Disease landscape

Psoriasis clinical trials

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298 active trials 148 recruiting 49 Phase 3 179 sponsors 34 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 29 of 34 changes on 20 trials

2026-08-11
Trial terminated
Trial terminated: Sponsor decision
Enrollment reduced: 250 → 65 participants
Primary completion moved earlier: 2026-02-28 → 2025-12-16
Completion moved earlier: 2026-03 → 2025-12-16
NCT06380907 A Phase 2 Study of ZL-1102 in Patients With Chronic Plaque Psoriasis · Zai Lab (Hong Kong), Ltd. · Phase 2
2026-09-05
Primary completion pushed: 2026-07-01 → 2027-01-01
Completion pushed: 2026-07-01 → 2027-01-01
NCT06399432 Mediterranean Diet vs no Dietary Intervention for Improving Signs and Symptoms of… · University Hospitals Cleveland Medical Center
2026-08-22
Primary completion pushed: 2026-08-28 → 2026-12-31
NCT06382051 Modifying PEST for Psoriatic Arthritis Screening · Novartis Pharmaceuticals
2026-09-01
Primary completion pushed: 2026-08-17 → 2027-02-17
Completion pushed: 2026-08-18 → 2027-02-18
NCT05307809 Cytokine Expression in Psoriasis Patients With and Without Joint Involvement · Poitiers University Hospital
2026-08-29
Trial completed
Primary completion confirmed: August 2026 (last estimated October 2026)
NCT07357831 A Phase III Trial To Evaluate The Efficacy And Safety Of MC2-01 Cream Compared To CAL/BDP… · Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. · Phase 3
2026-08-29
Trial completed
NCT06088199 A Study of Apremilast in Pediatric Participants in Children With Mild to Moderate Plaque… · Amgen · Phase 3
2026-08-29
Recruitment opened
NCT07654751 A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are… · Janssen Research & Development, LLC · Phase 4
2026-08-08
Enrollment closed, study ongoing
Trial sites reduced: 50 → 42 locations
NCT06425549 A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in… · UCB Biopharma SRL · Phase 3
2026-08-21
Recruitment opened
NCT07719530 Phase II Clinical Trial of SHR-1139 Injection in Patients With Psoriasis · Guangdong Hengrui Pharmaceutical Co., Ltd · Phase 2
2026-08-18
Enrollment closed, study ongoing
NCT07290569 Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis · Oruka Therapeutics, Inc. · Phase 2
2026-08-28
Trial status changed: Enrolling by Invitation → Recruiting
NCT02707341 The CorEvitas Psoriasis (PSO) Registry · CorEvitas
2026-08-09
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT07532486 A Study to Evaluate Comparative Efficacy and Safety of Guselkumab in High-dose and… · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-08-09
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT06811558 Ixekizumab Versus Secukizumab in Over 70-year-old Patients with Psoriasis · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-08-09
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT06794671 A Basket Trial of Vunakizumab in Inflammatory Skin Diseases · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-08-09
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT05503875 Immunoclassification of Psoriasis: a Strategy for Precision Medicine · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-08-09
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT04465838 Chinese Psoriasis Real World Evidence Research · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-09-05
Trial sites expanded: 26 → 32 locations
NCT07449702 An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis · Oruka Therapeutics, Inc. · Phase 2
2026-08-29
Enrollment increased: 15849 → 20167 participants
NCT00508547 Psoriasis Longitudinal Assessment and Registry · Janssen Scientific Affairs, LLC
2026-08-07
Primary completion pushed: 2026-06 → 2026-09
Completion pushed: 2026-07 → 2026-10
NCT05908240 Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or… · University of Pennsylvania
2026-08-22
Trial sites expanded: 394 → 402 locations
NCT07116967 Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With… · Bristol-Myers Squibb · Phase 3

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-04 NCT07804134 Skin-in-Sight: a Longitudinal Cohort Infrastructure for Standardized Remote Monitoring… Medisch Spectrum Twente new
2026-09-03 NCT07802964 A Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity… Fujian Shengdi Pharmaceutical Co., Ltd. new Phase 1
2026-08-28 NCT07792928 A Phase 1 Study to Evaluate the Safety and Effects of a Single Dose of HCXT-2001 Tablets… Shanghai Peptidstar Therapeutics Limited new Phase 1
2026-08-05 NCT07746479 A Study to Evaluate the Efficacy and Safety of LZM012 ( Psoriasis ) Livzon Pharmaceutical Group Inc. new Phase 3
2026-08-05 NCT07746583 A Study of Guselkumab Given After Ustekinumab in Participants With Moderate to Severe… Janssen-Cilag Kft. new
2026-07-30 NCT07736651 Anti Inflammatory Diet With Physical Therapy on Psoriasis Mahmoud Usama Mahmoud Ahmed new
2026-07-30 NCT07736586 A Study of HL40626S Tablets in Healthy Adults Highslab Therapeutics, Inc. new Phase 1
2026-07-29 NCT07733089 A Trial to Understand How Safe and Well Tolerated ZP9830 is and How it Works in People… Zealand Pharma new Phase 1
2026-07-28 NCT07730619 To Explore the Influencing Factors and Solutions for Patients With Plaque Psoriasis… First Affiliated Hospital Xi'an Jiaotong University new
2026-07-24 NCT07725822 An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic… Modern Research Associates, PLLC new Phase 4

