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City of Hope Medical Center clinical trial pipeline

Get alerts when City of Hope Medical Center's trials change

331 active trials 156 recruiting 5 Phase 3 45 disease areas 50 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days showing 37 of 50 changes on 19 trials

2026-10-02
Withdrawn before enrolling
Trial withdrawn: Study Abandoned withdrawn
NCT07218692 RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on… · Phase 2
2026-09-23
Recruitment suspended
Recruitment suspended: Safety Issues
NCT05861050 Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients… · Phase 1/2
2026-09-11
Recruitment suspended
Recruitment suspended: pending amendment
NCT06572605 External Beam Radiation Therapy in Combination With Talquetamab for the Treatment of… · Phase 1/2
2026-09-11
Recruitment suspended
Recruitment suspended: Budget Issue
NCT06014827 Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy… · Phase 2
2026-09-12
Recruitment suspended
Recruitment suspended: Safety Issues
NCT07025538 Biomarker-Guided Ruxolitinib for the Prevention of Chronic Graft Versus Host Disease… · Phase 1
2026-09-11
Recruitment suspended
Recruitment suspended: Budget Issue
NCT06549478 Biology-Guided Radiation Therapy for the Treatment of Patients With Bone Metastases · Phase 1
2026-09-04
Recruitment suspended
Recruitment suspended: Accrual Goal Met
NCT06500377 Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer…
2026-10-02
Primary completion pushed: 2026-09-08 → 2027-07-27
Completion pushed: 2026-09-08 → 2027-07-27
NCT05718869 Tafasitamab and Zanubrutinib for the Treatment of Patients With Newly Diagnosed Chronic… · Phase 2
2026-10-02
Primary completion pushed: 2026-08-21 → 2027-05-21
Completion pushed: 2026-08-21 → 2027-05-21
NCT04305834 Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer. · Phase 2
2026-10-02
Primary completion pushed: 2026-09-10 → 2027-08-24
Completion pushed: 2026-09-10 → 2027-08-24
NCT05672173 Lisocabtagene Maraleucel, Nivolumab and Ibrutinib for the Treatment of Richter's… · Phase 2
2026-10-02
Primary completion pushed: 2026-09-02 → 2027-02-23
Enrollment closed, study ongoing
Completion pushed: 2026-09-02 → 2027-02-23
NCT04484012 Modified Immune Cells (CD19 CAR T Cells) and Acalabrutinib for the Treatment of Relapsed… · Phase 2
2026-10-02
Primary completion pushed: 2026-09-14 → 2028-02-21
Completion pushed: 2026-09-14 → 2028-02-21
NCT07395050 Autologous CD6-CAR Treg Cells for Patients With Stage 3 Type 1 Diabetes · Early Phase 1
2026-10-02
Primary completion pushed: 2026-09-08 → 2027-08-09
Completion pushed: 2026-09-08 → 2027-08-09
NCT02337985 Gene Therapy and Combination Chemotherapy in Treating Patients With AIDS-Related… · Phase 1
2026-09-29
Primary completion pushed: 2026-09-08 → 2027-08-04
Completion pushed: 2026-09-08 → 2027-08-04
NCT03865992 Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase…
2026-09-23
Primary completion pushed: 2026-10-02 → 2027-10-02
Completion pushed: 2026-10-02 → 2027-10-02
NCT04561206 Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory… · Phase 2
2026-09-03
Primary completion pushed: 2026-08-03 → 2027-07-06
Completion pushed: 2026-08-03 → 2027-07-06
NCT03664830 Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell… · Phase 1
2026-09-30
Recruitment opened
NCT07583810 Non-covalent BTK Inhibitor Nemtabrutinib in Combination With the CD20 Monoclonal Antibody… · Phase 2
2026-09-26
Recruitment opened
NCT07271355 Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of… · Phase 3
2026-09-23
Recruitment resumed after suspension
NCT07025538 Biomarker-Guided Ruxolitinib for the Prevention of Chronic Graft Versus Host Disease… · Phase 1
2026-09-10
Trial status changed: Suspended → Completed
NCT05672355 A Vaccine Booster (GEO-CM04S1) for the Prevention of COVID-19 in Patients With Chronic… · Phase 2

