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Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Study acronym: IZAR-2
StatusActive, Not Recruiting
PhasePhase 3
Started
View on ClinicalTrials.gov ↗

Record History

  1. Minor Enrollment closed, study ongoing Completion pushed from Jan 15, 2027 to Sep 13, 2027 · Primary completion date: Jan 15, 2027 to Jan 4, 2027 · Eligibility criteria expanded, about 14 words · 1 more Show 4 more changesShow less
    • Completion pushed from Jan 15, 2027 to Sep 13, 2027
    • Primary completion date: Jan 15, 2027 to Jan 4, 2027
    • Eligibility criteria expanded, about 14 words
    • Site details revised at 143 of 143 sites
  2. Minor Study sites: 142 to 143v14
  3. Minor Trial sites expanded: 139 → 142 locationsv13
  4. Minor Study sites: 138 to 139v12
  5. Minor Study sites: 136 to 138v11
  6. Minor Study sites: 135 to 136v10
  7. Minor Trial sites expanded: 128 → 135 locationsv9
  8. Minor Study sites: 126 to 128v8
  9. Minor Study sites: 123 to 126v7
  10. Minor Study sites: 121 to 123 Eligibility criteria expanded, about 5 wordsv6 Show 1 more changeShow less
    • Eligibility criteria expanded, about 5 words

    See this version in full on ClinicalTrials.gov ↗

  11. Minor Study sites: 115 to 121v5
  12. Minor Study sites: 9 to 115v4
  13. Minor Study sites: 3 to 9v3
  14. Notable Trial status: Not Yet Recruiting to Recruiting Study sites: 0 to 3v2 Show 1 more changeShow less
    • Study sites: 0 to 3
  15. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This is a study to confirm the clinical efficacy and safety of sonelokimab compared with placebo in the treatment of adults with active psoriatic arthritis who have had a previous inadequate response or intolerance to anti-tumor necrosis factor (TNF)α therapy.
Trial Details
NCT Number NCT06641089
Lead Sponsor MoonLake Immunotherapeutics AG
Conditions Arthritis, Psoriatic
Enrollment 600 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov