Disease landscape

Atrial Fibrillation clinical trials

Get alerts when Atrial Fibrillation trials change

946 active trials 485 recruiting 39 Phase 3 486 sponsors 128 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-16

What changed in the last 30 days showing 54 of 128 changes on 19 trials

2026-08-20
Recruitment suspended
Recruitment suspended: Enrollment has been temporarily suspended out of an abundance of caution and in close consultation with trial lead...
NCT05147792 The CONFORM Pivotal Trial · Conformal Medical, Inc
2026-09-16
Primary completion pushed: 2027-03-15 → 2029-09-15
Completion pushed: 2027-10-15 → 2030-01-15
NCT05115214 Safety and Performance of the Affera SpherePVI™ Multi-Ablation System to Treat Paroxysmal… · Medtronic Cardiac Ablation Solutions
2026-09-16
Primary completion pushed: 2027-03-15 → 2029-09-15
Completion pushed: 2027-10-15 → 2030-01-15
NCT05144503 Safety and Performance of the SpherePVI™ Catheter to Treat Paroxysmal Atrial Fibrillation · Medtronic Cardiac Ablation Solutions
2026-09-16
Primary completion pushed: 2026-08-31 → 2026-11-30
Completion pushed: 2026-08-31 → 2026-11-30
NCT07139314 Timing of Anticoagulation After Emergency Endovascular Therapy for Acute Ischemic Stroke… · Capital Medical University
2026-09-01
Primary completion pushed: 2026-05-30 → 2027-07-31
Enrollment closed, study ongoing
Trial sites reduced: 46 → 41 locations
Final enrollment: 353 participants (planned 440)
Completion pushed: 2026-06-30 → 2027-07-31
NCT06455098 A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With… · Biosense Webster, Inc.
2026-08-18
Primary completion pushed: 2027-09-30 → 2027-12-30
Completion pushed: 2028-04-30 → 2028-08-30
NCT07106970 PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II) · Boston Scientific Corporation
2026-09-10
Primary completion pushed: 2026-12-31 → 2027-06-15
Completion pushed: 2026-12-31 → 2027-07-01
NCT04956978 Shared Decision Making to Address Racial Disparities in Oral Anticoagulation in NVAF · Duke University
2026-09-04
Primary completion pushed: 2030-07 → 2030-12-31
Sponsor changed: Stanford University → VA Office of Research and Development
Interventions modified
Completion pushed: 2030-07 → 2031-12-31
NCT07741955 Empowering Veterans in Research Effectively Using Virtual Engagement Tools · VA Office of Research and Development
2026-09-01
Primary completion pushed: 2028-08-31 → 2030-12-31
Primary endpoint(s) modified
Completion pushed: 2028-11-30 → 2031-03-31
NCT05841056 Short Term Anti-aRrhythmic Therapy for Post-Operative AF in Cardiac Surgery Patients… · Population Health Research Institute · Phase 3
2026-09-16
Primary endpoint(s) modified
Phase changed: not specified → not applicable
Sponsor changed: [Redacted] → Biosense Webster, Inc.
Trial status changed: Withheld → Not Yet Recruiting
Enrollment changed: None → 2300
Interventions modified
Trial arms changed: 0 → 2
NCT07788989 A Study to Predict Atrial Fibrillation (AF) Burden in Participants With PAF and PsAF… · Biosense Webster, Inc.
2026-08-29
Primary completion pushed: 2026-06-30 → 2027-06-30
Completion pushed: 2026-12-31 → 2027-12-31
NCT04371055 Intensive Rhythm Monitoring to Decrease Ischemic Stroke and Systemic Embolism - the… · University of Leipzig
2026-08-25
Primary completion pushed: 2027-03-31 → 2028-03-31
Completion pushed: 2027-03-31 → 2028-03-31
NCT06938412 Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial… · Icahn School of Medicine at Mount Sinai
2026-08-21
Primary completion pushed: 2026-09 → 2027-09
Completion pushed: 2027-03 → 2028-09
NCT06511505 NOrthwestern Tempus AI-enaBLed Electrocardiography (NOTABLE) Trial · Northwestern University
2026-08-21
Primary completion pushed: 2022-03-04 → 2023-03-26
Enrollment reduced: 2500 → 2002 participants
Trial completed
Completion moved earlier: 2026-12-31 → 2023-05-26
NCT05773222 Efficacy and Safety of Apixaban in Korean Frail Atrial Fibrillation Patient · Seoul National University Hospital
2026-08-20
Primary completion pushed: 2025-08-03 → 2026-09
Primary endpoint(s) modified
Trial status changed: Unknown → Recruiting
Completion pushed: 2026-02-03 → 2027-03
NCT06511505 NOrthwestern Tempus AI-enaBLed Electrocardiography (NOTABLE) Trial · Northwestern University
2026-08-20
Primary endpoint(s) modified
NCT07116525 A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter · Biosense Webster, Inc.
2026-08-27
Enrollment reduced: 678 → 569 participants
Trial completed
Primary completion pushed: 2025-12-30 → 2026-03-19
NCT06436924 Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant… · Heart Rhythm Clinical and Research Solutions, LLC
2026-09-10
Recruitment opened
NCT07625215 A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial… · Bayer · Phase 2
2026-08-26
Recruitment opened
Trial sites expanded: 0 → 8 locations
NCT07626411 Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation · Regeneron Pharmaceuticals · Phase 3
2026-09-16
Recruitment opened
Trial sites expanded: 0 → 14 locations
NCT07405671 Flecainide Safety in Patients With Coronary Artery Disease and Atrial Fibrillation · Universitaire Ziekenhuizen KU Leuven · Phase 4