Active trials by phase

Early Phase 1
5
Phase 1
19
Phase 1/2
4
Phase 2
29
Phase 2/3
5
Phase 3
44
Phase 4
36
Not charted: 156 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 298

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT06857942 A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation… Eli Lilly and Company Recruiting 2026-09-04
NCT07654751 A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are… Janssen Research & Development, LLC Recruiting 2026-08-28
NCT05390515 Psoriatic Immune Response to Tildrakizumab University of California, San Francisco Recruiting 2026-06-04
NCT05858632 Immune Spatial Features of Guselkumab Cutaneous Response University of California, San Francisco Recruiting 2026-06-04
NCT05858645 Correction of Psoriatic T Cell Signatures by Deucravacitinib University of California, San Francisco Recruiting 2026-06-04
NCT07432815 Treatment of Psoriasis With Depression and/or Anxiety With Methotrexate vs Combined… Cairo University Recruiting 2026-05-05
NCT05270733 Development of Predictive Psoriasis Response Endotypes Using Single Cell Transcriptomics University Hospitals Cleveland Medical Center Recruiting 2026-04-02
NCT05004727 Multi-Center PAMPA Study NYU Langone Health Recruiting 2026-03-30
NCT06398106 Proactive TDM Versus Standard Use of Biologics in Psoriasis University Hospital, Ghent Recruiting 2026-03-04
NCT07401992 Effects of Semaglutide on Clinical Outcomes and Metabolic Inflammation in Psoriasis Hospital Universitario Dr. Jose E. Gonzalez Recruiting 2026-02-11
NCT07149792 A Multi-center RCT Clinical Trial on Personalized Precision Medicine for Patients With… Taichung Veterans General Hospital Recruiting 2025-09-02
NCT03987763 A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With… Bausch Health Americas, Inc. Recruiting 2025-08-27
NCT06974474 Potential Role of Guselkumab in Modulating PAIN Perception and Related Gene Pathways: a… Fondazione Policlinico Universitario Campus Bio-Medico Recruiting 2025-05-16
NCT04537689 Outcomes With Treatment and Withdraw of Ixekizumab in Patients With Plaque Psoriasis Singapore General Hospital Recruiting 2022-11-25
NCT04372277 Taltz in Combination With Enstilar for Psoriasis Psoriasis Treatment Center of Central New Jersey Recruiting 2020-05-04
NCT04119102 Duobrii in Combination With Biologics Psoriasis Treatment Center of Central New Jersey Recruiting 2020-04-30
NCT04347473 ILUMYA in Combination With HALOG Ointment 0.1% for Plaque Psoriasis. Psoriasis Treatment Center of Central New Jersey Recruiting 2020-04-15
NCT03827876 Enstilar in Combination With Enbrel or Humira for Plaque Psoriasis Psoriasis Treatment Center of Central New Jersey Recruiting 2019-02-04
NCT06013969 A Study to Test Whether Spesolimab Helps People With Generalized Pustular Psoriasis (GPP)… LEO Pharma Active, Not Recruiting 2026-09-02
NCT07744191 A Clinical Trial of Antiplatelets in Psoriasis NYU Langone Health Not Yet Recruiting 2026-08-05
NCT07725822 An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic… Modern Research Associates, PLLC Not Yet Recruiting 2026-07-28
NCT07713212 Combined Fractional CO₂ Laser and Topical Corticosteroid Versus Topical Corticosteroid… Cairo University Not Yet Recruiting 2026-07-20
NCT07487831 The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease University of California, San Francisco Not Yet Recruiting 2026-06-09
NCT07635043 Efficacy of Topical Tapinarof Versus Betamethasone in the Treatment of Plaque Psoriasis Pakistan Institute of Medical Sciences Not Yet Recruiting 2026-06-09
NCT07352566 Utilization of a Microdevice for Psoriasis and Atopic Dermatitis University of California, San Francisco Not Yet Recruiting 2026-06-03
See all 298 active Psoriasis trials with filters →

Top sponsors by active trials in this area

Bristol-Myers Squibb (15) · Janssen Research & Development, LLC (8) · Cairo University (6) · University of California, San Francisco (6) · AbbVie (5) · Assiut University (5) · Psoriasis Treatment Center of Central New Jersey (5) · Second Affiliated Hospital, School of Medicine, Zhejiang University (5) · Assistance Publique - Hôpitaux de Paris (4) · Bausch Health Americas, Inc. (4)

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