Disease landscape

Obesity clinical trials

Get alerts when Obesity trials change

2,482 active trials 1,275 recruiting 153 Phase 3 1,142 sponsors 386 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 52 of 386 changes on 20 trials

2026-08-08
Trial status changed: Suspended → Withdrawn
NCT07252037 Dietary Guidelines for Americans-Ultra Processed Study · USDA Grand Forks Human Nutrition Research Center
2026-08-08
Trial terminated
Trial terminated: Reprioritization of research efforts
Enrollment reduced: 10 → 1 participants
Primary completion moved earlier: 2027-11 → 2026-06-10
Completion moved earlier: 2028-01 → 2026-06-10
NCT06606327 Diazoxide Suppression Test P&F Study · Columbia University · Phase 1
2026-09-04
Primary completion pushed: 2027-01-17 → 2027-06-21
Enrollment increased: 35 → 70 participants
Completion pushed: 2027-01-17 → 2027-06-21
NCT07754474 A Study to Test How Well Different and Multiple Doses of BI 3034701 Are Tolerated in… · Boehringer Ingelheim · Phase 1
2026-09-03
Primary completion pushed: 2026-08 → 2026-12
Enrollment increased: 78 → 114 participants
Interventions modified
Completion pushed: 2026-08 → 2026-12
Trial arms changed: 11 → 13
NCT07463196 A Study Investigating the Safety, Absorption, Elimination, and the Effect on the Immune… · AC Immune SA · Phase 1
2026-09-03
Primary completion pushed: 2026-04-30 → 2027-07-31
Completion pushed: 2026-04-30 → 2027-09-30
NCT06728800 Leveraging Interactive Digital Technology to Increase Access to Family-Based Behavioral… · 3-C Institute for Social Development
2026-08-29
Primary completion pushed: 2026-08-03 → 2027-01-05
Completion pushed: 2026-11-22 → 2027-04-28
NCT07243171 A Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and… · Hangzhou Sciwind Biosciences Co., Ltd. · Phase 1/2
2026-08-26
Primary completion pushed: 2026-03-26 → 2026-07-20
Trial completed
Completion pushed: 2026-05-17 → 2026-07-20
NCT06719011 A Study on How NNC0174-1213 Works in People With Overweight or Obesity. · Novo Nordisk A/S · Phase 1
2026-09-04
Primary completion pushed: 2026-08-31 → 2026-12-31
Completion pushed: 2026-08-31 → 2026-12-31
NCT04838678 Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN) · University of Texas Southwestern Medical Center · Early Phase 1
2026-08-22
Primary completion pushed: 2026-02 → 2026-09
Enrollment closed, study ongoing
Completion pushed: 2026-06 → 2027-01
NCT05822544 Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or… · OrsoBio, Inc · Phase 1
2026-08-18
Primary completion pushed: 2026-09-24 → 2027-10-11
Trial sites expanded: 1 → 4 locations
Completion pushed: 2026-09-24 → 2027-10-11
NCT06577766 A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With… · Novo Nordisk A/S · Phase 1
2026-08-08
Primary completion pushed: 2026-10 → 2027-03
Enrollment increased: 48 → 80 participants
Completion pushed: 2026-10 → 2027-03
Trial arms changed: 4 → 8
NCT07291232 A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics… · AbbVie · Phase 1
2026-09-01
Primary completion pushed: 2026-08 → 2027-01
Completion pushed: 2026-08 → 2027-01
NCT05051436 The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics · Philip Kern · Phase 4
2026-09-04
Primary completion pushed: 2026-07-08 → 2026-12-08
Completion pushed: 2026-07-08 → 2026-12-08
NCT06137261 Screening Adults With Obesity to Reduce Heart Failure Events · Franciscus Gasthuis
2026-09-04
Primary completion pushed: 2026-05-30 → 2028-09-30
Completion pushed: 2026-05-31 → 2028-12-31
NCT05987410 EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight… · Fondazione Don Carlo Gnocchi ETS
2026-09-04
Primary completion pushed: 2026-07-30 → 2026-10-30
NCT06115265 Ketogenic Diet and Diabetes Demonstration Project · University of New Mexico
2026-08-15
Primary completion pushed: 2025-11 → 2026-03-01
Trial completed
Completion pushed: 2025-12 → 2026-03-01
NCT06911073 A Study to Evaluate a Postbiotic in Supporting Weight Loss and Metabolic Health · ResBiotic Nutrition, Inc.
2026-09-03
Primary completion pushed: 2026-08-31 → 2026-12-31
Completion pushed: 2026-08-31 → 2026-12-31
NCT05028309 Effects of Obesity in the Aged · University of Texas Southwestern Medical Center
2026-09-03
Primary completion pushed: 2026-06-01 → 2027-06-01
Completion pushed: 2026-06-01 → 2027-09-01
NCT06735651 Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes · Georgia State University
2026-09-03
Primary completion pushed: 2027-02-02 → 2027-10-02
Completion pushed: 2027-06-30 → 2027-10-30
NCT07344324 Study Evaluating the Safety and Feasibility of Endoscopic Duodenal Injections of… · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
2026-09-02
Primary completion pushed: 2026-01-01 → 2027-03-01
Enrollment closed, study ongoing
Completion pushed: 2026-09-30 → 2027-08-31
NCT05468437 Telenutrition for Individuals With SCI · Santa Clara Valley Health & Hospital System

