Disease landscape

Gastric Cancer clinical trials

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948 active trials 531 recruiting 94 Phase 3 456 sponsors 101 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 45 of 101 changes on 20 trials

2026-08-14
Trial terminated
Trial terminated: Following completion of Phase 1b, the Sponsor decided not to initiate Part 2 of the trial.
Primary endpoint(s) modified
Primary completion moved earlier: 2025-07 → 2025-04-30
Completion moved earlier: 2025-11 → 2025-04-30
NCT05572684 A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants… · NextCure, Inc. · Phase 1/2
2026-08-22
Recruitment suspended
Recruitment suspended: Gilead's ongoing evaluation of the wider Zimberelimab and Domvanalimab programme, following the outcomes of the ST...
NCT06250036 Zimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer · Royal Marsden NHS Foundation Trust · Phase 2
2026-09-04
Primary completion pushed: 2025-11-28 → 2027-02-10
NCT06271837 A Study of T-DXd as Monotherapy or in Combination With Anti-cancer Agents in Patients… · AstraZeneca · Phase 2
2026-09-04
Primary completion pushed: 2026-04 → 2026-12
Enrollment closed, study ongoing
Completion pushed: 2026-04 → 2026-12
NCT06337084 Diagnostic Efficacy and Dosimetry of MNPR-101-DFO*-89Zr in Patients With Solid Tumors · Monopar Therapeutics · Phase 1
2026-09-01
Primary completion pushed: 2026-12-31 → 2027-06-30
Completion pushed: 2027-11-30 → 2028-05-31
NCT03505320 A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer · Astellas Pharma Global Development, Inc. · Phase 2
2026-09-04
Primary completion pushed: 2026-08-11 → 2027-08-11
Completion pushed: 2026-12-10 → 2027-12-10
NCT04069273 Novel SEQUEnced Immunotherapy With Anti-angiogenesis and Chemotherapy in Advanced… · Harry H Yoon · Phase 2
2026-08-12
Primary completion pushed: 2025-06-30 → 2026-12-30
Sponsor changed: Evopoint Biosciences Inc. → Astellas Pharma Global Development, Inc.
Enrollment closed, study ongoing
Completion pushed: 2025-12-31 → 2027-06-30
NCT06792435 XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies. · Astellas Pharma Global Development, Inc. · Phase 1/2
2026-09-03
Primary completion pushed: 2031-06 → 2031-11
Phase changed: Phase 2/3 → Phase 2
Trial sites expanded: 2 → 5 locations
NCT07000253 Timing of Minimally Invasive Local Treatment After First-Line Systemic Therapy in… · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Phase 2
2026-09-03
Primary endpoint(s) modified
Trial completed
Primary completion confirmed: June 2026 (last estimated June 2027)
NCT05864144 A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in… · Sensei Biotherapeutics, Inc. · Phase 1/2
2026-08-26
Primary completion pushed: 2026-09-01 → 2028-09-01
Completion pushed: 2028-12-31 → 2030-12-31
NCT05483491 KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer · Christian Hinrichs · Phase 1
2026-08-19
Primary completion pushed: 2026-08-01 → 2028-08-01
Primary endpoint(s) modified
Phase changed: Phase 2/3 → Phase 2
Completion pushed: 2028-08-01 → 2029-08-01
NCT06826079 Safety and Efficacy Study of Sorbitol With Neoadjuvant Chemotherapy Combined With… · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Phase 2
2026-08-19
Primary completion pushed: 2026-06 → 2027-07
NCT07025889 IBI343 Combined With Sintilimab Plus Chemotherapy in Gastric Cancer · Ruijin Hospital · Phase 1/2
2026-08-07
Primary completion pushed: 2030-12-31 → 2031-04-30
Completion pushed: 2030-12-31 → 2031-04-30
NCT07101666 Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer · Washington University School of Medicine · Phase 2
2026-08-20
Primary completion pushed: 2026-06-15 → 2026-10-01
Completion pushed: 2026-06-15 → 2026-10-01
NCT05203627 Telehealth for the Self-Management of Dietary Quality of Life in Patients After Stomach… · City of Hope Medical Center
2026-08-15
Primary completion pushed: 2026-06-30 → 2027-04-30
NCT04221893 Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers · University of California, San Francisco
2026-08-26
Primary endpoint(s) modified
NCT07781852 Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and… · Lumina Pharmaceuticals Inc · Early Phase 1
2026-08-21
Primary endpoint(s) modified
Trial arms changed: 4 → 5
NCT05269381 Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for… · Mayo Clinic · Phase 1/2
2026-08-22
Primary endpoint(s) modified
NCT06788548 Fluorescence Guided Laparoscopic-Endoscopic Cooperative Sentinel Lymph Node Navigation… · Beijing Friendship Hospital
2026-08-07
Enrollment reduced: 450 → 165 participants
Enrollment closed, study ongoing
Trial sites reduced: 41 → 36 locations
NCT05581004 A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single… · Genentech, Inc. · Phase 1
2026-09-04
Enrollment closed, study ongoing
NCT06617169 Dose-Escalation of MNPR-101-PCTA-177Lu in Solid Tumors · Monopar Therapeutics · Phase 1

