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M.D. Anderson Cancer Center clinical trial pipeline

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1,062 active trials 508 recruiting 37 Phase 3 55 disease areas 106 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days showing 41 of 106 changes on 19 trials

2026-09-24
Trial terminated
Trial terminated: \<\&%% participation
Primary completion confirmed: September 2026 (last estimated March 2028)
NCT06015295 A Pilot Study to Assess the Clinical Utility of 18F-Fluciclovine (Axumin) PET-CT for…
2026-09-12
Withdrawn before enrolling
Trial withdrawn: 0 participants
Primary completion moved earlier: 2029-01-01 → 2026-09-04
Completion moved earlier: 2031-01-01 → 2026-09-04
NCT07720115 Phase 2 Trial Of S-531011 With RadScopal In Previously Treated Metastatic Colorectal… · Phase 2
2026-09-16
Trial terminated
Trial terminated: PI Request
Primary completion confirmed: August 2026 (last estimated December 2026)
NCT03634267 MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA… · Phase 1
2026-09-16
Trial status changed: Active, Not Recruiting → Withdrawn
Trial withdrawn: No Participants Enrolled
NCT04286386 Development and Evaluation of a Quantitative HP MRI for Clinical Prostate Cancer Exam
2026-09-30
Primary completion pushed: 2026-08-19 → 2028-08-19
Completion pushed: 2026-08-19 → 2028-08-19
NCT00496522 Proton Beam Therapy for Chondrosarcoma · Phase 2
2026-09-30
Primary completion pushed: 2026-08-30 → 2030-03-01
Completion pushed: 2026-08-30 → 2030-03-01
NCT02893397 Supervised Exercise in Improving Physical Fitness Before Surgery in Patients With…
2026-09-30
Primary completion pushed: 2026-03-01 → 2027-06-30
Completion pushed: 2026-06-30 → 2027-06-30
NCT04890834 Dyadic Yoga Intervention for the Improvement of Healthcare Utilization and Quality of…
2026-09-29
Primary completion pushed: 2026-04-01 → 2028-10-11
Enrollment closed, study ongoing
Final enrollment: 86 participants (planned 66)
Completion pushed: 2028-04-01 → 2028-10-31
NCT07140770 Sleep and Physical Activity in Patient and Caregiver Dyads Following Allogeneic…
2026-09-25
Primary completion pushed: 2026-09-30 → 2028-09-30
Completion pushed: 2027-09-30 → 2028-09-30
NCT07407920 Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR… · Phase 2
2026-09-25
Primary completion pushed: 2026-05-31 → 2028-05-31
Completion pushed: 2026-05-31 → 2028-05-31
NCT03128866 Tranexamic Acid in Reducing Blood Loss in Patients With Pelvic Tumors Undergoing… · Early Phase 1
2026-09-26
Primary completion pushed: 2026-08-01 → 2028-08-01
NCT06667427 Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer…
2026-09-26
Primary completion pushed: 2026-12-31 → 2028-12-31
NCT07105046 Facilitators and Barriers to Cancer Treatment Among Texas Residents
2026-09-26
Primary completion pushed: 2026-09-01 → 2028-09-01
Completion pushed: 2026-09-01 → 2028-09-01
NCT04216732 Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management
2026-09-26
Primary completion pushed: 2026-03-31 → 2028-03-31
NCT07142005 Cultural Adaptation of an Educational Tool in Medullary Thyroid Cancer
2026-09-25
Primary completion pushed: 2026-04-30 → 2028-04-30
Completion pushed: 2026-04-30 → 2028-04-30
NCT03085043 Magnetic Resonance Whole Body Diffusion-Weighted Imaging in Finding Bone or Lymph Node…
2026-09-23
Primary completion pushed: 2026-04-30 → 2028-04-30
Completion pushed: 2026-04-30 → 2028-04-30
NCT05035706 Anti-Leukemia Immune Responses After Irradiation of Extramedullary Tumors · Early Phase 1
2026-09-15
Primary completion pushed: 2027-09-30 → 2030-09-30
Completion pushed: 2027-09-30 → 2030-09-30
NCT00525720 Brachytherapy for Prostatic Carcinoma Patients · Phase 2
2026-09-15
Primary completion pushed: 2026-09-30 → 2028-09-30
Completion pushed: 2026-09-30 → 2028-09-30
NCT01709292 Vemurafenib Neoadjuvant Trial in Locally Advanced Thyroid Cancer · Phase 2
2026-09-12
Primary completion pushed: 2026-09-30 → 2027-09-30
NCT00525720 Brachytherapy for Prostatic Carcinoma Patients · Phase 2
2026-09-12
Primary completion pushed: 2026-12-01 → 2028-12-01
NCT06229912 A Phase II Study of the Menin Inhibitor Revumenib in Leukemia Associated With… · Phase 2