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-15 NCT07820631 First-in-Human Study of the Circle Safe System for Diaphragm Response Monitoring During… Circle Safe, Inc. new
2026-09-14 NCT07816744 Danish Trial of Weight Loss to Reduce Atrial Fibrillation Progression Axel Brandes new
2026-09-10 NCT07811934 Single-Use Spherical Pulsed Ablation Catheter for Paroxysmal Atrial Fibrillation Shanghai Shineyo Medical Co., Ltd. new
2026-09-10 NCT07811817 The Outcomes of Sympathetic Cardiac Denervation on Postoperative Atrial Fibrillation… Zagazig University new
2026-09-10 NCT07812935 Closed-Loop Stimulation in Left Bundle Branch Area Pacing Bartlomiej Wrobel new
2026-09-08 NCT07808307 Tele-Rehabilitation After Catheter Ablation in Patients With Atrial Fibrillation Hande Cörüt new
2026-09-02 NCT07799519 Finerenone After Catheter Ablation to Reduce Atrial Fibrillation Recurrence National Cheng-Kung University Hospital new Phase 2
2026-08-28 NCT07792239 Dose Escalation Study to Assess Safety, Tolerability, and Efficacy of Budiodarone… Xyra, LLC new Phase 2
2026-08-25 NCT07783919 Single-Shot Versus Focal Dual-Energy Pulsed Field-Based Ablation for Atrial Fibrillation Marien Hospital Herne new
2026-08-21 NCT07779369 Pulsed Field Ablation for Atrial Fibrillation Using the VARIPULSE™ Catheter Radboud University Medical Center new

Active trials by phase

Early Phase 1
4
Phase 1
3
Phase 1/2
4
Phase 2
16
Phase 2/3
6
Phase 3
33
Phase 4
67
Not charted: 813 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 946

