Disease landscape

Type 2 Diabetes clinical trials

Get alerts when Type 2 Diabetes trials change

1,020 active trials 508 recruiting 75 Phase 3 641 sponsors 169 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 54 of 169 changes on 20 trials

2026-08-28
Trial terminated
Trial terminated: Funding was terminated for the study.
Enrollment reduced: 353 → 37 participants
Primary completion moved earlier: 2028-03-31 → 2026-05-19
Completion moved earlier: 2028-05-31 → 2026-06-19
NCT05884775 Novel Digital Patient-Reported Outcomes Tool for Diabetes Management · NYU Langone Health
2026-09-03
Primary completion pushed: 2026-08 → 2026-12
Enrollment increased: 78 → 114 participants
Interventions modified
Completion pushed: 2026-08 → 2026-12
Trial arms changed: 11 → 13
NCT07463196 A Study Investigating the Safety, Absorption, Elimination, and the Effect on the Immune… · AC Immune SA · Phase 1
2026-09-04
Primary completion pushed: 2026-12-31 → 2027-05-31
NCT07325838 Digital Self-Management Education and Support for Young Adults With Type 2 Diabetes… · Recep Turan
2026-08-22
Primary completion pushed: 2026-02 → 2026-09
Enrollment closed, study ongoing
Completion pushed: 2026-06 → 2027-01
NCT05822544 Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or… · OrsoBio, Inc · Phase 1
2026-09-05
Primary completion pushed: 2026-07-30 → 2026-10-30
Completion pushed: 2026-07-30 → 2026-10-30
NCT06208189 Is the Degree of Perceived Effort During Resistance Exercise Important for Improvements… · University of New Mexico
2026-09-05
Primary completion pushed: 2026-02-01 → 2027-02-15
Enrollment closed, study ongoing
Completion pushed: 2026-02-01 → 2027-03-01
NCT05741125 Improving Appetite Self-Regulation in African American Adults With Type 2 Diabetes · University of North Carolina, Chapel Hill
2026-09-05
Primary completion pushed: 2027-09 → 2028-03
NCT05911256 A Community Health Worker/Pharmacist Team to Improve Blood Sugars in Diabetes Care Using… · University of Massachusetts, Worcester
2026-09-04
Primary completion pushed: 2026-07-30 → 2026-10-30
NCT06115265 Ketogenic Diet and Diabetes Demonstration Project · University of New Mexico
2026-09-03
Primary completion pushed: 2027-02-28 → 2027-06-30
Recruitment opened
Completion pushed: 2027-02-28 → 2027-06-30
NCT07062406 Enhancing Diabetes Care by Treating Insomnia · Tulane University
2026-09-01
Primary completion pushed: 2025-12 → 2026-12-31
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Trial sites expanded: 0 → 3 locations
Completion pushed: 2026-06 → 2027-06
NCT06920355 Community Pharmacy Produce Prescriptions · Tufts University
2026-08-27
Primary completion pushed: 2025-12-01 → 2027-02-01
Trial status changed: Recruiting → Not Yet Recruiting
Completion pushed: 2026-05-01 → 2027-02-01
NCT07114822 HOPE Intervention for Fitness · University of California, Irvine
2026-08-26
Primary completion pushed: 2025-10 → 2028-12
Completion pushed: 2026-10 → 2029-12
NCT04326192 Brown Adipose Tissue Activation by Spinal Cord Stimulation · Oregon Health and Science University
2026-08-25
Primary completion pushed: 2026-01-15 → 2026-05-15
Trial completed
Completion pushed: 2026-04-15 → 2026-08-19
NCT07256613 Non-surgical Periodontal Therapy and Kidney Outcomes in Type 2 Diabetes Mellitus · Dow University of Health Sciences
2026-08-18
Primary completion pushed: 2026-09-30 → 2026-12-31
Recruitment opened
NCT07344701 "Screening for Change: Early Risk Detection and Integrated Prevention for Diabetes and… · Marche Region Regional Health Agency
2026-08-18
Primary completion pushed: 2026-06 → 2026-12
Enrollment closed, study ongoing
Completion pushed: 2026-06 → 2026-12
NCT07148713 Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine · University of North Carolina, Chapel Hill
2026-08-15
Primary completion pushed: 2027-09-30 → 2028-02-28
NCT07538505 Testing a Diabetes Care Program in Rural and Low-Income Clinics · The University of Texas Medical Branch, Galveston
2026-08-13
Primary completion pushed: 2025-02-28 → 2025-12-01
Enrollment reduced: 720 → 556 participants
Trial completed
Completion pushed: 2025-12-01 → 2025-12-31
NCT06833541 Research on Gut Microbiota and Metabolomics in Diabetic Kidney Disease · The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2026-08-13
Primary completion pushed: 2026-04 → 2028-12
Completion pushed: 2026-04 → 2028-12
NCT06993454 Acute Exercise and Endogenous Glucose Production in Type 2 Diabetes: Implications for… · AdventHealth Translational Research Institute
2026-08-11
Primary completion pushed: 2026-03-31 → 2026-12-31
Completion pushed: 2026-07-01 → 2027-03-31
NCT06830096 Role of KATP Channel Loss in Type 2 Diabetes · Washington University School of Medicine
2026-08-07
Primary completion pushed: 2025-09-01 → 2026-04-01
Enrollment reduced: 50 → 40 participants
Trial status changed: Enrolling by Invitation → Completed
Completion pushed: 2025-10-01 → 2026-08-01
NCT06900946 Evaluation of the Effects of Gluten Free Diet on Clinical Symptoms and Glycemic Index in… · National Nutrition and Food Technology Institute

