 1 more change in the last 30 days
Alnylam PharmaceuticalsPhase 3 NCT07181109 Registry history of NCT07181109 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Aug 3, 2027 to May 15, 2028
BayerPhase 3 NCT02562235 Registry history of NCT02562235 on ClinicalTrials.gov (opens the registry)
Start date changed from estimate of Sep 25, 2026 to Sep 17, 2026
Merck Sharp & Dohme LLCPhase 2 NCT07646860 Registry history of NCT07646860 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Jul 27, 2026 to Jan 25, 2027
Also in this update: Primary completion date changed from estimate of Jul 27, 2026 to Mar 27, 2026
Institut National de la Santé Et de la Recherche Médicale, FranceNot applicable NCT07207226 Registry history of NCT07207226 on ClinicalTrials.gov (opens the registry)
Start date pushed from Oct 2026 to Nov 2026
Wake Forest University Health SciencesNot applicable NCT06593119 Registry history of NCT06593119 on ClinicalTrials.gov (opens the registry)
Start date pushed from Sep 15, 2026 to Sep 30, 2026
Novartis PharmaceuticalsNot specified NCT07465666 Registry history of NCT07465666 on ClinicalTrials.gov (opens the registry)
Start date changed from estimate of Sep 27, 2026 to Sep 18, 2026
National Heart, Lung, and Blood Institute (NHLBI)Phase 3 NCT07613099 Registry history of NCT07613099 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Jul 1, 2026 to Jul 1, 2027
University of PennsylvaniaNot applicable NCT05736484 Registry history of NCT05736484 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Jun 30, 2026 to Jun 30, 2027
The Cleveland ClinicNot applicable NCT03288025 Registry history of NCT03288025 on ClinicalTrials.gov (opens the registry)
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Huons Co., Ltd.Phase 1 NCT06618079 Registry history of NCT06618079 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Feb 2024); last known: Recruiting
BRAC UniversityPhase 1 NCT06258473 Registry history of NCT06258473 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Seoul National University HospitalNot applicable NCT06759844 Registry history of NCT06759844 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting
Saglik Bilimleri UniversitesiNot specified NCT06635616 Registry history of NCT06635616 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Bezmialem Vakif UniversityNot applicable NCT06612099 Registry history of NCT06612099 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Foundation University IslamabadNot applicable NCT06610006 Registry history of NCT06610006 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Lin HanNot applicable NCT06588127 Registry history of NCT06588127 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Russian Cardiology Research and Production CenterNot specified NCT06587074 Registry history of NCT06587074 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Aug 2024); last known: Recruiting
University of ChicagoNot applicable NCT06364358 Registry history of NCT06364358 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Annina VischerNot applicable NCT06132451 Registry history of NCT06132451 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Medical University of ViennaNot specified NCT06098300 Registry history of NCT06098300 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Dec 2023); last known: Recruiting
University of Sao Paulo General HospitalNot applicable NCT05611268 Registry history of NCT05611268 on ClinicalTrials.gov (opens the registry)
Changed
Registry verification sweep
Changed
Registry marked status Unknown (sponsor has not verified the record since Oct 2023); last known: Active, Not Recruiting
Hospital Universitario de FuenlabradaNot applicable NCT05334173 Registry history of NCT05334173 on ClinicalTrials.gov (opens the registry)
Changed
| First posted | Trial | Sponsor | Phase |
|---|---|---|---|
| 2026-10-19 | NCT07880990 Behaviour Change Wheel Intervention to Promote Healthy Behaviors in Adults With… | Fujian Medical University Union Hospital new | |
| 2026-10-16 | NCT07878728 Text Message Support to Help Adults With Newly Diagnosed High Blood Pressure Control… | GIFT University new | |
| 2026-10-16 | NCT07879144 Digital Nudges to Improve Heart Health Actions After Community Screening in Malaysia… | Cardiovascular Advancement and Research Excellence Institute new | |
| 2026-10-15 | NCT07876895 Monitoring the Effectiveness and Safety of Antihypertensive Therapy With a Fixed-Dose… | Bosnalijek D.D new | |
| 2026-10-14 | NCT07874191 Retinal and Choroidal Microcirculation in Preeclampsia: An OCTA Study | Muğla Sıtkı Koçman University new | |
| 2026-10-13 | NCT07871500 Oliceridine Versus Sufentanil for Blood Pressure Control During Anesthesia Induction in… | Xingguo Xu new | Phase 4 |
| 2026-10-06 | NCT07860437 Instructor Interpersonal Behaviours in Classical Pilates as a Pathway to Improve Blood… | Instituto Politécnico de Leiria new | |
| 2026-10-02 | NCT07855679 Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and… | Azienda Ospedaliero-Universitaria Careggi new | |
| 2026-10-02 | NCT07853625 Sacubitril/Valsartan Versus Valsartan Alone on Left Atrial Volume Index in Hypertensive… | University of Health Sciences Lahore new | |
| 2026-10-01 | NCT07851610 Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0) | IRCCS SYNLAB SDN new |
| Early Phase 1 | 19 | |
| Phase 1 | 51 | |
| Phase 1/2 | 22 | |
| Phase 2 | 86 | |
| Phase 2/3 | 7 | |
| Phase 3 | 76 | |
| Phase 4 | 72 |
University of Alabama at Birmingham (21) · Vanderbilt University Medical Center (19) · Johns Hopkins University (14) · Assiut University (13) · Assistance Publique - Hôpitaux de Paris (12) · China National Center for Cardiovascular Diseases (12) · Mayo Clinic (12) · Duke University (11) · University of Sao Paulo General Hospital (11) · Brigham and Women's Hospital (10)