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H. Lee Moffitt Cancer Center and Research Institute clinical trial pipeline

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136 active trials 69 recruiting 2 Phase 3 32 disease areas 61 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days showing 40 of 61 changes on 19 trials

2026-09-29
critical
NCT04923542 SRS & Abemaciclib w/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain… · Phase 1/2
2026-09-26
critical
NCT06144606 Study of KTE-X19 in Minimal Residual Disease (MRD) Positive B-Cell Acute Lymphoblastic… · Phase 2
2026-09-26
critical
NCT05528133 Genomically Guided Radiation Therapy in the Management of Triple Negative Breast Cancer · Phase 2
2026-09-17
critical
NCT05757219 Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy · Phase 2
2026-09-16
critical
NCT05524935 Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma · Phase 2
2026-09-18
critical
NCT06047977 Tumor Infiltrating Lymphocyte Therapy for Pediatric High Risk Solid Tumors · Phase 1
2026-09-17
critical
NCT05681780 Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven… · Phase 1
2026-09-17
critical
NCT04741997 Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib Binimetinib… · Early Phase 1
2026-09-18
critical
NCT03924778 Modifying Diet to Improve Gut Microbiome
2026-09-18
notable
NCT04275557 Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous…
2026-09-17
critical
NCT06745895 Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening
2026-09-16
critical
NCT05692596 The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel…
2026-09-16
notable
NCT06423963 Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer
2026-09-26
critical
NCT05014282 Automated Video-Assisted Smoking Treatment for People Living With HIV
2026-09-24
notable
NCT04275557 Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous…
2026-09-17
notable
NCT03543189 Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation… · Phase 1/2

Active trials by phase

Early Phase 1
7
Phase 1
24
Phase 1/2
9
Phase 2
54
Phase 2/3
1
Phase 3
1
Not charted: 40 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 136

NCT IDTitleConditionStatusUpdated
Phase 3
NCT07357298 Phase III Trial of Brain MRI Surveillance in Stage IV Breast Cancer Breast Cancer Recruiting 2026-05-15
Phase 2/3
NCT03495427 PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher… Prostate Cancer Recruiting 2026-03-02
Phase 2
NCT06350318 Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas Follicular Lymphoma Recruiting 2026-09-28
NCT05528133 Genomically Guided Radiation Therapy in the Management of Triple Negative Breast Cancer Triple Negative Breast Cancer Recruiting 2026-09-25
NCT06144606 Study of KTE-X19 in Minimal Residual Disease (MRD) Positive B-Cell Acute Lymphoblastic… B-Cell Lymphoblastic Leukemia Recruiting 2026-09-25
NCT06553872 Phase 2 Open Label Randomized Study of Pirtobrutinib and Brexucabtagene Autoleucel in R/R… Mantle Cell Lymphoma Recruiting 2026-09-23
NCT06745882 Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/… Non-small Cell Lung Cancer Recruiting 2026-09-21
NCT05757219 Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy Diffuse Large B Cell Lymphoma Recruiting 2026-09-16
NCT05115474 Study of Screening Brain MRIs in Stage IV Breast Cancer Triple Negative Breast Cancer Recruiting 2026-09-15
NCT07686250 Evaluation and Outcomes of SAVI Scout MD for Localized Breast Surgery Breast Cancer Recruiting 2026-09-15
NCT06701812 Digoxin Medulloblastoma Study Medulloblastoma Recruiting 2026-08-26
NCT06660355 Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy Chronic Graft-versus-host Disease (cGVHD) Recruiting 2026-08-05
NCT07694986 Trial of Therapies With IT cDC1s Combined w/ IT Trastuzamab for Her+ or IT Nivolumab for… Breast Cancer Recruiting 2026-07-10
NCT06833502 Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer Breast Cancer Recruiting 2026-07-02
NCT07476001 Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC Metastatic Castration-resistant Prostate Cancer Recruiting 2026-05-15
NCT06760156 Tafasitamab and Lenalidomide as First Salvage Therapy for Residual Large B Cell Lym Large B-cell Lymphoma Recruiting 2026-04-03
NCT06137274 Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC Squamous Cell Carcinoma Recruiting 2026-04-01
NCT06295159 Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma Melanoma Stage III Recruiting 2026-04-01
NCT06553885 Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC Metastatic Colorectal Cancer Recruiting 2026-04-01
NCT06660368 BCL2i CLAG-M in R/R Acute Myeloid Leukemia Relapsed or Refractory Acute Myeloid Leukemia (AML) Recruiting 2026-04-01
NCT07007273 Pembrolizumab for Advanced Cutaneous Sarcomas Not Including Angiosarcoma Cutaneous Sarcoma Recruiting 2026-04-01
NCT06104592 Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk… Large B-cell Lymphoma Recruiting 2026-03-31
NCT07276386 Phase 2 Combination of Melphalan/HDS Via PHP + Tebentafusp in Treating Metastatic Uveal… Metastatic Uveal Melanoma Recruiting 2026-03-31
NCT05325632 Study of HER2 Directed Dendritic Cell (DC1) Vaccine + Weekly Paclitaxel, Trastuzumab &… HER2-positive Breast Cancer Recruiting 2026-03-02
NCT06511882 Discontinuation of Hypomethylating Agent and Venetoclax in Patients With AML MRD Acute Myeloid Leukemia Recruiting 2026-02-27

Disease areas by active trials, top 10 of 32

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