Sponsor pipeline

Brigham and Women's Hospital clinical trial pipeline

Get alerts when Brigham and Women's Hospital's trials change

288 active trials 141 recruiting 9 Phase 3 52 disease areas 44 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days showing 37 of 44 changes on 20 trials

2026-10-02
Primary completion pushed: 2026-06-30 → 2026-12-30
NCT04537416 Fertility, Hypercoagulability, and Inflammation (FREYA) Registry
2026-10-02
Primary completion pushed: 2026-12-31 → 2030-12-31
Completion pushed: 2026-12-31 → 2030-12-31
NCT01293214 Vascularized Composite Allotransplantation for Multiple Extremity Amputations
2026-10-02
Primary completion pushed: 2027-07-01 → 2027-12-01
NCT07746154 Alpha Down Electroencephalography (EEG) Neurofeedback for Alcohol Use Disorder…
2026-10-01
Primary completion pushed: 2026-08-01 → 2027-12-01
Completion pushed: 2026-09-01 → 2028-12-01
NCT05132283 Urologic Lymphadenectomy in AMIGO
2026-09-30
Primary completion pushed: 2029-01 → 2029-07
NCT07349134 WELL-MPN: A Digital Lifestyle App for Patients With MPNs
2026-09-22
Primary completion pushed: 2027-12-01 → 2028-09-01
Recruitment opened
Completion pushed: 2027-12-01 → 2028-09-01
NCT07577661 Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep… · Phase 1/2
2026-09-19
Primary completion pushed: 2026-11-30 → 2027-07
Completion pushed: 2027-01-01 → 2028-07
NCT06968390 Accelerated TMS for Perinatal Depression
2026-09-17
Primary completion pushed: 2026-08-30 → 2027-08-30
Completion pushed: 2026-08-30 → 2027-08-30
NCT05838508 Effect of Physical Activity Pattern on Cardiometabolic Health
2026-09-30
Primary endpoint(s) modified
Sponsor changed: Dana-Farber Cancer Institute → Brigham and Women's Hospital
Results posted: 2026-09-29
Completion pushed: 2025-09-30 → 2027-09-30
NCT03075072 Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With…
2026-09-22
Primary endpoint(s) modified
NCT07489352 N-of-1 Trial to Promote Beta-Blocker Titration in Heart Failure
2026-10-01
Sponsor changed: Dana-Farber Cancer Institute → Brigham and Women's Hospital
Trial completed
Final enrollment: 7 participants (planned 10)
Study completion confirmed: August 2026 (last estimated December 2026)
NCT05899361 A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest
2026-10-01
Sponsor changed: Dana-Farber Cancer Institute → Brigham and Women's Hospital
NCT05715684 Patient-Centered Surgical Prehabilitation
2026-10-02
Trial completed
Study completion confirmed: December 2025 (last estimated June 2026)
NCT04840342 MR Antagonist and LSD1 · Phase 4
2026-10-01
Trial completed
Final enrollment: 261 participants (planned 300)
Study completion confirmed: November 2025 (last estimated August 2026)
NCT05389904 Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides…
2026-09-22
Trial completed
NCT07390110 Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart…
2026-09-17
Recruitment opened
NCT07724938 Combination Tonsillectomy and Hypoglossal Nerve Stimulation for OSA Patients With Lateral…
2026-09-16
Enrolling by invitation only
NCT07715695 Evaluation of a Scalable Educational Intervention for Adjustment and Coping to Vision Loss
2026-09-10
Enrollment closed, study ongoing
NCT04030507 Screening Magnetic Resonance Imaging of the Brain in Patients With Breast Cancer
2026-09-09
Recruitment opened
Primary completion confirmed: September 2026 (last estimated April 2026)
Completion pushed: 2026-09 → 2027-03
NCT05747755 Achieving Diagnostic Excellence Through Prevention and Teamwork
2026-09-17
Trial sites expanded: 2 → 9 locations
NCT07303816 Statins to Prevent Cancer Associated Blood Clots · Phase 4