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-25 NCT07842965 CCR5 Targeting Leronlimab in Combination With Hepatic Arterial Infusion Floxuridine and… Phase 1 Not Yet Recruiting
2026-09-15 NCT07819981 Prehabilitation for Improving Outcomes in Breast Cancer Patients Undergoing Neoadjuvant… Not Yet Recruiting
2026-09-10 NCT07812246 Zanubrutinib and Sonrotoclax for the Treatment of Relapsed Chronic Lymphocytic Leukemia… Phase 2 Not Yet Recruiting

Active trials by phase

Early Phase 1
11
Phase 1
108
Phase 1/2
14
Phase 2
85
Phase 3
5
Phase 4
1
Not charted: 107 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 331

NCT IDTitleConditionStatusUpdated
Phase 4
NCT05376878 An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+… Anatomic Stage IV Breast Cancer AJCC v8 Recruiting 2026-07-01
Phase 3
NCT07271355 Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of… Metastatic Appendix Carcinoma Recruiting 2026-09-25
NCT07186192 Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen… Hematologic Malignancies Recruiting 2026-08-28
NCT06763328 Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer… Anatomic Stage I Breast Cancer AJCC v8 Recruiting 2026-06-12
NCT06169267 Passive Music Intervention for the Reduction of Anxiety in Patients Undergoing Bone… Hematopoietic and Lymphoid System Neoplasm Active, Not Recruiting 2026-08-19
NCT04428905 Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal… Lung Non-Small Cell Carcinoma Active, Not Recruiting 2026-02-24
Phase 2
NCT04305834 Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer. Anatomic Stage IV Breast Cancer AJCC v8 Recruiting 2026-10-01
NCT07583810 Non-covalent BTK Inhibitor Nemtabrutinib in Combination With the CD20 Monoclonal Antibody… Conjunctival Mucosa-Associated Lymphoid Tissue Lymphoma Recruiting 2026-09-29
NCT06052826 Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T… B-Cell Non-Hodgkin Lymphoma Recruiting 2026-09-25
NCT04561206 Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory… Relapsed Classic Hodgkin Lymphoma Recruiting 2026-09-22
NCT06453044 Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or… Recurrent Grade 1 Follicular Lymphoma Recruiting 2026-09-22
NCT04930653 Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic… Folliculotropic Mycosis Fungoides Recruiting 2026-09-02
NCT05830058 Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the… Lung Non-Small Cell Carcinoma Recruiting 2026-08-31
NCT07365306 Epcoritamab, Rituximab, Gemcitabine and Oxaliplatin (R-GemOx) as Salvage Therapy Before… Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Recruiting 2026-08-28
NCT07275216 Pembrolizumab in Combination With Chemotherapy for the Treatment of Frail Hodgkin… Classic Hodgkin Lymphoma Recruiting 2026-08-20
NCT07582172 Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as… Acute Myeloid Leukemia With Complex Karyotype Recruiting 2026-08-20
NCT07202247 Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy… Prostate Carcinoma Recruiting 2026-08-17
NCT07226544 Ivonescimab Prior to Surgery for the Treatment of High-Risk Localized Clear Cell Renal… Localized Clear Cell Renal Cell Carcinoma Recruiting 2026-08-05
NCT07293403 Duvelisib Maintenance for the Treatment of Peripheral T-Cell Lymphomas Follicular Helper T-Cell Lymphoma Recruiting 2026-08-05
NCT05751434 A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer Prostate Cancer Recruiting 2026-07-30
NCT05672251 Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory… Recurrent Diffuse Large B-Cell Lymphoma Recruiting 2026-07-10
NCT07595874 Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable… Advanced Colon Adenocarcinoma Recruiting 2026-07-01
NCT06780787 FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before… Rectal Adenocarcinoma Recruiting 2026-06-29
NCT06815003 Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the… Acute Lymphoblastic Leukemia Recruiting 2026-06-29
NCT07650656 Fluorescence-Guided Surgical Resection for Reducing Unexpected Positive Margins in… High Grade Sarcoma Recruiting 2026-06-22
See all 331 active City of Hope Medical Center trials with filters →

Disease areas by active trials, top 10 of 45

Leukemia (59) · Breast Cancer (42) · Non-Hodgkin Lymphoma (33) · Acute Myeloid Leukemia (AML) (32) · Acute Lymphoblastic Leukemia (ALL) (31) · Colorectal Cancer (31) · Prostate Cancer (23) · Myelodysplastic Syndromes (MDS) (22) · Chronic Lymphocytic Leukemia (CLL) (20) · Lung Cancer (17)

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