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A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes

Name: A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes — clinical trial record (NCT07843485)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: ZUPREME-4

StatusNot Yet Recruiting

PhasePhase 3

SponsorHoffmann-La Roche

Started2026-09-30

View on ClinicalTrials.gov ↗

Roche/Genentech

364 trials monitored

See 34 trials at risk

Diabetes

4,247 trials monitored

See 176 trials at risk

Obesity

3,523 trials monitored

See 133 trials at risk

Type 2 Diabetes

2,082 trials monitored

See 101 trials at risk

This study will evaluate the efficacy and safety of petrelintide compared with placebo, in conjunction with a reduced-calorie diet and increased physical activity, for weight management in participants living with overweight or obesity and with Type 2 Diabetes (T2D).

Trial Details

NCT Number	NCT07843485
Lead Sponsor	Hoffmann-La Roche Collaborators: Zealand Pharma
Conditions	Obesity or Overweight, Type 2 Diabetes
Enrollment	600 participants
Start Date	2026-09-30
Primary Completion	2028-10-20 (estimated)
Study Completion	2029-01-19 (estimated)
Updated on ClinicalTrials.gov	2026-09-28