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-03 NCT07802106 Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow… Universidade Sao Francisco new
2026-09-03 NCT07801131 ULTRASONOGRAPHIC EVALUATION OF TALAR CARTILAGE THICKNESS IN PATIENTS WITH DIABETIC… Istanbul Physical Medicine Rehabilitation Training and Research Hospital new
2026-09-02 NCT07800468 Efficacy of Topical Lidocaine Gel vs. Oral Duloxetine for Painful Diabetic Peripheral… Wah Medical college , POF hospital new Phase 4
2026-08-31 NCT07794384 Effects of a Researcher-Designed Diabetes Self-Management App on Self-Management… Fu Jen Catholic University Hospital new
2026-08-28 NCT07793292 Telehealth Educational Intervention for Adults With Type 2 Diabetes in Oman Sultan Qaboos University new
2026-08-28 NCT07793305 Precision Diabetes Education Guided by Diabetes Complication Risk Assessment Taiwanese Association of Diabetes Educators new
2026-08-26 NCT07787403 Pilot RCT of PIPE-AI for Prediabetes and Diabetes Self-Management The Hong Kong Polytechnic University new
2026-08-25 NCT07786194 Improvement Through Movement - Balance Control and Somatosensory Function in People With… Universiteit Antwerpen new
2026-08-24 NCT07783451 Effectiveness of Combining Patient Follow-Up With an Educational Intervention on… Aysenur Aktemur new
2026-08-21 NCT07778719 Metformin-Dapagliflozin Effects on IGF-1 in Male T2DM With MASLD The 95th Hospital of Putian，Putian, Fujian, China new

Active trials by phase

Early Phase 1
10
Phase 1
37
Phase 1/2
6
Phase 2
54
Phase 2/3
5
Phase 3
70
Phase 4
71
Not charted: 767 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 1,020

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07771010 The Effect of Empagliflozin and Metformin on Oxidative Capacity and Microvascular… University Medical Centre Ljubljana Recruiting 2026-08-18
NCT05305287 Quantifying Hepatic Mitochondrial Fluxes in Humans The University of Texas Health Science Center at San Antonio Recruiting 2026-08-17
NCT07719894 Cilostazol and Aspirin for Cardiovascular Event Prevention in Patients With Type 2… Seoul National University Bundang Hospital Recruiting 2026-07-22
NCT07711171 Efficacy and Safety of Canagliflozin in the Treatment of Type 2 Diabetes With Mild… Fudan University Recruiting 2026-07-17
NCT06003153 GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at… Massachusetts General Hospital Recruiting 2026-07-08
NCT07307235 Efficacy and Safety of iGlarLixi Versus Standard of Care in a Real-world Adult China… Shanghai Zhongshan Hospital Recruiting 2026-07-07
NCT06291155 Mechanism of SGLT2 Inhibition in the Kidney University of Michigan Recruiting 2026-06-11
NCT07614230 SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue… Junjie Yang Recruiting 2026-05-29
NCT07086443 Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy Sequence LifeScience, Inc. Recruiting 2026-05-19
NCT06399835 Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis Seoul National University Bundang Hospital Recruiting 2026-05-05
NCT06402747 Clopidogrel Versus Cilostazol on Vessels Seoul National University Bundang Hospital Recruiting 2026-05-05
NCT06613854 Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in… University Medical Centre Ljubljana Recruiting 2026-04-30
NCT07558863 Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes The First Affiliated Hospital with Nanjing Medical University Recruiting 2026-04-30
NCT06657209 Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide Stanford University Recruiting 2026-04-20
NCT06706284 Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord… Marzieh Salehi Recruiting 2026-04-13
NCT07272343 The Impact of Semaglutide Compared to Energy Restriction on Type 2 Diabetes Second Affiliated Hospital of Nanchang University Recruiting 2026-04-02
NCT06671587 iGlarLixi CGM Study in Chinese T2D Individuals After OADs Sanofi Recruiting 2026-03-17
NCT07442006 Glycemic Variability of Combination Therapies in T2DM JW Pharmaceutical Recruiting 2026-03-02
NCT07159282 A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single… Applied Biologics, LLC Recruiting 2026-02-11
NCT07401992 Effects of Semaglutide on Clinical Outcomes and Metabolic Inflammation in Psoriasis Hospital Universitario Dr. Jose E. Gonzalez Recruiting 2026-02-11
NCT07314684 GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM Federico II University Recruiting 2026-01-02
NCT07244003 Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor… Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. Recruiting 2025-11-24
NCT06972732 A Phase IV Clinical Trial to Compare the Efficacy and Safety of Metformin+Sodium-Glucose… Boryung Pharmaceutical Co., Ltd Recruiting 2025-09-15
NCT06888050 Efficacy and Safety of Henagliflozin Proline and Metformin Hydrochloride Extended-release… Zhejiang Provincial People's Hospital Recruiting 2025-09-12
NCT06782139 Effects of Enavogliflozin on Coronary Microvascular and Cardiac Function in Obesity Korea University Anam Hospital Recruiting 2025-09-02
See all 1,020 active Type 2 Diabetes trials with filters →

Top sponsors by active trials in this area

Steno Diabetes Center Copenhagen (9) · Eli Lilly and Company (8) · The University of Texas Health Science Center at San Antonio (8) · University of Alabama at Birmingham (8) · AstraZeneca (7) · Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. (7) · National Taiwan University Hospital (7) · Novo Nordisk A/S (7) · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School (7) · University of Manitoba (7)

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