Also listed under Liver Diseases
ClinicalTrials.gov term: Liver Neoplasms
80 trials changed in the last 30 days: 4 stopped, 31 with notable changes, 45 with minor changes only.
Trial status changed: Recruiting → Withdrawn
Also in this update: Study completion moved earlier from Dec 30, 2026 to Aug 14, 2026
TCM Biotech International Corp.Phase 1/2 NCT03812874 Registry history of NCT03812874 on ClinicalTrials.gov (opens the registry)
Recruitment suspended
Shandong Cancer Hospital and InstitutePhase 2 NCT07274774 Registry history of NCT07274774 on ClinicalTrials.gov (opens the registry)
Trial terminated
Also in this update: Primary completion date changed from estimate of Dec 31, 2025 to Oct 2, 2026; Final enrollment: 23 participants (planned 60)
Taichung Tzu Chi HospitalNot applicable NCT07178093 Registry history of NCT07178093 on ClinicalTrials.gov (opens the registry)
Trial status changed: Active, Not Recruiting → Suspended
Also in this update: Primary and study completion pushed from Jun 2026 to Mar 2027
Weill Medical College of Cornell UniversityNot applicable NCT03623464 Registry history of NCT03623464 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Oct 27, 2026 to Oct 27, 2028
Also in this update: Study completion pushed from Jan 27, 2028 to Jan 27, 2030
Inova Health Care ServicesPhase 2 NCT06789757 Registry history of NCT06789757 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Oct 2027 to Jun 2028
Also in this update: Study completion pushed from Jul 2028 to Dec 2028
Base Therapeutics (Shanghai) Co., Ltd.Early Phase 1 NCT07657416 Registry history of NCT07657416 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Oct 31, 2025 to Mar 29, 2027
Also in this update: Enrollment closed, study ongoing; Study completion pushed from Oct 31, 2026 to May 31, 2027
TORL Biotherapeutics, LLCPhase 1 NCT06005740 Registry history of NCT06005740 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Aug 2026 to Mar 2027
University of Michigan Rogel Cancer CenterPhase 2 NCT05901519 Registry history of NCT05901519 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Feb 28, 2029 to Dec 30, 2029
AstraZenecaNot specified NCT06544629 Registry history of NCT06544629 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Jul 1, 2026 to Jul 1, 2027
Mohamed Abdel-RahmanNot specified NCT04792463 Registry history of NCT04792463 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Dec 31, 2026 to Dec 31, 2027
National Cancer Institute (NCI)Phase 2 NCT02465060 Registry history of NCT02465060 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Dec 19, 2026 to Dec 19, 2028
Massachusetts General HospitalNot specified NCT06265272 Registry history of NCT06265272 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Nov 2026 to Nov 2028
Also in this update: Enrollment reopened; Enrollment increased: 51 → 80 participants
Memorial Sloan Kettering Cancer CenterNot specified NCT03432806 Registry history of NCT03432806 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Dec 1, 2024 to Dec 31, 2028
Also in this update: Enrollment closed, study ongoing; Study completion pushed from Dec 1, 2026 to Dec 31, 2028
The University of Hong KongPhase 2 NCT04988945 Registry history of NCT04988945 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Jun 30, 2026 to Mar 31, 2027
Also in this update: Study completion pushed from Sep 30, 2026 to Jun 30, 2027
Massachusetts General HospitalNot applicable NCT06541990 Registry history of NCT06541990 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Jul 2026 to Jul 2027
Also in this update: Recruitment opened; Study completion pushed from Dec 2026 to Dec 2027
Medical University of GrazNot specified NCT07341321 Registry history of NCT07341321 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Sep 2027 to Sep 2031
Centre Hospitalier Universitaire DijonNot specified NCT06600295 Registry history of NCT06600295 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Mar 15, 2027 to Dec 15, 2027
Also in this update: Enrollment reduced: 300 → 270 participants; Interventions modified
Nanjing Tianyinshan HospitalNot applicable NCT06893887 Registry history of NCT06893887 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Dec 31, 2025 to Dec 31, 2034
Also in this update: Study completion pushed from Dec 31, 2030 to Dec 31, 2039
Francesco De CobelliNot specified NCT03981497 Registry history of NCT03981497 on ClinicalTrials.gov (opens the registry)
Primary endpoint(s) modified
Also in this update: Results posted: Sep 29, 2026; Primary completion date changed from estimate of Jun 30, 2021 to Apr 14, 2022
Abivax S.A.Phase 1/2 NCT03897543 Registry history of NCT03897543 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Shanghai AbelZeta Ltd.Phase 1/2 NCT06590246 Registry history of NCT06590246 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Study completion date changed from estimate of May 31, 2027 to Jul 27, 2026
