Sponsor pipeline

Bristol-Myers Squibb clinical trial pipeline

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228 active trials 116 recruiting 73 Phase 3 10 disease areas 60 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 35 of 60 changes on 19 trials

2026-08-27
Primary endpoint(s) modified
NCT05625399 A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously… · Phase 3
2026-08-11
Primary endpoint(s) modified
Enrollment increased: 500 → 600 participants
NCT06926868 A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously… · Phase 2/3
2026-08-18
Primary endpoint(s) modified
Enrollment increased: 72 → 236 participants
Trial arms changed: 3 → 6
NCT07063342 A Study to Evaluate Novel KarX and KarT Prototypes Versus the KarXT and KarX-EC Reference… · Phase 1
2026-08-26
Trial completed
NCT04039607 A Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced… · Phase 3
2026-08-25
Trial completed
Completion pushed: 2026-01-16 → 2026-04-01
NCT03141177 A Study of Nivolumab Combined With Cabozantinib Compared to Sunitinib in Previously… · Phase 3
2026-08-25
Recruitment opened
Trial sites reduced: 43 → 39 locations
NCT07412704 A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis · Phase 1/2
2026-08-04
Trial status changed: Recruiting → Not Yet Recruiting
NCT07335562 A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel /… · Phase 3
2026-07-31
Trial completed
Completion moved earlier: 2027-05-27 → 2026-05-19
NCT02632409 An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients… · Phase 3
2026-08-04
Enrollment closed, study ongoing
NCT07015983 A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in… · Phase 2
2026-07-31
Enrollment closed, study ongoing
Trial sites reduced: 117 → 86 locations
NCT06122779 Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in… · Phase 2
2026-07-31
Recruitment opened
Trial sites reduced: 60 → 57 locations
NCT07492680 A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants… · Phase 2
2026-08-04
Enrollment closed, study ongoing
NCT06220201 A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in… · Phase 1
2026-08-04
Enrollment closed, study ongoing
Trial sites reduced: 54 → 46 locations
NCT05869955 A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe… · Phase 1
2026-08-04
Trial completed
NCT07422298 A Study to Evaluate the Effect of BMS-986278 on Cardiac Repolarization in Healthy… · Phase 1
2026-08-05
Trial completed
Enrollment increased: 55 → 650 participants
Primary completion moved earlier: 2026-06-30 → 2025-10-31
Completion moved earlier: 2026-06-30 → 2025-10-31
NCT06448793 Patient and Physician Preference Study in Resectable, Non-small Cell Lung Cancer…
2026-08-04
Primary completion pushed: 2029-07-05 → 2029-08-06
Trial sites reduced: 40 → 35 locations
Completion pushed: 2029-07-05 → 2029-08-06
NCT07284745 A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With… · Phase 3
2026-08-01
Primary completion pushed: 2026-02-27 → 2026-05-27
Completion pushed: 2031-02-27 → 2031-05-27
NCT03383458 A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk… · Phase 3
2026-08-25
Trial sites expanded: 200 → 208 locations
NCT07680790 Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus… · Phase 3
2026-08-25
Trial sites expanded: 54 → 63 locations
NCT07285798 A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With… · Phase 3
2026-08-25
Trial sites expanded: 35 → 39 locations
NCT07284745 A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With… · Phase 3

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-08-27 NCT07791199 Continued Access to Deucravacitinib for Adult SLE/SjD and Pediatric PsO/PsA Study… Phase 3 Not Yet Recruiting
2026-08-24 NCT07783373 Long-Term Real-World Safety of Cobenfy in Adults With Schizophrenia Active, Not Recruiting
2026-08-21 NCT07780383 A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and… Phase 1 Not Yet Recruiting
2026-08-20 NCT07777120 Liso-Cel in Relapsed/Refractory Marginal Zone Lymphoma Active, Not Recruiting
2026-08-20 NCT07777133 A Study to Evaluate the Metabolism, the Routes and Extent of Elimination, and Drug Levels… Phase 1 Not Yet Recruiting
2026-08-19 NCT07772531 A Study to Evaluate BMS-986511 in Adults With Major Depressive Disorder Phase 2 Not Yet Recruiting
2026-08-13 NCT07763418 A Study to Evaluate the Pharmacokinetics and Safety of Golcadomide in Participants With… Phase 1 Not Yet Recruiting
2026-08-10 NCT07755826 Repotrectinib Post-Marketing Surveillance in Pediatric Patients With NTRK Fusion-Positive… Recruiting
2026-08-07 NCT07752121 First-Line Luspatercept in Transfusion-Dependent Lower-Risk Myelodysplastic Neoplasms Not Yet Recruiting
2026-07-29 NCT07732907 Risk of Progressive Multifocal Leukoencephalopathy Among Patients With Multiple Sclerosis… Recruiting

