Also listed under Breast Diseases

ClinicalTrials.gov term: Breast Neoplasms

Disease landscape

Breast Cancer clinical trials

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-20

What changed in the last 30 days

322 trials changed in the last 30 days: 8 stopped, 153 with notable changes, 161 with minor changes only.

  1. Stopped

    SAFIR 03 · Detection of Tumor DNA in the Blood of Patients Receiving Standard Therapy for Hormone Receptor-positive (HR+) Non-HER2 Expressing (HER2-) Metastatic Breast Cancer as a Tool to Select Those Who May Benefit From the Next Course of Fulvestrant in Combination With Alpelisib or Ribociclib

    Trial terminated

    Also in this update: Final enrollment: 4 participants — 2% of the 162 planned; Primary completion date changed from estimate of Jul 2028 to Mar 30, 2025

    UNICANCERPhase 2 NCT05625087 Registry history of NCT05625087 on ClinicalTrials.gov (opens the registry)

  2. Stopped

    SERCABOT · Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome

    Trial status changed: Recruiting → Withdrawn

    Also in this update: Start date changed from estimate of Oct 31, 2026 to Jun 10, 2025; Primary completion date changed from estimate of Aug 30, 2027 to Sep 22, 2026

    Centre Oscar LambretPhase 2 NCT06807164 Registry history of NCT06807164 on ClinicalTrials.gov (opens the registry)

  3. Stopped

    ALTERNATIVE · Telemonitoring Platform "CUREETY TECHCARE" vs Standard of Care for mTBNC Patients Initiating a First-line Treatment

    Trial terminated

    Also in this update: Final enrollment: 31 participants — 7% of the 472 planned; Primary completion date changed from estimate of Sep 1, 2026 to Dec 1, 2025

    UNICANCERNot applicable NCT06505018 Registry history of NCT06505018 on ClinicalTrials.gov (opens the registry)

Show 161 trials with minor changes only
  1. Minor

    DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03]

    Trial completed

    Also in this update: Study completion date changed from estimate of Jul 30, 2026 to Aug 31, 2026

    Daiichi SankyoPhase 3 NCT03529110 Registry history of NCT03529110 on ClinicalTrials.gov (opens the registry)

  2. Minor

    Ribociclib Administered Concurrently With Postoperative Radiation Therapy · High-Risk, HR+/HER2- Breast Cancer

    Enrollment closed, study ongoing

    Also in this update: Primary completion pushed from Oct 2026 to Feb 2027; Study completion moved earlier from Oct 2030 to Feb 2030

    University of Michigan Rogel Cancer CenterPhase 1 NCT05996107 Registry history of NCT05996107 on ClinicalTrials.gov (opens the registry)

  3. Minor

    Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally Advanced Premenopausal Hormone Receptor Positive Breast Cancer Patients

    Primary completion pushed from Sep 26, 2028 to Dec 21, 2028

    Also in this update: Study completion moved earlier from Sep 26, 2029 to Jun 21, 2029

    Mayo ClinicPhase 2 NCT07460752 Registry history of NCT07460752 on ClinicalTrials.gov (opens the registry)

  4. Minor

    SYNERGY · Paclitaxel + Carboplatin + Durvalumab With or Without Oleclumab for Previously Untreated Locally Recurrent Inoperable or Metastatic TNBC

    Study completion pushed from Dec 2025 to Dec 2028

    Also in this update: Primary completion date changed from estimate of Mar 2025 to May 21, 2021

    Jules Bordet InstitutePhase 1/2 NCT03616886 Registry history of NCT03616886 on ClinicalTrials.gov (opens the registry)

  5. Minor
    38 trials marked Unknown by the registry's verification sweep
    1. Minor

      PEMCLOCK · Association of Pembrolizumab Infusion Time and Efficacy · Non-metastatic Triple-negative Breast Cancer (TNBC) Treated With Neoadjuvant Chemotherapy and Immunotherapy

      Registry marked status Unknown (sponsor has not verified the record since Apr 2024); last known: Not Yet Recruiting

      Assistance Publique - Hôpitaux de ParisNot specified NCT06418139 Registry history of NCT06418139 on ClinicalTrials.gov (opens the registry)

      Changed

    2. Minor

      NASBP-B-09 · Anastrozole Adjuvant Trial - Study of Anastrozole Compared to NOLVADEX (Tamoxifen Citrate) for Adjuvant Treatment of Early Breast Cancer Clinical Studies), Adjunct Cytotoxic Chemotherapy and Malignant Joint Tumor

      Registry marked status Unknown (sponsor has not verified the record since Nov 2023); last known: Not Yet Recruiting

      DR. DIANE CHISESI NFS. MD. PHD.Not specified NCT06154590 Registry history of NCT06154590 on ClinicalTrials.gov (opens the registry)

      Changed

    Registry verification sweep

    Changed

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-10-19 NCT07879963 Safety and Effectiveness Study of Single-Port Surgical System in Breast Tumor Surgery haiyanli new
2026-10-19 NCT07881679 Breast MRI for Early Detection of Breast Cancer in Thuringia Jena University Hospital new
2026-10-16 NCT07878598 Efficacy of Complete Decongestive Therapy for Limb Lymphedema: Response Profile and… Ryazan State Medical University new
2026-10-16 NCT07877740 Feasibility of a Standardized Fascial Plane Block Protocol for Breast Cancer Surgery Hôpital Fribourgeois new
2026-10-16 NCT07877376 Impact of Cognitive Impairment on Chronic Pain in Breast Cancer Nadine ATTAL new
2026-10-15 NCT07874880 MTX-531-001 Phase 1 Study in Advanced Solid Tumors MEKanistic Therapeutics, Inc. new Phase 1
2026-10-08 NCT07864909 Physical Activity Education and Quality of Life Study in Breast Cancer Chemotherapy… International Hellenic University new
2026-10-08 NCT07865884 Tissue Validation of Mammographic Breast Arterial Calcification in Mastectomy Specimens Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital new
2026-10-08 NCT07865507 Divergent Long-Term Clinical Courses in Two Men With Breast Cancer Azerbaijan Medical University new
2026-10-06 NCT07861932 A Phase 1/2a Study of K-1728 in Advanced Solid Tumors KymaThera, Inc. new Phase 1/2

Active trials by phase

Early Phase 1
43
Phase 1
339
Phase 1/2
268
Phase 2
942
Phase 2/3
34
Phase 3
400
Phase 4
68
Not charted: 2,322 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Top sponsors by active trials in this area

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