AstraZenecaPhase 3 NCT03847428 Registry history of NCT03847428 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Grey Wolf TherapeuticsPhase 1/2 NCT06923761 Registry history of NCT06923761 on ClinicalTrials.gov (opens the registry)
Trial status changed: Recruiting → Enrolling by Invitation
Also in this update: Study completion pushed from Oct 31, 2027 to Oct 31, 2028
The Methodist Hospital Research InstitutePhase 4 NCT05185505 Registry history of NCT05185505 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Study completion moved earlier from Dec 2028 to Dec 2027; Primary completion date changed from estimate of Dec 2026 to Aug 20, 2026
Georgetown UniversityPhase 3 NCT05482516 Registry history of NCT05482516 on ClinicalTrials.gov (opens the registry)
Enrollment increased: 285 → 330 participants
ModeX Therapeutics, An OPKO Health CompanyPhase 1/2 NCT06239194 Registry history of NCT06239194 on ClinicalTrials.gov (opens the registry)
Trial status changed: Enrolling by Invitation → Completed
Also in this update: Primary completion date changed from estimate of Jun 30, 2026 to Sep 30, 2025; Final enrollment: 5 participants (planned 50)
The Methodist Hospital Research InstitutePhase 2 NCT05171335 Registry history of NCT05171335 on ClinicalTrials.gov (opens the registry)
Sponsor refiled this as active, not recruiting (was completed)
Icahn School of Medicine at Mount SinaiPhase 2 NCT04123379 Registry history of NCT04123379 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Feb 1, 2029 to Jun 1, 2029
Also in this update: Study completion pushed from Feb 1, 2030 to Jun 1, 2030
University of California, San FranciscoPhase 2 NCT07682454 Registry history of NCT07682454 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Study completion date changed from estimate of Sep 30, 2025 to May 28, 2025; Primary completion moved earlier from Dec 31, 2024 to Aug 28, 2024
Xiangya Hospital of Central South UniversityNot specified NCT05932836 Registry history of NCT05932836 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Sep 30, 2026 to Dec 30, 2026
West China HospitalPhase 1 NCT07053072 Registry history of NCT07053072 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 219 → 226 locations
AstraZenecaPhase 3 NCT06921785 Registry history of NCT06921785 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from May 31, 2030 to Aug 31, 2030
Also in this update: Study completion moved earlier from Feb 28, 2031 to Aug 31, 2030
Mayo ClinicPhase 1/2 NCT03942328 Registry history of NCT03942328 on ClinicalTrials.gov (opens the registry)
Enrollment increased: 100 → 140 participants
Zymeworks BC Inc.Phase 1 NCT07164313 Registry history of NCT07164313 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Dec 31, 2026 to May 1, 2027
Mayo ClinicPhase 2 NCT06265285 Registry history of NCT06265285 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Dec 18, 2026 to May 15, 2027
Mayo ClinicPhase 2 NCT07285044 Registry history of NCT07285044 on ClinicalTrials.gov (opens the registry)
Enrollment increased: 100 → 125 participants
Tyra Biosciences, IncPhase 1 NCT06915753 Registry history of NCT06915753 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from May 25, 2028 to Oct 15, 2028
Also in this update: Trial sites expanded: 4 → 7 locations; Study completion pushed from May 25, 2029 to Oct 15, 2029
Zhejiang UniversityNot applicable NCT07596134 Registry history of NCT07596134 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Aug 31, 2026 to Nov 15, 2026
Fondazione Policlinico Universitario Agostino Gemelli IRCCSNot applicable NCT06929845 Registry history of NCT06929845 on ClinicalTrials.gov (opens the registry)
Trial sites reduced: 59 → 54 locations
Genentech, Inc.Phase 2 NCT06096779 Registry history of NCT06096779 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 54 → 58 locations
PfizerPhase 1/2 NCT07227012 Registry history of NCT07227012 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 14 → 23 locations
CatalYm GmbHPhase 2 NCT07219459 Registry history of NCT07219459 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 5 → 8 locations
Compass TherapeuticsPhase 1 NCT07419841 Registry history of NCT07419841 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 16 → 24 locations
AstraZenecaNot specified NCT07607769 Registry history of NCT07607769 on ClinicalTrials.gov (opens the registry)
Interventions modified
Suzhou Suncadia Biopharmaceuticals Co., Ltd.Phase 3 NCT07691762 Registry history of NCT07691762 on ClinicalTrials.gov (opens the registry)
Interventions modified
Suzhou Suncadia Biopharmaceuticals Co., Ltd.Phase 3 NCT06618664 Registry history of NCT06618664 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 18 → 23 locations
