Sponsor Pipeline

Amgen Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-07-19
87
Active Trials
42
Recruiting
44
Phase 3
10
Disease Areas
25
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-07-17 NCT05882877
A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult…
Trial terminated
2026-07-17 NCT05882877
A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult…
critical why stopped: null → "Sponsor Decision"
2026-07-17 NCT07213674
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With…
Trial sites expanded: 136 -> 140 locations
2026-07-17 NCT07313761
A Trial to Compare the Extent to Which Maridebart Cafraglutide (AMG 133) is Made…
Trial completed
2026-07-17 NCT05920356
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum…
Trial sites expanded: 383 -> 401 locations
2026-07-11 NCT07037433
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in…
Trial sites expanded: 774 -> 781 locations
2026-07-11 NCT06401044
A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
Trial sites expanded: 40 -> 44 locations
2026-07-10 NCT06502977
Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer…
date change Completion pushed: 2027-01-08 -> 2027-09-10
2026-07-08 NCT06248619
A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in…
date change Completion pushed: 2026-09-02 -> 2026-11-13
2026-07-07 NCT07614776
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA®…
Trial sites expanded: 20 -> 27 locations
2026-07-03 NCT07575399
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor…
Trial sites expanded: 40 -> 43 locations
2026-07-03 NCT07037459
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection…
Trial sites expanded: 605 -> 628 locations
2026-07-03 NCT06376045
A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma
Trial completed
2026-07-02 NCT07523711
Effect of Maridebart Cafraglutide on How Oral Contraceptives Are Absorbed and Processed…
date change Primary completion pushed: 2026-10-07 -> 2026-11-18
2026-07-02 NCT07523711
Effect of Maridebart Cafraglutide on How Oral Contraceptives Are Absorbed and Processed…
date change Completion pushed: 2026-10-07 -> 2026-11-18
2026-07-02 NCT07545226
Comparing the Extent to Which Two Evolocumab Drug Products Are Made Available in the Body…
Recruitment opened
2026-07-02 NCT07545226
Comparing the Extent to Which Two Evolocumab Drug Products Are Made Available in the Body…
Trial sites expanded: 0 -> 5 locations
2026-07-01 NCT04994717
Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard…
date change Completion pushed: 2031-05-12 -> 2031-06-30
2026-07-01 NCT03600883
A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib…
Trial completed
2026-06-27 NCT06598306
Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer…
date change Primary completion pushed: 2027-03-03 -> 2027-04-24
Showing 20 of 25 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-07-13 NCT07700238 A Study of Romiplostim Plus Predniso(lo)ne vs. Predniso(lo)ne Alone for the Treatment of… Phase 3 Not Yet Recruiting
2026-07-06 NCT07684144 Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of… Phase 3 Not Yet Recruiting
2026-07-06 NCT07684235 Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of… Phase 3 Not Yet Recruiting
Active Trials by Phase
Phase 4
3
Phase 3
44
Phase 2
10
Phase 1/2
4
Phase 1
24
Not specified
2
Active Trials — top 25 of 87
NCT IDTitleConditionStatus
Phase 4
NCT06072482 A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis Antineutrophil Cytoplasmic Antibody-associated Vasculitis Recruiting
NCT06332014 Evaluation of Efficacy and Safety of Prolia in Subjects of Male Osteoporosis in Mainland… Osteoporosis Active, Not Recruiting
NCT06588153 A Study for the Evaluation of Efficacy and Safety of Prolia® in Participants With… Glucocorticoid-induced Osteoporosis Active, Not Recruiting
Phase 3
NCT03633708 A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and… Secondary Hyperparathyroidism Recruiting
NCT03969329 A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving… Secondary Hyperparathyroidism Recruiting
NCT07293260 Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary… Cardiovascular Disease Recruiting
NCT04804553 Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis Active Juvenile Psoriatic Arthritis Recruiting
NCT06747949 A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) Sjögren's Syndrome Recruiting
NCT07225686 Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea… Obesity Recruiting
NCT07226765 Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea… Obstructive Sleep Apnea Recruiting
NCT06321601 Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing… Vasculitis Recruiting
NCT07366086 Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis… Osteogenesis Imperfecta Recruiting
NCT07037459 Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection… Heart Failure With Preserved Ejection Fraction Recruiting
NCT07575399 Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor… Obesity or Overweight Recruiting
NCT07037433 Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in… Atherosclerotic Cardiovascular Disease Recruiting
NCT07136012 OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a)… Cardiovascular Disease Recruiting
NCT07388498 A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and… Uncontrolled Gout Recruiting
NCT07614776 A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA®… Neovascular Age-related Macular Degeneration Recruiting
NCT05920356 A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum… Non-Small Cell Lung Cancer (NSCLC) Recruiting
NCT06252649 Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without… Metastatic Colorectal Cancer Recruiting
NCT07005128 A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab… Small-cell Lung Cancer Recruiting
NCT07213674 A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With… Metastatic Castration-resistant Prostate Cancer Recruiting
NCT06858878 Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes… Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight Active, Not Recruiting
NCT05740566 Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung… Small Cell Lung Cancer (SCLC) Active, Not Recruiting
NCT06245408 A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)… Sjögren's Syndrome (SS) Active, Not Recruiting
View all 87 active Amgen trials with filters →
Disease Areas
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