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-04 NCT07804290 Quality of Recovery and Patient Satisfaction After Metabolic Surgery at a Tertiary… Sefako Makgatho Health Sciences University new
2026-09-03 NCT07802080 Effects of Kettlebell Swing Training Combined With Breathing Exercises on Respiratory… University of Phayao new
2026-09-03 NCT07802275 Postprandial Glucose Kinetics After Carbohydrate Restriction Azienda Ospedaliero, Universitaria Pisana new
2026-09-03 NCT07801378 Comparing Two Low-Carbohydrate Diets With a Standard Diet in Type 2 Diabetes National Nutrition and Food Technology Institute new
2026-09-03 NCT07802899 An Exploratory Study of Single-Dose and Multiple-Doses IBI3042 in Healthy, Overweight, or… Hongwei Jiang new Phase 1
2026-09-01 NCT07797140 The Effect of Acupuncture on Sarcopenia and Obesity in Patients With Sarcopenic Obesity. Ayşe Ukbe Baykut new
2026-09-01 NCT07796503 TSBL-Based Versus BMI-Based Biliopancreatic Limb Length in One-Anastomosis Gastric Bypass National Scientific Center of Surgery named after A.N.Syzganov new
2026-09-01 NCT07796815 Optimizing GWG in Obese Pregnant Women: A Nationwide Real-World Study Using the U.S… Shanghai First Maternal and Infant Health Hospital affiliated to Tongji University Medical School new
2026-08-31 NCT07794111 A Clinical Trial of TQF6422 Injection in Overweight or Obese Healthy Subjects. Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. new Phase 1
2026-08-27 NCT07789223 Weight and Metabolic Management Study Elenzia new

Active trials by phase

Early Phase 1
25
Phase 1
144
Phase 1/2
32
Phase 2
148
Phase 2/3
12
Phase 3
141
Phase 4
98
Not charted: 1,882 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 2,482

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT06857942 A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation… Eli Lilly and Company Recruiting 2026-09-04
NCT05051436 The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics Philip Kern Recruiting 2026-08-31
NCT07154719 GLP-1R Actions on Muscle and the Skeleton Pennington Biomedical Research Center Recruiting 2026-08-27
NCT07554638 Incretin Therapies in Obesity-related HFpEF Columbia University Recruiting 2026-08-24
NCT07218445 The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in… Mayo Clinic Recruiting 2026-08-18
NCT07275697 Waiting on Atrial Fibrillation Intervention Therapy (WAIT) Study Emma Svennberg Recruiting 2026-08-10
NCT06374875 Fibrosis Lessens After Metabolic Surgery The Cleveland Clinic Recruiting 2026-07-31
NCT07728383 A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity Gila Therapeutics, Inc. Recruiting 2026-07-27
NCT07257484 Tirzepatide's Role in Postmenopausal HR+ Breast Cancer Survivors Weill Medical College of Cornell University Recruiting 2026-07-22
NCT07247084 A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants… Eli Lilly and Company Recruiting 2026-07-07
NCT06396416 Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2 Western University, Canada Recruiting 2026-06-29
NCT06864026 A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in… Eli Lilly and Company Recruiting 2026-06-11
NCT05919797 Weight Loss Study: Genetics and Response to Naltrexone/Bupropion Columbia University Recruiting 2026-06-10
NCT05320796 The Bioavailability and Effect on Pouch pH of Esomeprazole After Gastric Bypass Prof Urs Zingg Recruiting 2026-06-09
NCT05975580 Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain… University of California, Irvine Recruiting 2026-06-09
NCT07588438 Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay. Las Rías Medical Center Recruiting 2026-05-19
NCT06721507 2024 Tirzepatide-Bariatric Surgery Marlene Starr Recruiting 2026-05-14
NCT05305313 Evaluation of Propofol Dosing Based on Total Body Weight Using Closes-loop Anaesthesia… Sir Ganga Ram Hospital Recruiting 2026-04-27
NCT07096908 Tirzepatide Use in People With Obesity and Type 1 Diabetes Dasman Diabetes Institute Recruiting 2026-04-20
NCT07513168 Low-Dose Semaglutide for Weight Loss in Obese Non-Diabetic Pakistani Adults Asian Institute Of Medical Sciences Recruiting 2026-04-06
NCT05744479 Metformin for Antipsychotic-induced Weight Gain in Adults With Intellectual Disability Centre for Addiction and Mental Health Recruiting 2026-03-31
NCT07213466 Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder Mayo Clinic Recruiting 2026-03-11
NCT07401992 Effects of Semaglutide on Clinical Outcomes and Metabolic Inflammation in Psoriasis Hospital Universitario Dr. Jose E. Gonzalez Recruiting 2026-02-11
NCT07163650 Evaluating Anti-Obesity Medications 6 Months After Metabolic Surgery The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Recruiting 2026-01-27
NCT06132477 Impact GLP-1 Agonists Following Bariatric University of Missouri-Columbia Recruiting 2026-01-22
See all 2,482 active Obesity trials with filters →

Top sponsors by active trials in this area

Novo Nordisk A/S (59) · Eli Lilly and Company (50) · University of Colorado, Denver (29) · Mayo Clinic (25) · Norwegian University of Science and Technology (25) · Cairo University (24) · University of Alabama at Birmingham (18) · Massachusetts General Hospital (17) · Pennington Biomedical Research Center (17) · Assistance Publique - Hôpitaux de Paris (15)

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