Disease landscape

Prostate Cancer clinical trials

Get alerts when Prostate Cancer trials change

1,916 active trials 1,082 recruiting 174 Phase 3 742 sponsors 262 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 50 of 262 changes on 20 trials

2026-09-03
Reclassified as terminated (was completed)
Trial terminated: Study completed
Results posted: 2026-09-02
NCT05700903 Contributions to Hypertension With Androgen Deprivation Therapy · University of Colorado, Denver · Phase 4
2026-08-28
Withdrawn before enrolling
Trial withdrawn: Other - Protocol moved to Withdrawn
Enrollment reduced: 24 → 0 participants
NCT06982222 Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have… · National Cancer Institute (NCI) · Phase 1
2026-08-14
Trial status changed: Completed → Terminated
Trial terminated: Accrual and drug manufacturing and supply were discontinued in 2025.
NCT02769962 Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With… · National Cancer Institute (NCI) · Phase 1/2
2026-08-29
Trial status changed: Recruiting → Withdrawn
Trial withdrawn: Due to funding issues the study did not move forward with prospective enrollment
NCT06804785 Hybrid Intelligence for Trustable Diagnosis and Patient Management of Prostate Cancer… · Northwestern University
2026-08-25
Trial terminated
Primary completion moved earlier: 2028-06-15 → 2026-07-15
Completion moved earlier: 2028-12-15 → 2026-07-31
NCT07068555 Prostate Cancer Vaccines · Shenzhen Geno-Immune Medical Institute · Phase 1/2
2026-08-21
Recruitment suspended
Recruitment suspended: Pending additional funding.
NCT06200103 Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate… · Mayo Clinic · Phase 2
2026-09-05
Primary completion pushed: 2026-10-08 → 2027-03-13
Completion pushed: 2028-12-02 → 2029-05-07
NCT06555796 Evaluation of Xaluritamig in High-Risk, Biochemically Recurrent, Non-metastatic… · Amgen · Phase 1
2026-09-05
Primary completion pushed: 2025-11-30 → 2026-11-01
Recruitment opened
Enrollment increased: 20 → 200 participants
Trial sites expanded: 0 → 3 locations
Completion pushed: 2026-01-10 → 2026-12-10
NCT06830265 Comparing Standard of Care Biopsy System to a Novel Biopsy Needle System by Computational… · Uro-1 Medical
2026-09-01
Primary completion pushed: 2025-08-31 → 2026-09
Interventions modified
Completion pushed: 2025-08-31 → 2026-09
Trial arms changed: 1 → 4
NCT05942001 Study of HRS-5041 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC) · Jiangsu HengRui Medicine Co., Ltd. · Phase 1
2026-08-27
Primary completion pushed: 2029-02-13 → 2029-06-04
Trial sites expanded: 104 → 132 locations
Completion pushed: 2029-12-20 → 2030-06-06
NCT07611110 AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant… · AstraZeneca · Phase 3
2026-08-15
Primary completion pushed: 2025-05-20 → 2026-01-21
Trial status changed: Unknown → Completed
Trial sites expanded: 1 → 8 locations
Completion pushed: 2025-05-20 → 2026-03-09
NCT06490328 Efficacy and Safety of DKF-MA102 in Patients With Prostate Cancer · Dongkook Pharmaceutical Co., Ltd. · Phase 3
2026-08-12
Primary completion pushed: 2026-07-13 → 2026-12-28
Trial sites reduced: 230 → 224 locations
NCT06551324 A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in… · Pfizer · Phase 3
2026-09-04
Primary completion pushed: 2026-09-30 → 2028-09-30
Completion pushed: 2026-09-30 → 2028-09-30
NCT01410942 Multimodal Therapy for the Treatment of Fatigue in Patients With Prostate Cancer… · M.D. Anderson Cancer Center · Phase 2
2026-08-15
Primary completion pushed: 2026-07-31 → 2026-10-31
Completion pushed: 2026-07-31 → 2026-10-31
NCT03436485 Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant… · Orion Corporation, Orion Pharma · Phase 1/2
2026-08-11
Primary completion pushed: 2028-06-15 → 2028-10-15
NCT07450599 A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy… · Bayer · Phase 2
2026-09-03
Primary completion pushed: 2026-08-04 → 2027-08-04
Completion pushed: 2026-08-04 → 2027-08-04
NCT04997018 A Study of MRI-guided High-dose Radiation Therapy in Prostate Cancer · Memorial Sloan Kettering Cancer Center · Phase 2
2026-09-01
Primary completion pushed: 2027-05-01 → 2028-02-28
Completion pushed: 2028-05-01 → 2028-08-31
NCT06600698 Safety and Efficacy of AGN-INM176 in Prostate Patients With Rising PSA · Milton S. Hershey Medical Center · Phase 1/2
2026-09-04
Primary completion pushed: 2028-08 → 2029-09
Completion pushed: 2028-08 → 2029-09
NCT07685249 Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment · Duke University
2026-09-02
Primary completion pushed: 2026-07-28 → 2027-06-28
Completion pushed: 2026-07-28 → 2027-06-28
NCT01923506 Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer After… · City of Hope Medical Center · Phase 1
2026-09-04
Primary completion pushed: 2026-09 → 2027-09
Completion pushed: 2027-01 → 2028-01
NCT06138067 Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-02 NCT07800390 proState Cancer Health Education to pRomote Early sreENing Uptake (SCREEN): A Pilot… Teesside University new
2026-08-28 NCT07793435 A Phase 1/2 Trial of ADI-212 in mCRPC Adicet Therapeutics new Phase 1/2
2026-08-24 NCT07781852 Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and… Lumina Pharmaceuticals Inc new Early Phase 1
2026-08-24 NCT07782112 Best Salvage Treatment for High-risk Relapsing Prostate Cancer (PEACE-9 - ESCALATE-RT) Ente Ospedaliero Cantonale, Bellinzona new Phase 3
2026-08-24 NCT07782164 Irreversible Electroporation (IRE) for Treating Recurrent Pelvic Tumors (PELFIRE Study) Amsterdam UMC, location VUmc new
2026-08-20 NCT07777263 ADT De-escalation in Selected High-Risk Prostate Cancer Patients (ADaPPt Trial) a GROUQ… Dr. Tamim Niazi new Phase 3
2026-08-14 NCT07766122 Analysis of the Performance of PSMA Emission Tomography in Patients With Prostate Cancer… University Hospital, Toulouse new Phase 4
2026-08-14 NCT07766603 Preoperative Breathing Exercise Training and Postoperative Delirium After Robotic Radical… ALİ DEMİRTAŞ new
2026-08-14 NCT07765940 Safety and Preliminary Diagnostic Performance of [⁶⁴Cu]Cu-RAX301 in Prostate Cancer RadAlliance Therapeutics, Inc new Phase 1/2
2026-08-11 NCT07757490 Sonablate HIFU International Registry for PC & BPH Patients Sonablate new

