Sponsor Pipeline

AstraZeneca Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-07-07
506
Active Trials
246
Recruiting
168
Phase 3
10
Disease Areas
128
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-07-07 NCT07007793
A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary…
date change Primary completion moved earlier: 2028-02-18 -> 2027-08-13
2026-07-07 NCT07007793
A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary…
date change Completion pushed: 2028-02-18 -> 2028-08-14
2026-07-03 NCT07081646
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With…
Primary endpoint(s) modified
2026-07-03 NCT07343960
A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in…
date change Primary completion pushed: 2026-07-31 -> 2026-11-11
2026-07-03 NCT07343960
A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in…
date change Completion pushed: 2026-07-31 -> 2026-11-11
2026-07-03 NCT05775159
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents…
overall status: "Recruiting" → "Active Not Recruiting"
2026-07-03 NCT05775159
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents…
Trial sites reduced: 60 -> 46 locations
2026-07-03 NCT07000357
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of…
Trial sites expanded: 1333 -> 1365 locations
2026-07-03 NCT07201558
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE…
Trial sites expanded: 19 -> 33 locations
2026-07-03 NCT06008093
A Study to Investigate the Efficacy of Durvalumab Plus Tremelimumab in Combination With…
date change Primary completion moved earlier: 2026-12-08 -> 2026-10-23
2026-07-03 NCT06008093
A Study to Investigate the Efficacy of Durvalumab Plus Tremelimumab in Combination With…
date change Completion pushed: 2027-12-23 -> 2028-02-28
2026-07-03 NCT07024706
Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for…
Recruitment opened
2026-07-03 NCT07024706
Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for…
Trial sites expanded: 29 -> 36 locations
2026-07-03 NCT07024706
Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for…
date change Completion pushed: 2029-05-15 -> 2033-03-23
2026-07-03 NCT03330847
To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus…
date change Completion pushed: 2026-09-04 -> 2026-10-09
2026-07-03 NCT04504825
A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb…
Primary endpoint(s) modified
2026-07-03 NCT05460273
A Study of Dato-DXd in Chinese Patients With Advanced Non-Small Cell Lung Cancer…
date change Completion pushed: 2026-06-30 -> 2027-06-30
2026-07-03 NCT07017179
This is a Multi-centre, Multi-drug, Platform Study in Chinese Participants Living With…
overall status: "Recruiting" → "Active Not Recruiting"
2026-07-03 NCT07017179
This is a Multi-centre, Multi-drug, Platform Study in Chinese Participants Living With…
Enrollment reduced: 871 -> 14 participants
2026-07-02 NCT07024823
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of…
date change Primary completion pushed: 2026-06-18 -> 2026-12-25
Showing 20 of 128 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-07-06 NCT07685600 Investigating the Effect of Itraconazole on the Pharmacokinetics of AZD4144 in Healthy… Phase 1 Not Yet Recruiting
2026-07-02 NCT07681596 A Modular, Phase I/II, Multicentre Study to Evaluate AZD4045, in Participants With… Phase 1/2 Not Yet Recruiting
2026-06-29 NCT07674121 PROLONG (PRostateOLaparibONcombinationGcc) Study Not Yet Recruiting
2026-06-25 NCT07667803 A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With… Phase 3 Not Yet Recruiting
2026-06-24 NCT07664553 A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With… Phase 3 Not Yet Recruiting
2026-06-23 NCT07662044 A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in… Phase 3 Not Yet Recruiting
2026-06-23 NCT07662109 A Phase III Study to Investigate the Efficacy and Safety of the Combination of… Phase 3 Not Yet Recruiting
2026-06-23 NCT07662135 A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With… Phase 3 Not Yet Recruiting
2026-06-23 NCT07662213 A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes… Phase 3 Not Yet Recruiting
2026-06-23 NCT07663409 The DEBATE Study "DEvelopment of Endotype-based Biomarkers for the Monitoring of Greek… Not Yet Recruiting
Active Trials by Phase
Phase 4
13
Phase 3
166
Phase 2/3
2
Phase 2
71
Phase 1/2
46
Phase 1
60
Not specified
148
Active Trials — top 25 of 506
NCT IDTitleConditionStatus
Phase 4
NCT07306949 Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association… Transthyretin-type Cardiac Amyloidosis Recruiting
NCT07221838 A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia… Generalized Myasthenia Gravis Recruiting
NCT06531798 Post-marketing Phase 4 Safety & Tolerability Study of Breztri aerosphereTM in Indian… Moderate to Severe COPD Recruiting
NCT07308574 Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS aHUS Recruiting
NCT07279935 Osimertinib Combined With Chemotherapy in Patients Who Had Distant Recurrence After… Non-small Cell Lung Cancer Recruiting
NCT06651970 Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL… Chronic Lymphocytic Leukaemia Recruiting
NCT06594068 Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in… Systemic Lupus Erythematosus Recruiting
NCT07073950 A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate… Chronic Obstructive Pulmonary Disease Recruiting
NCT07357597 An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd)… Stomatitis Not Yet Recruiting
NCT06610526 A Study of Dapagliflozin in Chinese Adult Patients With Chronic Kidney Disease Chronic Kidney Disease Active, Not Recruiting
NCT06422689 Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on… Asthma Active, Not Recruiting
NCT05457257 Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With… Metastatic Castration-resistant Prostate Cancer Active, Not Recruiting
NCT03953300 Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics Asthma Active, Not Recruiting
Phase 3
NCT07218809 AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low… Epithelial Ovarian Cancer Recruiting
NCT07024563 Study of Ravulizumab in Pediatric Participants With Primary IgAN IgAN Recruiting
NCT06607627 PK, PD, Safety, and Efficacy Study of Gefurulimab in Pediatric Patients With AChR+… Generalized Myasthenia Gravis Recruiting
NCT06350097 Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab… Non-small Cell Lung Cancer Recruiting
NCT07205822 A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0… Breast Cancer Recruiting
NCT06750289 Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as… Eosinophilic Asthma Recruiting
NCT06417814 A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib… Metastatic Non-small Cell Lung Cancer Recruiting
NCT06868277 A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line… Carcinoma, Non-Small Cell Lung Recruiting
NCT06471257 A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic… Asthma Recruiting
NCT06677060 Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in… Heart Failure Recruiting
NCT06455449 A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as… Polymyositis, Dermatomyositis Recruiting
NCT05692180 A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled… Asthma Recruiting
View all 506 active AstraZeneca trials with filters →
Disease Areas
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