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07405671 Flecainide Safety in Patients With Coronary Artery Disease and Atrial Fibrillation Universitaire Ziekenhuizen KU Leuven Recruiting 2026-09-15
NCT07776054 Clinical Impact of SGLT2 Inhibitor After DC Cardioversion in Persistent AF With HFpEF Samsung Medical Center Recruiting 2026-08-20
NCT07275697 Waiting on Atrial Fibrillation Intervention Therapy (WAIT) Study Emma Svennberg Recruiting 2026-08-10
NCT07753200 Net Clinical Benefit of Edoxaban Versus Apixaban in Patients With Atrial Fibrillation and… Samsung Medical Center Recruiting 2026-08-10
NCT07727681 Perioperative Statins to Prevent AFib After Lung Surgery Peking Union Medical College Hospital Recruiting 2026-07-28
NCT07287345 Colchicine's Effect on Inflammatory Markers Ayesha Ather Recruiting 2026-06-25
NCT06953726 Comparing the Safety and Efficacy of Apixaban and Rivaroxaban VA Office of Research and Development Recruiting 2026-06-22
NCT04695106 Dual Antithrombotic Therapy With Dabigatran and Ticagrelor in Patients With ACS and… Medical University of Gdansk Recruiting 2026-06-16
NCT07649109 The Clinical Outcomes and Therapeutic Effects in Patients With Cardiac Implantable… National Taiwan University Hospital Recruiting 2026-06-16
NCT04796714 AntiPlatelet theraPy stratEgy followiNg Left Atrial appenDAGe closurE University Hospital, Bordeaux Recruiting 2026-06-10
NCT06486792 Stroke Prevention In Ischemic Stroke With Covert Atrial Fibrillation Assistance Publique - Hôpitaux de Paris Recruiting 2026-06-05
NCT03862859 The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With… Nicholas Carlson Recruiting 2026-05-19
NCT06528262 Effect of Enavogliflozin on Recurrence of Atrial Fibrillation After Catheter Ablation Yonsei University Recruiting 2026-05-12
NCT05955365 Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing… Insel Gruppe AG, University Hospital Bern Recruiting 2026-05-08
NCT04642430 COmparison of Bleeding Risk Between Rivaroxaban and Apixaban in Patients With Atrial… Ottawa Hospital Research Institute Recruiting 2026-04-22
NCT06212674 Single-stage Pulmonary Vein Isolation Combined With Percutaneous Left Atrial Appendage… Medical University of Silesia Recruiting 2026-04-13
NCT07508618 Study on the Prevention of Atrial Fibrillation Recurrence After Ablation by Qidong Yixin… Sir Run Run Shaw Hospital Recruiting 2026-04-02
NCT03868150 Prevention of Postop Atrial Fibrillation Through Intraoperative Inducibility of Atrial… Stanford University Recruiting 2026-02-17
NCT05844501 Ondansetron for the Management of Atrial Fibrillation Indiana University Recruiting 2026-02-04
NCT03968393 Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial… Population Health Research Institute Recruiting 2026-01-12
NCT07273994 Evaluation of Two Different Regimens of the Antiarrhythmic Drug Amiodarone to Maintain… Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau Recruiting 2025-12-10
NCT05829317 Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically… Dr. Stephanie Sibley Recruiting 2025-09-22
NCT06798714 The Effect of Colchicine on the Occurrence of Atrial Fibrillation After Cardiac Surgery Tomsk Cardiology Research Institute Recruiting 2025-09-09
NCT02347111 Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation University of Illinois at Chicago Recruiting 2025-08-24
NCT07125417 Non-antithrombotic Versus. Single Antiplatelet Therapy Following Left Atrial Appendage… OCEAN-SHD Study Group Recruiting 2025-08-15
See all 946 active Atrial Fibrillation trials with filters →

Top sponsors by active trials in this area

Beijing Anzhen Hospital (22) · Yonsei University (20) · Boston Scientific Corporation (18) · China National Center for Cardiovascular Diseases (13) · Medtronic Cardiac Ablation Solutions (12) · National Taiwan University Hospital (11) · Biosense Webster, Inc. (10) · Ottawa Heart Institute Research Corporation (10) · Abbott Medical Devices (9) · Kansas City Heart Rhythm Research Foundation (9)

Get alerts when Atrial Fibrillation trials change
Status changes, date slips, and new sponsor entrants: detected daily, delivered to your inbox.
Start monitoring free