Sponsor Pipeline

National Cancer Institute (NCI) Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-07-07
758
Active Trials
291
Recruiting
97
Phase 3
10
Disease Areas
126
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-07-07 NCT07198074
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin…
Trial sites expanded: 223 -> 228 locations
2026-07-07 NCT06577441
Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment…
Trial sites expanded: 140 -> 143 locations
2026-07-07 NCT07061977
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation…
Trial sites expanded: 290 -> 294 locations
2026-07-03 NCT03412877
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors…
date change Primary completion pushed: 2027-03-23 -> 2028-03-23
2026-07-03 NCT03412877
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors…
date change Completion pushed: 2028-03-23 -> 2029-03-23
2026-07-03 NCT00867464
Extended Follow Up of Young Women in Costa Rica Who Received Vaccine for Human…
date change Primary completion pushed: 2026-04-30 -> 2026-12-23
2026-07-03 NCT00867464
Extended Follow Up of Young Women in Costa Rica Who Received Vaccine for Human…
date change Completion pushed: 2026-04-30 -> 2026-12-23
2026-07-03 NCT07391774
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed…
Trial sites expanded: 28 -> 36 locations
2026-07-02 NCT05836584
Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional…
Enrollment reduced: 240 -> 2 participants
2026-07-02 NCT05836584
Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional…
date change Primary completion moved earlier: 2027-10-31 -> 2026-01-20
2026-07-02 NCT05836584
Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional…
date change Completion moved earlier: 2027-10-31 -> 2027-06-28
2026-07-02 NCT05211323
A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy…
date change Primary completion pushed: 2026-06-30 -> 2026-09-30
2026-07-02 NCT05211323
A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy…
date change Completion pushed: 2026-06-30 -> 2026-09-30
2026-07-02 NCT07391774
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed…
Trial sites expanded: 25 -> 28 locations
2026-07-01 NCT05237947
Single-Dose HPV Vaccination for the Prevention of Cervical Cancer in Young Adult Women in…
date change Primary completion pushed: 2026-05-31 -> 2026-08-31
2026-07-01 NCT05237947
Single-Dose HPV Vaccination for the Prevention of Cervical Cancer in Young Adult Women in…
date change Completion pushed: 2026-05-31 -> 2026-12-31
2026-07-01 NCT06103838
18F-Fluciclovine PET/CT in Multiple Myeloma
date change Primary completion pushed: 2026-12-06 -> 2027-12-06
2026-07-01 NCT06103838
18F-Fluciclovine PET/CT in Multiple Myeloma
date change Completion pushed: 2031-12-06 -> 2032-12-06
2026-07-01 NCT04287868
Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies
Trial completed
2026-07-01 NCT04287868
Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies
date change Completion moved earlier: 2026-07-01 -> 2026-05-14
Showing 20 of 126 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-29 NCT07672483 IL-12 Genetically Engineered Myeloid Cells in Participants With Relapsed, Refractory… Phase 1 Not Yet Recruiting
2026-06-25 NCT07667400 Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma… Phase 1/2 Not Yet Recruiting
2026-06-16 NCT07649304 AMC 120, Glofitamab Plus Chemoimmunotherapy in Newly Diagnosed HIV-Associated Large… Phase 1 Not Yet Recruiting
Active Trials by Phase
Phase 4
1
Phase 3
79
Phase 2/3
18
Phase 2
301
Phase 1/2
79
Phase 1
155
Early Phase 1
1
Not specified
124
Active Trials — top 25 of 758
NCT IDTitleConditionStatus
Phase 4
NCT05237947 Single-Dose HPV Vaccination for the Prevention of Cervical Cancer in Young Adult Women in… Human Papillomavirus-Related Cervical Carcinoma Active, Not Recruiting
Phase 3
NCT06589804 Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment… Metastatic Head and Neck Squamous Cell Carcinoma Recruiting
NCT04166409 A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With… Low Grade Astrocytoma Recruiting
NCT06524544 A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus… Locally Advanced Urothelial Carcinoma Recruiting
NCT06337318 Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden… Classic Follicular Lymphoma Recruiting
NCT06422806 Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for… Metastatic Dedifferentiated Liposarcoma Recruiting
NCT04269902 Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or… Chronic Lymphocytic Leukemia Recruiting
NCT05675410 A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs… Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 Recruiting
NCT06058377 Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment… Anatomic Stage II Breast Cancer AJCC v8 Recruiting
NCT06096844 Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With… Advanced Lung Non-Small Cell Carcinoma Recruiting
NCT06172296 Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of… Ganglioneuroblastoma, Nodular Recruiting
NCT06498635 Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard… Lung Non-Small Cell Carcinoma Recruiting
NCT07391774 Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed… Anatomic Stage II Breast Cancer AJCC v8 Recruiting
NCT04181060 Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With… Advanced Lung Non-Squamous Non-Small Cell Carcinoma Recruiting
NCT04267848 Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy… Lung Non-Small Cell Carcinoma Recruiting
NCT07061977 Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation… Locally Advanced Cervical Adenocarcinoma Recruiting
NCT07198074 Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin… Advanced Endometrial Carcinoma Recruiting
NCT07388524 Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early… Lung Non-Small Cell Carcinoma Recruiting
NCT00565851 Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After… Clear Cell Adenocarcinoma Active, Not Recruiting
NCT01169337 Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering… Light Chain Deposition Disease Active, Not Recruiting
NCT01886872 Rituximab and Bendamustine Hydrochloride, Rituximab and Ibrutinib, or Ibrutinib Alone in… Stage I Chronic Lymphocytic Leukemia Active, Not Recruiting
NCT00098475 Lenalidomide and Dexamethasone With or Without Thalidomide in Treating Patients With… DS Stage I Multiple Myeloma Active, Not Recruiting
NCT04530565 Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or… B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 Active, Not Recruiting
NCT02003222 Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly… Acute Lymphoblastic Leukemia Active, Not Recruiting
NCT00217737 Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating… Colon Adenocarcinoma Active, Not Recruiting
View all 758 active National Cancer Institute (NCI) trials with filters →
Disease Areas
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