Active trials by phase

Early Phase 1
44
Phase 1
175
Phase 1/2
135
Phase 2
381
Phase 2/3
25
Phase 3
149
Phase 4
28
Not charted: 979 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 1,916

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07252726 Evaluating Dose Timing (Morning vs Evening) of Endocrine-based Therapies in Metastatic… Ottawa Hospital Research Institute Recruiting 2026-07-17
NCT05348876 A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real… Bayer Recruiting 2026-07-06
NCT05803941 Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate… Novartis Pharmaceuticals Recruiting 2026-06-04
NCT06733350 Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men… Roswell Park Cancer Institute Recruiting 2026-05-14
NCT06099093 Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan Brigham and Women's Hospital Recruiting 2026-01-29
NCT05919329 Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal… OHSU Knight Cancer Institute Recruiting 2025-10-24
NCT06908694 Investigation of GLP1-Receptor Agonists in Men With Prostate Cancer Taking Androgen… Hamilton Health Sciences Corporation Recruiting 2025-07-29
NCT07001709 Determining the Effect of Abiraterone on the Metabolism of Oxycodone in Men With Prostate… Deventer Ziekenhuis Recruiting 2025-06-03
NCT05805436 Preop Laxatives in Robotic Urologic Surgery Chad R. Tracy Recruiting 2025-05-30
NCT06784986 Impact of Using the Airseal System With Ultra-low Pneumoperitoneum in Patients Undergoing… Brazilian Institute of Robotic Surgery Recruiting 2025-01-20
NCT06706921 18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy… VA Greater Los Angeles Healthcare System Recruiting 2024-11-27
NCT05629494 Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test Albany Medical College Recruiting 2024-10-18
NCT06001619 Prostate Medication, Metabolism and Gut Microbiota Turku University Hospital Recruiting 2023-08-21
NCT07802847 Innovative and Cooperative Pathway Integrating Oncogeriatric, Pharmaceutical and… Gustave Roussy, Cancer Campus, Grand Paris Not Yet Recruiting 2026-09-03
NCT07766122 Analysis of the Performance of PSMA Emission Tomography in Patients With Prostate Cancer… University Hospital, Toulouse Not Yet Recruiting 2026-08-14
NCT07278362 Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under… University of Miami Not Yet Recruiting 2026-07-22
NCT04549207 Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients… Ottawa Hospital Research Institute Active, Not Recruiting 2026-07-21
NCT04597125 RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs… Bayer Active, Not Recruiting 2026-07-06
NCT07677566 177Lu-PSMA-617 Combined With Darolutamide in Neoadjuvant Treatment of High-risk Localized… The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Not Yet Recruiting 2026-07-01
NCT05722925 Evaluating Fluciclovine PET in Patients With Biochemical Recurrence of Prostate Cancer… OHSU Knight Cancer Institute Active, Not Recruiting 2026-06-29
NCT07569926 Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of… Blue Earth Diagnostics Not Yet Recruiting 2026-06-02
NCT05753046 Laparoscopic TAP Block During Robotic Assisted Laparoscopic Radical Prostatectomy for… Corewell Health East Enrolling by Invitation 2026-04-23
NCT05457257 Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With… AstraZeneca Active, Not Recruiting 2026-04-21
NCT03016741 Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer Northwestern University Active, Not Recruiting 2026-02-24
NCT06627530 COACTION Trial - COmbination Androgen bloCkade in inTermediate to hIgh-risk prOstate… Brazilian Clinical Research Institute Active, Not Recruiting 2026-02-11
See all 1,916 active Prostate Cancer trials with filters →

Top sponsors by active trials in this area

M.D. Anderson Cancer Center (41) · Memorial Sloan Kettering Cancer Center (40) · National Cancer Institute (NCI) (37) · Jonsson Comprehensive Cancer Center (29) · AstraZeneca (26) · Mayo Clinic (26) · University Health Network, Toronto (26) · Novartis Pharmaceuticals (25) · City of Hope Medical Center (21) · Chinese University of Hong Kong (20)

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