Active trials by phase

Phase 1
31
Phase 1/2
23
Phase 2
23
Phase 2/3
11
Phase 3
62
Phase 4
7
Not charted: 71 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 228

NCT IDTitleConditionStatusUpdated
Phase 4
NCT07221877 A Study to Evaluate the Effect of KarXT on Urological Safety Schizophrenia Recruiting 2026-06-03
NCT06875960 A Study to Continue the Administration of Deucravacitinib in Participants With Systemic… Systemic Lupus Erythematosus (SLE) Recruiting 2026-03-30
NCT07459543 A Study to Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose… Unresectable Melanoma Not Yet Recruiting 2026-08-12
NCT06112743 A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With… Cardiomyopathy, Hypertrophic Active, Not Recruiting 2026-08-06
NCT07004972 A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India… Symptomatic Obstructive Hypertrophic Cardiomyopathy Active, Not Recruiting 2026-04-28
NCT05891249 A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of… Anemia Active, Not Recruiting 2025-10-20
NCT06396039 A Study to Assess the Effectiveness and Safety of Ozanimod in Chinese Adults With… Relapsing Multiple Sclerosis Active, Not Recruiting 2025-04-16
Phase 3
NCT07011745 A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment… Alzheimer's Disease Recruiting 2026-08-26
NCT06929273 A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in… Bipolar Disorder Type I With Mania Recruiting 2026-08-25
NCT05519085 A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus… Relapsed or Refractory Multiple Myeloma Recruiting 2026-08-21
NCT07116967 Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With… Plaque Psoriasis Recruiting 2026-08-21
NCT06976216 A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment… Alzheimer's Disease Recruiting 2026-08-20
NCT06869551 A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165)… Juvenile Psoriatic Arthritis Recruiting 2026-08-19
NCT06937229 A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in… Alzheimer Disease Recruiting 2026-08-19
NCT04772079 A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children… Plaque Psoriasis Recruiting 2026-08-18
NCT06615479 A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in… Relapsed or Refractory Multiple Myeloma (RRMM) Recruiting 2026-08-18
NCT06764485 A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice… Metastatic Castration-resistant Prostate Cancer Recruiting 2026-08-18
NCT06951711 A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes… Bipolar Disorder Type I With Mania or Mania With Mixed Features Recruiting 2026-08-18
NCT06561386 A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs… Non-small Cell Lung Cancer Recruiting 2026-08-17
NCT06646276 A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed… Extensive-Stage Small Cell Lung Cancer Recruiting 2026-08-14
NCT07288567 A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia… Schizophrenia Recruiting 2026-08-13
NCT06976203 A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment… Alzheimer's Disease Recruiting 2026-08-12
NCT06979453 A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165)… Plaque Psoriasis Recruiting 2026-08-11
NCT07011732 A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment… Alzheimer Disease Recruiting 2026-08-11
NCT07361497 A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation… Non-small Cell Lung Cancer (NSCLC) Recruiting 2026-08-10
See all 228 active Bristol-Myers Squibb trials with filters →

Disease areas by active trials

Non-Small Cell Lung Cancer (NSCLC) (23) · Lung Cancer (23) · Multiple Myeloma (17) · Psoriasis (15) · Myelodysplastic Syndromes (MDS) (11) · Leukemia (9) · Multiple Sclerosis (9) · Alzheimer's Disease (9) · Melanoma (8) · Lupus (SLE) (8)

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