Alliance for Clinical Trials in OncologyNot applicable NCT07059884 Registry history of NCT07059884 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Jul 1, 2026 to May 27, 2027
AstraZenecaPhase 2 NCT06040099 Registry history of NCT06040099 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Oct 2, 2026 to Sep 1, 2027
City of Hope Medical CenterPhase 1 NCT02432963 Registry history of NCT02432963 on ClinicalTrials.gov (opens the registry)
Interventions modified
ExelixisPhase 1 NCT05176483 Registry history of NCT05176483 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Oct 31, 2026 to Oct 31, 2027
M.D. Anderson Cancer CenterPhase 2 NCT04083378 Registry history of NCT04083378 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Oct 31, 2026 to Sep 3, 2027
National Cancer Institute (NCI)Phase 2 NCT04175912 Registry history of NCT04175912 on ClinicalTrials.gov (opens the registry)
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
SCG Cell Therapy Pte. Ltd.Phase 1 NCT06617000 Registry history of NCT06617000 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Chugai PharmaceuticalPhase 1 NCT05022927 Registry history of NCT05022927 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
CNBG-Virogin Biotech (Shanghai) Ltd.Phase 1 NCT04806464 Registry history of NCT04806464 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Dec 2022); last known: Recruiting
Sun Yat-sen UniversityPhase 3 NCT05476432 Registry history of NCT05476432 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting
Ain Shams UniversityPhase 4 NCT06464380 Registry history of NCT06464380 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2022); last known: Not Yet Recruiting
National Taiwan University HospitalPhase 1/2 NCT05286320 Registry history of NCT05286320 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Apr 2024); last known: Not Yet Recruiting
Beijing 302 HospitalPhase 1 NCT06364787 Registry history of NCT06364787 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Apr 2024); last known: Not Yet Recruiting
Beijing 302 HospitalEarly Phase 1 NCT06364800 Registry history of NCT06364800 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Chang Gung Memorial HospitalNot specified NCT06628661 Registry history of NCT06628661 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting
Pak Emirates Military HospitalNot applicable NCT06602986 Registry history of NCT06602986 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Zhongda HospitalNot applicable NCT06593964 Registry history of NCT06593964 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Fudan UniversityNot applicable NCT06588569 Registry history of NCT06588569 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Sun Yat-sen UniversityNot applicable NCT06061276 Registry history of NCT06061276 on ClinicalTrials.gov (opens the registry)
Changed
Registry verification sweep
Changed
| First posted | Trial | Sponsor | Phase |
|---|---|---|---|
| 2026-10-13 | NCT07872319 Biomarkers Usefulness in the Screening of Hepatocellular Carcinoma in an European… | Hospital Universitario La Paz new | |
| 2026-10-06 | NCT07861425 Phase 1 Trial of ACE723, A Dual-Payload Antibody Drug Conjugate, in Patients With… | Acepodia Biotech, Inc. new | Phase 1 |
| 2026-09-30 | NCT07848750 InstaSure™ Non-Invasive Finger-Press Test for Hepatocellular Carcinoma | Beijing Municipal Administration of Hospitals new | |
| 2026-09-30 | NCT07850882 A Prospective Real-World Observational Study of Intratumoral Oncolytic Virus Injection… | Jie Yuan，MD new | |
| 2026-09-22 | NCT07834268 Feasibility of Multi-cancer Early Detection Test in Screening Population (NQMD-CS) | Fifth Affiliated Hospital of Guangzhou Medical University new | |
| 2026-09-17 | NCT07825519 Effectiveness of Enhanced Web-Based Health Education on Self-Care Practices and Quality… | University Medical Center Ho Chi Minh City (UMC) new | |
| 2026-09-15 | NCT07820644 A Cohort Study (Risk Prediction of HCC in Patients With Chronic Liver Disease) | Cai Qingxian new | |
| 2026-09-14 | NCT07817147 CREO - Microwave Ablation Feasibility Study | Banner Health new | |
| 2026-09-08 | NCT07808164 ENPP1/cGAS (EG) and FAP Expression Profiles in Solid Tumors: An Immunohistochemical Study… | Tam Anh Research Institute new | |
| 2026-08-27 | NCT07790419 A Prospective, Single-Arm, Open-Label Clinical Study of the Efficacy and Safety of… | Zhai Wenlong new | Phase 4 |
| Early Phase 1 | 22 | |
| Phase 1 | 141 | |
| Phase 1/2 | 94 | |
| Phase 2 | 307 | |
| Phase 2/3 | 25 | |
| Phase 3 | 72 | |
| Phase 4 | 28 |
Sun Yat-sen University (45) · Tongji Hospital (29) · Tianjin Medical University Cancer Institute and Hospital (25) · Second Affiliated Hospital of Guangzhou Medical University (23) · Shanghai Zhongshan Hospital (22) · West China Hospital (21) · M.D. Anderson Cancer Center (19) · Assistance Publique - Hôpitaux de Paris (18) · AstraZeneca (17) · Fudan University (17)