Sponsor Pipeline

St. Jude Children's Research Hospital Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
148
Active Trials
88
Recruiting
2
Phase 3
10
Disease Areas
11
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-12 NCT03573700
Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of…
date change Completion pushed: 2026-07-01 -> 2027-07-01
2026-07-24 NCT07616154
Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease
Recruitment opened
2026-07-24 NCT06053268
Mindfulness Interventions to Improve Health Activation, Coping, and Stress Among…
Primary endpoint(s) modified
2026-07-23 NCT03849651
TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use…
date change Completion pushed: 2026-06-07 -> 2027-12-31
2026-07-23 NCT02530658
Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients
date change Primary completion pushed: 2033-12-31 -> 2045-12-31
2026-07-23 NCT02530658
Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients
date change Completion pushed: 2038-12-31 -> 2053-12-31
2026-07-21 NCT03226158
Next Generation Pathogen Sequencing for Prediction of Adverse Events
date change Completion pushed: 2026-07-01 -> 2027-07-01
2026-07-21 NCT05664113
Feasibility, Safety, and Potential Efficacy of Fecal Microbiota Transplantation (FMT) for…
Primary endpoint(s) modified
2026-07-19 NCT07663539
Insights From Bereaved Parents and Oncologists
Recruitment opened
2026-07-19 NCT07663539
Insights From Bereaved Parents and Oncologists
date change Primary completion pushed: 2026-09 -> 2026-12
2026-07-19 NCT07663539
Insights From Bereaved Parents and Oncologists
date change Completion pushed: 2026-09 -> 2026-12
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-07-22 NCT07719972 Universal Newborn Screening For Sickle Cell Disease In Mozambique Not Yet Recruiting
Active Trials by Phase
Phase 4
1
Phase 2/3
2
Phase 2
36
Phase 1/2
10
Phase 1
18
Early Phase 1
3
Not specified
78
Active Trials — top 25 of 148
NCT IDTitleConditionStatus
Phase 4
NCT06289673 Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute… Acute Lymphoblastic Leukemia Recruiting
Phase 2/3
NCT01046825 Mature B-Cell Lymphoma And Leukemia Study III Mature B-Cell Lymphoma Active, Not Recruiting
NCT03117751 Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and… Acute Lymphoblastic Leukemia Active, Not Recruiting
Phase 2
NCT04558736 Haploidentical HCT for Severe Aplastic Anemia Aplastic Anemia Recruiting
NCT05535166 Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly… Medulloblastoma Recruiting
NCT05664126 Haplo-identical Viral-Specific T-cells for Treatment of Cytomegalovirus and Adenovirus… Cytomegalovirus Recruiting
NCT06847269 CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive… Acute Lymphoblastic Leukemia Recruiting
NCT04968990 Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation… Wilms Tumor Recruiting
NCT05583721 Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle… Sickle Cell Disease Recruiting
NCT06528691 Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With… High Grade Glioma Recruiting
NCT07428993 Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map… Pediatric Osteosarcoma Recruiting
NCT07228741 Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL… Acute Lymphoblastic Leukemia Recruiting
NCT06023641 Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and… Rhabdomyosarcoma Recruiting
NCT06533748 Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia… Acute Lymphoblastic Leukemia Recruiting
NCT07616154 Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease Sickle Cell Disease Recruiting
NCT07085338 A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy… Neuroblastoma Recurrent Recruiting
NCT06390319 Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed… T-cell Acute Lymphoblastic Leukemia Recruiting
NCT02790515 Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve… Acute Lymphoblastic Leukemia (ALL) Active, Not Recruiting
NCT01878617 A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma Medulloblastoma Active, Not Recruiting
NCT01946529 Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small… Desmoplastic Small Round Cell Tumor Active, Not Recruiting
NCT02125786 A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma Ependymoma Active, Not Recruiting
NCT00186992 Radiation Therapy to Treat Musculoskeletal Tumors Sarcoma, Ewing's Active, Not Recruiting
NCT02114229 Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors Malignant Rhabdoid Tumor Active, Not Recruiting
NCT03164057 A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia Acute Myeloid Leukemia Active, Not Recruiting
NCT04733534 An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult… Frailty Active, Not Recruiting
See all 148 active St. Jude Children's Research Hospital trials with filters →
Disease Areas
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