ClinicalTrials.gov term: Precursor Cell Lymphoblastic Leukemia-Lymphoma

Disease landscape

Acute Lymphoblastic Leukemia (ALL) clinical trials

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-20

What changed in the last 30 days

51 trials changed in the last 30 days: 5 stopped, 18 with notable changes, 28 with minor changes only.

  1. Stopped

    OVERALL · Obinutuzumab Versus Rituximab for Acute Lymphoblastic Leukemia/PALG ALL7 "OVERALL

    Trial terminated

    Also in this update: Primary completion date changed from estimate of Dec 31, 2025 to Apr 21, 2026; Final enrollment: 49 participants (planned 124)

    Maria Sklodowska-Curie National Research Institute of OncologyPhase 2 NCT04920968 Registry history of NCT04920968 on ClinicalTrials.gov (opens the registry)

  2. Stopped

    Levofloxacin Prophylaxis to Prevent First Febrile Neutropenia in Pediatric ALL During Induction Phase

    Trial status changed: Not Yet Recruiting → Terminated

    Also in this update: Primary completion date changed from estimate of Jul 31, 2026 to Aug 31, 2026; Final enrollment: 49 participants (planned 124)

    Gadjah Mada UniversityPhase 4 NCT07320534 Registry history of NCT07320534 on ClinicalTrials.gov (opens the registry)

  3. Notable

    Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Bone Marrow or Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

    Primary completion pushed from Sep 2026 to Sep 2027

    Also in this update: Study completion pushed from Mar 2027 to Mar 2028

    Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsEarly Phase 1 NCT06398457 Registry history of NCT06398457 on ClinicalTrials.gov (opens the registry)

  4. Notable

    MSTH-CAR002 · This is a Phase I/II Interventional, Open-label Treatment Study Designed to Evaluate the Safety and Efficacy of Anti CD 19/22 CAR- T Cells Immunotherapy · Relapsed or Refractory Acute Lymphoblastic Leukemia/Lymphoma

    Enrolling by invitation only

    Also in this update: Study completion pushed from Dec 2031 to Dec 2032

    Minsk Scientific-Practical Center for Surgery, Transplantation and HematologyPhase 1/2 NCT07162571 Registry history of NCT07162571 on ClinicalTrials.gov (opens the registry)

Show 28 trials with minor changes only
  1. Minor
    4 trials marked Unknown by the registry's verification sweep
    1. Minor

      Blinatumomab as Maintenance Therapy · High-risk B-lineage Acute Lymphoblastic Leukemia Post Allogeneic Hematopoietic Cell Transplantation

      Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting

      Institute of Hematology & Blood Diseases Hospital, ChinaNot applicable NCT06658938 Registry history of NCT06658938 on ClinicalTrials.gov (opens the registry)

      Changed

    Registry verification sweep

    Changed

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-10-09 NCT07867509 A Clinical Trial on the Effect of Infant Formula Consumption on Growth, Immune… FrieslandCampina new Phase 3
2026-10-07 NCT07862010 Study of GI001 in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma and B-Cell Acute… Hematology department of the 920th hospital new Early Phase 1
2026-10-06 NCT07861477 Murottal as Adjunctive Intervention in Pediatric Universitas Airlangga new
2026-10-05 NCT07858214 Measurement of Ocular Microtremor With the iTremor Device in a Diverse US Cohort Head Diagnostics new
2026-09-10 NCT07814170 A Manualised Post-Traumatic Growth Intervention For People With Hematological Cancers In… University of West Attica new
2026-09-04 NCT07805096 Efficacy of a Smart Holistic Health Care Platform Intervention on Cancer Children and… National Defense Medical University, Taiwan new
2026-08-31 NCT07795099 A Single-center, Prospective, Exploratory Clinical Study LanZhou University new
2026-08-21 NCT07780123 Nurture by Nature Feasibility Study Ina Olmer Specht new
2026-08-18 NCT07770698 A Study of Sonrotoclax (BGB-11417) in Children With Relapsed or Refractory Acute Myeloid… BeOne Medicines new Phase 1/2
2026-08-13 NCT07763054 Low-dose Liposomal Amphotericin B for Antifungal Prophylaxis in Prolonged Neutropenia… Haikou Affiliated Hospital of Central South University Xiangya School of Medicine new

Active trials by phase

Early Phase 1
37
Phase 1
154
Phase 1/2
106
Phase 2
178
Phase 2/3
17
Phase 3
41
Phase 4
8
Not charted: 243 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Top sponsors by active trials in this area

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Active trials