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-10-01 NCT07850973 Phase 1/2 Study Of PARP Inhibition With Olaparib To Enhance The Efficacy Of High-Dose… Phase 1/2 Not Yet Recruiting
2026-10-01 NCT07852858 Supporting Families In Coping With Parental Cancer: A Multi-Site Randomized Controlled… Not Yet Recruiting
2026-10-01 NCT07852949 Understanding the Role of MyCareGorithm as a Visual Digital Platforms in Cancer Treatment… Not Yet Recruiting
2026-09-28 NCT07843537 MINTER Trial: Metal Intervention aNd ThErapy With Radiotherapy In Thoracic Cancer Using… Phase 2 Not Yet Recruiting
2026-09-28 NCT07843550 A Phase 1/2 Trial Of Larotrectinib And Pembrolizumab In Patients With Solid Tumors… Phase 1/2 Not Yet Recruiting
2026-09-21 NCT07829445 PRECISE LBCL: Precision Treatment Readiness Through Comprehensive Genomic Sequencing in… Not Yet Recruiting
2026-09-21 NCT07829471 Impact of Routine Electronic Patient-Reported Outcome (ePRO)Symptom Monitoring During… Not Yet Recruiting
2026-09-21 NCT07832266 Proactively Intervening On Early Cranial Nerve Injury As A Delayed Sequela Of… Phase 1 Not Yet Recruiting
2026-09-15 NCT07819474 Optimizing Tumor-Infiltrating Lymphocyte (TIL) Harvest Site and Patient Selection With… Not Yet Recruiting
2026-09-15 NCT07819513 Spatial Computing With the Apple Vision Pro in Image-guided Procedures Recruiting

Active trials by phase

Early Phase 1
27
Phase 1
135
Phase 1/2
93
Phase 2
349
Phase 2/3
12
Phase 3
25
Phase 4
8
Not charted: 413 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 1,062

NCT IDTitleConditionStatusUpdated
Phase 4
NCT07169825 Evaluation of Targeted Radionuclide Therapy of Lu-177 PSMA in Patients With Compromised… Lu-177 PSMA Recruiting 2026-08-04
NCT06162377 Methylnatrexone In Resectable Head and Neck Squamous Cell Carcinoma (MINK). A "Window of… Head and Neck Squamous Cell Carcinoma Recruiting 2026-06-10
NCT04265430 Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in… Malignant Oral Cavity Neoplasm Recruiting 2026-05-22
NCT04604509 Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking… Cigarette Smoking-Related Carcinoma Recruiting 2026-05-04
NCT06049134 Immunogenicity and Clinical Efficacy of 20-valent Pneumococcal Conjugate Vaccine (PCV20)… Lymphoma Active, Not Recruiting 2026-09-15
NCT02162849 Reward Sensitivity and Pharmacotherapy for Smoking Cessation Tobacco Use Cessation Active, Not Recruiting 2026-07-16
NCT03023631 Gardasil 9 Vaccine in Preventing HPV Infection in Patients With Hematologic Malignancies… Allogeneic Hematopoietic Stem Cell Transplant Recipient Active, Not Recruiting 2026-07-16
NCT04296305 Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone… Hematopoietic and Lymphoid Cell Neoplasm Active, Not Recruiting 2026-06-16
Phase 3
NCT04575935 Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage… Advanced Ovarian Carcinoma Recruiting 2026-09-14
NCT06593431 Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease… Pancreas Cancer Recruiting 2026-07-27
NCT06274047 PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and… Androgen Axis Suppression Recruiting 2026-07-22
NCT03583710 Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With… ENSAT Stage I Adrenal Cortex Carcinoma Recruiting 2026-07-16
NCT05053867 A Randomized Controlled Trial of Inhaled Tranexamic Acid for the Treatment of Pulmonary… Pulmonary Hemorrhage Recruiting 2026-07-16
NCT05774678 Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated… Breast Cancer Recruiting 2026-06-23
NCT06851507 A Pilot Clinical Trial Comparing Topical Fluorouracil to Fluorouracil Plus Calcipotriene… Multiple Actinic Keratoses Recruiting 2026-05-13
NCT06065449 A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs… Bone Metastases Recruiting 2026-01-14
NCT01696734 Domperidone in Treating Patients With Gastrointestinal Disorders Digestive System Disorder Active, Not Recruiting 2026-09-24
NCT03391869 Nivolumab and Ipilimumab With or Without Local Consolidation Therapy in Treating Patients… Lung Adenocarcinoma Active, Not Recruiting 2026-09-18
NCT01592968 Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With… Metastatic Malignant Neoplasm Active, Not Recruiting 2026-09-16
NCT06200181 Effect of Olanzapine on Opioid Craving and Misuse Among Patients Receiving Opioids for… Misuse, Opioid Active, Not Recruiting 2026-09-10
NCT01893307 Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating… Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7 Active, Not Recruiting 2026-08-21
NCT05836870 Tele-PancFit: A Multi-site Trial of Video-based Strengthening Exercise Prehabilitation… Pancreatic Cancer Active, Not Recruiting 2026-08-12
NCT00950001 Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain… Metastatic Malignant Neoplasm in the Brain Active, Not Recruiting 2026-08-11
NCT04188418 Fentanyl Buccal Tablet or Morphine for Exertional Dyspnea in Cancer Patients Hematopoietic and Lymphoid Cell Neoplasm Active, Not Recruiting 2026-08-11
NCT03741673 Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases Malignant Neoplasm Active, Not Recruiting 2026-08-10
See all 1,062 active M.D. Anderson Cancer Center trials with filters →

Disease areas by active trials, top 10 of 55

Leukemia (117) · Breast Cancer (93) · Lung Cancer (57) · Acute Myeloid Leukemia (AML) (56) · Head & Neck Cancer (51) · Colorectal Cancer (48) · Melanoma (43) · Prostate Cancer (43) · Myelodysplastic Syndromes (MDS) (39) · Ovarian Cancer (39)

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