RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

[...] C) with confirmed HER2-positive status by central laboratory. Measurable disease only as per by RECIST v1.1/RANO-BM in stage 1. Non-measurable disease allowed in stage 2. Prev [...] ously untreated CNS metastases, or leptomeningeal metastases. At least one prior line of anti-HER2-based therapy for LAI or metastatic disease. Prior anti-HER2 antibody-drug conjugate (ADC), such as tras [...] b emtansine (T-DM1), in any treatment setting. Participants for whomwithout prior ADC therapy wasmay only be enrolled if approved standard-of-care (SOC) anti-HER2 ADC is not appropriatelocally (e.g.accessible at screening, [...]