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-03 NCT07803159 Frailty, Immunonutrition, Surgery Type, and Biologic Recovery in Elderly Gastric Cancer Kocaeli City Hospital new
2026-08-28 NCT07793318 TR115 in ARID1A-Mutated Advanced Solid Tumors Tarapeutics Science Inc. new Phase 2
2026-08-27 NCT07789184 Radical Surgery Versus Non-Surgery in Gastric Cancer Patients With Peritoneal Metastasis… Hua Huang, MD, PhD new Phase 3
2026-08-24 NCT07781852 Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and… Lumina Pharmaceuticals Inc new Early Phase 1
2026-08-24 NCT07782294 AI-Assisted Novel rbcDNA Detection for Early Gastric Cancer Diagnosis Second Affiliated Hospital, Zhejiang University, School of Medicine new
2026-08-24 NCT07781319 Early Gastric Cancer in the Spanish EURECCA Registry Corporacion Parc Tauli new
2026-08-19 NCT07772453 Ferric Carboxymaltose Versus Iron Sucrose for Iron Deficiency Anemia After Radical… Zhaojian Niu,MD new Phase 4
2026-08-18 NCT07770100 Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy… Mark Bernard new Phase 2
2026-08-18 NCT07770126 The Prevalence and the Pathophysiological Role of Non-Helicobacter Pylori Helicobacter… Universiteit Antwerpen new
2026-07-29 NCT07732543 Developing and Testing the Effectiveness of Smart Healthcare Assisted Individualized… Taipei Veterans General Hospital, Taiwan new

Active trials by phase

Early Phase 1
15
Phase 1
106
Phase 1/2
79
Phase 2
247
Phase 2/3
21
Phase 3
73
Phase 4
15
Not charted: 392 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 948

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT05183126 Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With… University of Michigan Rogel Cancer Center Recruiting 2026-07-02
NCT07139366 Saccharomyces Boulardii Combined With Bismuth Quadruple Therapy for Helicobacter Pylori… Yongquan Shi Recruiting 2025-12-02
NCT07124351 Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™) Cedars-Sinai Medical Center Recruiting 2025-09-15
NCT07068607 Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for… Yongquan Shi Recruiting 2025-08-14
NCT02047994 Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for… International Agency for Research on Cancer Recruiting 2025-05-02
NCT07801027 A Trial of Pembrolizumab With Chemotherapy or Chemoradiotherapy in Participants From… Merck Sharp & Dohme LLC Not Yet Recruiting 2026-09-03
NCT07772453 Ferric Carboxymaltose Versus Iron Sucrose for Iron Deficiency Anemia After Radical… Zhaojian Niu,MD Not Yet Recruiting 2026-08-19
NCT07502027 A Clinical Study of Iparomlimab and Tuvonralimab Combined With SOX Following… Huazhong University of Science and Technology Not Yet Recruiting 2026-03-30
NCT07312370 Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing LanZhou University Not Yet Recruiting 2026-03-23
NCT07467174 RCT Comparing Reduced-port Robotic and Conventional Laparoscopic Subtotal Gastrectomy Yonsei University Not Yet Recruiting 2026-03-12
NCT07224035 Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community- AIM 1 University of Miami Active, Not Recruiting 2026-02-17
NCT07224048 Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community-AIM 2 University of Miami Active, Not Recruiting 2026-02-17
NCT06499610 Clinical Study of Irinotecan Liposome Combination Therapy for Advanced Gastric Cancer First Affiliated Hospital Xi'an Jiaotong University Not Yet Recruiting 2024-07-12
NCT05498766 Effect and Safety of Huaier Granule Versus SOX Regimen in Gastric Cancer Patients Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Not Yet Recruiting 2024-06-24
NCT04168346 Preoperative Intravenous Iron Therapy in Patients With Gastric Cancer Helsinki University Central Hospital Not Yet Recruiting 2019-11-19
Phase 3
NCT05677490 mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced… Alliance for Clinical Trials in Oncology Recruiting 2026-09-03
NCT07673887 A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric… Astellas Pharma Global Development, Inc. Recruiting 2026-09-02
NCT07043400 A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus… BeOne Medicines Recruiting 2026-08-24
NCT06731478 Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic… Daiichi Sankyo Recruiting 2026-08-10
NCT06901531 A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With… Astellas Pharma Global Development, Inc. Recruiting 2026-07-31
NCT07518147 A Study Comparing BL-M05D1 With the Investigator's Choice of Treatment Regimen in… Sichuan Baili Pharmaceutical Co., Ltd. Recruiting 2026-07-08
NCT07304271 Intraperitoneal Paclitaxel and Systemic Therapy Versus Systemic Therapy Alone in Gastric… Magnus Nilsson Recruiting 2026-07-07
NCT07431281 Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in… AstraZeneca Recruiting 2026-07-01
NCT07217704 Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or… SOFIE Recruiting 2026-06-30
NCT07584135 JS107 in Combination With Toripalimab and Chemotherapy for the Treatment of… NingBo Junyan Hongshi Biosciences Co., Ltd Recruiting 2026-06-29
See all 948 active Gastric Cancer trials with filters →

Top sponsors by active trials in this area

The First Affiliated Hospital with Nanjing Medical University (24) · Fudan University (23) · AstraZeneca (17) · National Cancer Institute (NCI) (17) · Fujian Medical University (15) · Nanfang Hospital, Southern Medical University (13) · Qilu Hospital of Shandong University (12) · Tianjin Medical University Cancer Institute and Hospital (12) · Memorial Sloan Kettering Cancer Center (11) · Ruijin Hospital (11)

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