Sponsor pipeline

St. Jude Children's Research Hospital clinical trial pipeline

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153 active trials 90 recruiting 23 disease areas 16 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days

2026-09-23
Primary completion pushed: 2026-08 → 2028-10
NCT02792582 A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected… · Phase 2
2026-09-18
Primary completion pushed: 2027-03 → 2027-07
NCT06819475 Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia…
2026-09-24
Primary endpoint(s) modified
Enrollment increased: 45 → 100 participants
NCT07790913 Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma · Phase 2
2026-09-04
Enrollment reduced: 228 → 116 participants
NCT07160621 Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric…
2026-09-25
Recruitment opened
Trial started: 2026-09-21 (last estimated 2026-10)
NCT07594392 Clinical Assessment and Targeted Imaging to Characterize High-Risk Atherosclerotic…
2026-09-18
Recruitment resumed after suspension
NCT05955261 A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients… · Phase 2
2026-09-15
Trial completed
Study completion confirmed: August 2026 (last estimated December 2027)
NCT04084067 Indocyanine Green (ICG) Guided Tumor Resection · Phase 1
2026-09-16
Enrollment closed, study ongoing
Final enrollment: 48 participants (planned 74)
NCT04065776 Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma
2026-09-09
Recruitment opened
NCT07805278 A Registry of Cases of Spinal Muscular Atrophy
2026-09-09
Enrollment increased: 15 → 20 participants
NCT06442761 SCD Stem Cell Mobilization and Apheresis Using Motixafortide · Phase 1
2026-10-01
Start date pushed: 2026-09 → 2026-10
NCT07805278 A Registry of Cases of Spinal Muscular Atrophy
2026-09-17
Trial started: 2026-09-14 (last estimated 2026-10-01)
NCT07531498 Muscle Aging Phenotypes in Childhood Cancer Survivors

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-22 NCT07834710 Using Bioimpedance Analysis to Monitor Fluid Status in Children Not Yet Recruiting
2026-09-21 NCT07830134 Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real Time… Recruiting
2026-09-04 NCT07805278 A Registry of Cases of Spinal Muscular Atrophy Recruiting
2026-09-03 NCT07801976 Positron Emission Tomography (PET) Imaging of Reactive Oxygen and Nitrogen Species: Human… Early Phase 1 Not Yet Recruiting

Active trials by phase

Early Phase 1
4
Phase 1
17
Phase 1/2
10
Phase 2
38
Phase 2/3
2
Phase 4
1
Not charted: 81 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 153

NCT IDTitleConditionStatusUpdated
Phase 4
NCT06289673 Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute… Acute Lymphoblastic Leukemia Recruiting 2026-07-14
Phase 2/3
NCT03117751 Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and… Acute Lymphoblastic Leukemia Active, Not Recruiting 2026-06-17
NCT01046825 Mature B-Cell Lymphoma And Leukemia Study III Mature B-Cell Lymphoma Active, Not Recruiting 2026-06-02
Phase 2
NCT05955261 A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients… Acute Myeloid Leukemia Recruiting 2026-09-17
NCT04558736 Haploidentical HCT for Severe Aplastic Anemia Aplastic Anemia Recruiting 2026-09-16
NCT05535166 Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly… Medulloblastoma Recruiting 2026-09-15
NCT07428993 Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map… Pediatric Osteosarcoma Recruiting 2026-09-01
NCT06390319 Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed… T-cell Acute Lymphoblastic Leukemia Recruiting 2026-08-10
NCT07085338 A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy… Neuroblastoma Recurrent Recruiting 2026-08-07
NCT07616154 Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease Sickle Cell Disease Recruiting 2026-07-23
NCT06533748 Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia… Acute Lymphoblastic Leukemia Recruiting 2026-07-16
NCT06023641 Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and… Rhabdomyosarcoma Recruiting 2026-06-15
NCT07228741 Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL… Acute Lymphoblastic Leukemia Recruiting 2026-06-04
NCT06528691 Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With… High Grade Glioma Recruiting 2026-05-13
NCT05583721 Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle… Sickle Cell Disease Recruiting 2026-05-06
NCT04968990 Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation… Wilms Tumor Recruiting 2026-04-23
NCT06847269 CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive… Acute Lymphoblastic Leukemia Recruiting 2026-03-25
NCT05664126 Haplo-identical Viral-Specific T-cells for Treatment of Cytomegalovirus and Adenovirus… Cytomegalovirus Recruiting 2026-02-23
NCT04733534 An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult… Frailty Active, Not Recruiting 2026-09-30
NCT07790913 Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma Acute Lymphoblastic Leukemia in Remission Not Yet Recruiting 2026-09-23
NCT02792582 A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected… Craniopharyngioma Active, Not Recruiting 2026-09-22
NCT03849651 TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use… Acute Lymphoblastic Leukemia (ALL) Active, Not Recruiting 2026-09-15
NCT02114229 Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors Malignant Rhabdoid Tumor Active, Not Recruiting 2026-09-01
NCT04362293 Reduced Intensity Transplantation for Severe Sickle Cell Disease Sickle Cell Disease Active, Not Recruiting 2026-09-01
NCT01419067 A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or… Craniopharyngioma Active, Not Recruiting 2026-08-19
See all 153 active St. Jude Children's Research Hospital trials with filters →

Disease areas by active trials, top 10 of 23

Acute Lymphoblastic Leukemia (ALL) (26) · Leukemia (26) · Sickle Cell Disease (17) · Hodgkin Lymphoma (14) · Sarcoma (13) · Acute Myeloid Leukemia (AML) (10) · Myelodysplastic Syndromes (MDS) (7) · Non-Hodgkin Lymphoma (7) · Glioma (5) · Melanoma (4)

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