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-22 NCT07832942 Beta-2 Adrenergic Receptor Polymorphic Variants: An Endotype of Salt Sensitive… Not Yet Recruiting
2026-09-21 NCT07831278 Training Independent Muscle Activation From a Common Source Recruiting
2026-09-17 NCT07825480 Activity Post Spinal Surgery Engagement Trial Not Yet Recruiting

Active trials by phase

Early Phase 1
7
Phase 1
13
Phase 1/2
13
Phase 2
34
Phase 2/3
1
Phase 3
8
Phase 4
18
Not charted: 194 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 288

NCT IDTitleConditionStatusUpdated
Phase 4
NCT07303816 Statins to Prevent Cancer Associated Blood Clots Venous Thromboembolism Recruiting 2026-09-16
NCT04667494 Ultrasound Therapy In Cardiac Amyloidosis Amyloidosis Cardiac Recruiting 2026-08-21
NCT05543694 ED90 of Epidural Bupivacaine With Lidocaine for the Initiation of Labor Analgesia Labor Pain Recruiting 2026-07-13
NCT06146842 ED90 of Bupivacaine After Lidocaine Test Dose With DPE and EPL Labor Pain Recruiting 2026-07-13
NCT07136415 Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia… Menopausal Women Recruiting 2026-06-08
NCT07323524 Dapagliflozin in Active Lupus Nephritis Lupus Nephritis (LN) Recruiting 2026-05-26
NCT05390892 PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes Type2Diabetes Recruiting 2026-04-13
NCT05593055 Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in… Hypertension Recruiting 2026-04-06
NCT07112183 Open Label Treprostinil Raynaud's Study Raynaud's Disease Recruiting 2026-03-24
NCT06099093 Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan Prostate Cancer Recruiting 2026-01-29
NCT07087106 Glucose Consumption in MS Using [F-18]FDG-PET Multiple Sclerosis Recruiting 2026-01-09
NCT05152888 The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk Stable Coronary Disease Recruiting 2025-11-04
NCT05030545 Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical… Primary Aldosteronism Recruiting 2025-02-07
NCT03105518 Predictors of Postoperative Pain Following Oocyte Retrieval for Assisted Reproduction Oocyte Retrieval Active, Not Recruiting 2026-07-29
NCT03935971 The Effects of Dupilumab on Allergic Contact Dermatitis Allergic Contact Dermatitis Active, Not Recruiting 2026-07-16
NCT06034821 Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan Acute Suicidal Depression (ASD) Enrolling by Invitation 2025-12-15
NCT06479187 PSMAtrack-tracking Changes in PSMA-PET During Initial Therapy for Metastatic… Metastatic Prostate Cancer Active, Not Recruiting 2025-11-05
NCT06794944 Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients… Inflammatory Bowel Disease (IBD) Not Yet Recruiting 2025-11-03
Phase 3
NCT07560306 [64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy Cardiac Amyloidosis Recruiting 2026-07-21
NCT07427043 Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES) Opioid Consumption, Postoperative Recruiting 2026-05-22
NCT03216525 Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced… Bladder Cancer Recruiting 2023-09-28
NCT07654296 Assessing Suzetrigine for Pain Reduction Following Ureteroscopic Surgery Opioid Consumption, Postoperative Not Yet Recruiting 2026-09-18
NCT01169259 Vitamin D and Omega-3 Trial (VITAL) Cancer Active, Not Recruiting 2026-07-30
NCT05619302 Molecular Imaging of Myocardial Fibrosis in Cardiac Amyloidosis Cardiac Amyloidosis Active, Not Recruiting 2026-07-06
NCT02178410 VITAL Rhythm Study Cardiovascular Disease Active, Not Recruiting 2025-10-07
See all 288 active Brigham and Women's Hospital trials with filters →

Disease areas by active trials, top 10 of 52

Obesity (13) · Prostate Cancer (10) · Diabetes (9) · Heart Failure (9) · Hypertension (9) · Lung Cancer (8) · Breast Cancer (7) · Asthma (6) · COPD (6) · Depression (6)

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