Sponsor Pipeline

H. Lee Moffitt Cancer Center and Research Institute Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
144
Active Trials
74
Recruiting
2
Phase 3
10
Disease Areas
8
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-07-31 NCT05675059
Support Through Remote Observation and Nutrition Guidance (STRONG) Program for Pancreatic…
Trial completed
2026-07-31 NCT07686250
Evaluation and Outcomes of SAVI Scout MD for Localized Breast Surgery
Recruitment opened
2026-07-31 NCT04996823
Axitinib + Ipilimumab in Advanced Melanoma
Enrollment closed, study ongoing
2026-07-31 NCT04335799
Reducing Weight and Elevated Stress Levels Using Educational and Behavioral Tools
date change Primary completion moved earlier: 2026-04-14 -> 2025-12-19
2026-07-31 NCT06963346
Study Investigating Intravesical HDAC Inhibition to Improve Response to Immuno-Oncology…
Recruitment resumed after suspension
2026-07-31 NCT05438940
Support Through Remote Observation and Nutrition Guidance (STRONG) Program for…
Trial completed
2026-07-31 NCT05438940
Support Through Remote Observation and Nutrition Guidance (STRONG) Program for…
date change Completion moved earlier: 2026-06 -> 2025-06-12
2026-07-31 NCT03628209
Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma
date change Completion pushed: 2026-04 -> 2027-04
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-08-10 NCT07754448 Libre Del Cigarrillo: Development of an mHealth Smoking Cessation App to Extend Reach of… Not Yet Recruiting
2026-07-24 NCT07725380 Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma Phase 1/2 Recruiting
Active Trials by Phase
Phase 3
1
Phase 2/3
1
Phase 2
55
Phase 1/2
10
Phase 1
25
Early Phase 1
9
Not specified
43
Active Trials — top 25 of 144
NCT IDTitleConditionStatus
Phase 3
NCT07357298 Phase III Trial of Brain MRI Surveillance in Stage IV Breast Cancer Breast Cancer Recruiting
Phase 2/3
NCT03495427 PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher… Prostate Cancer Recruiting
Phase 2
NCT06597565 A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC Head and Neck Squamous Cell Carcinoma Recruiting
NCT06947083 Elranatamab Post Cilta-cel in Patients With Clinical High Risk Relapsed Myeloma Myeloma Recruiting
NCT05301283 Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue… High Grade Sarcoma Recruiting
NCT05526989 Study of the Combination Dostarlimab With Niraparib In Patients With Penile Carcinoma Penile Carcinoma Recruiting
NCT06121180 Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma Metastatic Uveal Melanoma Recruiting
NCT06409390 Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer Metastatic Breast Cancer Recruiting
NCT06350318 Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas Follicular Lymphoma Recruiting
NCT05528133 Genomically Guided Radiation Therapy in the Management of Triple Negative Breast Cancer Triple Negative Breast Cancer Recruiting
NCT06088498 App for Reducing Cravings to Smoke Smoking Recruiting
NCT06511882 Discontinuation of Hypomethylating Agent and Venetoclax in Patients With AML MRD Acute Myeloid Leukemia Recruiting
NCT05325632 Study of HER2 Directed Dendritic Cell (DC1) Vaccine + Weekly Paclitaxel, Trastuzumab &… HER2-positive Breast Cancer Recruiting
NCT05757219 Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy Diffuse Large B Cell Lymphoma Recruiting
NCT06104592 Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk… Large B-cell Lymphoma Recruiting
NCT06144606 Study of KTE-X19 in Minimal Residual Disease (MRD) Positive B-Cell Acute Lymphoblastic… B-Cell Lymphoblastic Leukemia Recruiting
NCT06553872 Phase 2 Open Label Randomized Study of Pirtobrutinib and Brexucabtagene Autoleucel in R/R… Mantle Cell Lymphoma Recruiting
NCT07276386 Phase 2 Combination of Melphalan/HDS Via PHP + Tebentafusp in Treating Metastatic Uveal… Metastatic Uveal Melanoma Recruiting
NCT04562129 IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients Melanoma Stage III Recruiting
NCT06137274 Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC Squamous Cell Carcinoma Recruiting
NCT06295159 Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma Melanoma Stage III Recruiting
NCT06553885 Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC Metastatic Colorectal Cancer Recruiting
NCT06660368 BCL2i CLAG-M in R/R Acute Myeloid Leukemia Relapsed or Refractory Acute Myeloid Leukemia (AML) Recruiting
NCT07007273 Pembrolizumab for Advanced Cutaneous Sarcomas Not Including Angiosarcoma Cutaneous Sarcoma Recruiting
NCT06760156 Tafasitamab and Lenalidomide as First Salvage Therapy for Residual Large B Cell Lym Large B-cell Lymphoma Recruiting
See all 144 active H. Lee Moffitt Cancer Center and Research Institute trials with filters →
Disease Areas
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