Also listed under Neuroendocrine Tumors, Skin Neoplasms

Disease landscape

Melanoma clinical trials

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-20

What changed in the last 30 days

71 trials changed in the last 30 days: 4 stopped, 30 with notable changes, 37 with minor changes only.

  1. Notable

    Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation · 5-20 Brain Metastases: A Phase III, Randomized Trial

    Primary endpoint(s) modified

    Also in this update: Sponsor changed: Dana-Farber Cancer Institute to Brigham and Women's Hospital; Results posted: Sep 29, 2026

    Brigham and Women's HospitalNot applicable NCT03075072 Registry history of NCT03075072 on ClinicalTrials.gov (opens the registry)

Show 37 trials with minor changes only
  1. Minor
    5 trials marked Unknown by the registry's verification sweep

    Registry verification sweep

    Changed

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-10-13 NCT07870265 Detection of the BRAF V600E Mutation in Liquid Biopsy Using the CRISPR/Cas12a System Masaryk Memorial Cancer Institute new
2026-10-06 NCT07861022 Biomechanical Characterization of Skin Properties Using Impact Based-Analysis Method… Centre Hospitalier Universitaire Henri Mondor, Assistance Publique Hôpitaux de Paris new
2026-10-05 NCT07857616 SI-B036-ST-101 in Advanced/Metastatic Solid Tumors SystImmune Inc. new Phase 1
2026-09-25 NCT07841925 A Study of BL-M08D in Patients With Locally Advanced or Metastatic Melanoma and Other… Sichuan Baili Pharmaceutical Co., Ltd. new Phase 1/2
2026-09-21 NCT07831083 Skin Cancer Among Outdoor Workers Assuta Medical Center new
2026-09-08 NCT07808164 ENPP1/cGAS (EG) and FAP Expression Profiles in Solid Tumors: An Immunohistochemical Study… Tam Anh Research Institute new
2026-08-12 NCT07760012 68Ga-SorB PET/CT Imaging in Patients With Solid Tumors Peking University Third Hospital new
2026-08-05 NCT07747935 Study of Neoadjuvant RBP-01 In Patients With Primary Uveal Melanoma ReBio Pharma new Phase 1/2

Active trials by phase

Early Phase 1
16
Phase 1
152
Phase 1/2
125
Phase 2
200
Phase 2/3
11
Phase 3
52
Phase 4
9
Not charted: 274 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Top sponsors by active trials in this area

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Active trials