131 trials changed in the last 30 days: 3 stopped, 60 with notable changes, 68 with minor changes only.
Withdrawn before enrolling
Hôpital Universitaire SahloulNot specified NCT07147699 Registry history of NCT07147699 on ClinicalTrials.gov (opens the registry)
Trial terminated
Also in this update: Study completion date changed from estimate of Jan 2027 to Apr 14, 2026; Final enrollment: 154 participants (planned 710)
University Hospital, MontpellierNot applicable NCT04554277 Registry history of NCT04554277 on ClinicalTrials.gov (opens the registry)
Trial terminated
Also in this update: Primary completion date changed from estimate of Apr 15, 2027 to Sep 7, 2026; Final enrollment: 69 participants (planned 150)
Hackensack Meridian HealthNot applicable NCT06937827 Registry history of NCT06937827 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Jun 2026 to Nov 2027
Bodyport Inc.Not specified NCT07059962 Registry history of NCT07059962 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Jun 2026 to Nov 2027
EBR Systems, Inc.Not applicable NCT02922036 Registry history of NCT02922036 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Dec 31, 2027 to Dec 31, 2028
Also in this update: Enrollment increased: 3000 → 4000 participants; Trial arms changed: 2 → 3
Paragonix TechnologiesNot specified NCT04141605 Registry history of NCT04141605 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Dec 31, 2026 to Jan 1, 2028
Heartfelt TechnologiesNot applicable NCT06222099 Registry history of NCT06222099 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Aug 2026 to Mar 31, 2027
Also in this update: Study completion pushed from Dec 2026 to Jun 2027
University of AlbertaPhase 2 NCT06570473 Registry history of NCT06570473 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Aug 31, 2026 to Aug 31, 2027
Ohio State UniversityNot applicable NCT06081543 Registry history of NCT06081543 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Dec 15, 2023 to Apr 2027
Also in this update: Enrollment reopened; Enrollment increased: 71 → 90 participants
Edwards LifesciencesNot applicable NCT03523416 Registry history of NCT03523416 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Aug 2025 to Dec 2026
Also in this update: Enrollment increased: 5 → 20 participants; Study completion pushed from Dec 2026 to Mar 2027
BiVACOR Inc.Not applicable NCT06174103 Registry history of NCT06174103 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Dec 31, 2026 to Dec 31, 2027
Also in this update: Recruitment opened; Study completion pushed from Jan 15, 2027 to Jan 15, 2028
EchosensNot applicable NCT07222813 Registry history of NCT07222813 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Feb 2026 to Feb 2027
Also in this update: Trial status changed: Enrolling by Invitation → Recruiting
IRCCS Policlinico S. DonatoNot specified NCT07095634 Registry history of NCT07095634 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Mar 2027 to Mar 2028
Oslo University HospitalNot specified NCT05868616 Registry history of NCT05868616 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Sep 2026 to Sep 2027
Also in this update: Study completion pushed from Mar 2027 to Sep 2027
Johns Hopkins UniversityNot applicable NCT06364644 Registry history of NCT06364644 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Aug 19, 2026 to Sep 1, 2030
Icahn School of Medicine at Mount SinaiNot applicable NCT06228209 Registry history of NCT06228209 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Apr 30, 2026 to Oct 31, 2026
Also in this update: Trial status changed: Not Yet Recruiting → Active, Not Recruiting; Study completion pushed from Jul 31, 2026 to Oct 31, 2026
Mansoura UniversityPhase 4 NCT07351864 Registry history of NCT07351864 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from May 2028 to May 2029
Also in this update: Enrollment reduced: 80 → 70 participants; Study completion pushed from Oct 2028 to Oct 2029
Sahlgrenska University HospitalNot applicable NCT07632027 Registry history of NCT07632027 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Dec 31, 2025 to Dec 31, 2026
Also in this update: Primary endpoint(s) modified; Enrollment increased: 90 → 140 participants
French Cardiology SocietyNot applicable NCT03895541 Registry history of NCT03895541 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Jan 1, 2028 to Oct 2, 2028
Also in this update: Study completion pushed from Jan 1, 2030 to Oct 2, 2030
Nantes University HospitalNot applicable NCT06445231 Registry history of NCT06445231 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Tenax Therapeutics, Inc.Phase 3 NCT07288398 Registry history of NCT07288398 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Study completion pushed from Jun 30, 2026 to Oct 31, 2026; Primary completion date changed from estimate of Jun 30, 2026 to Feb 11, 2026
Medtronic Cardiac Rhythm and Heart FailureNot specified NCT06540521 Registry history of NCT06540521 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Innovent Biologics (Suzhou) Co. Ltd.Phase 2 NCT06862908 Registry history of NCT06862908 on ClinicalTrials.gov (opens the registry)
Trial completed
Samara State Medical UniversityPhase 4 NCT05802849 Registry history of NCT05802849 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Feb 2026 to Aug 1, 2026; Final enrollment: 40 participants (planned 34)
Miulli General HospitalNot applicable NCT05491655 Registry history of NCT05491655 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Study completion pushed from Jul 1, 2026 to Dec 1, 2026
Başakşehir Çam & Sakura City HospitalPhase 4 NCT06495892 Registry history of NCT06495892 on ClinicalTrials.gov (opens the registry)
Trial status changed: Enrolling by Invitation → Active, Not Recruiting
Also in this update: Study completion moved earlier from Aug 31, 2028 to Jul 9, 2028; Primary completion moved earlier from Mar 30, 2028 to Jan 9, 2028
Medisch Spectrum TwenteNot applicable NCT06844006 Registry history of NCT06844006 on ClinicalTrials.gov (opens the registry)
Trial status changed: Enrolling by Invitation → Active, Not Recruiting
University Medical Center GroningenPhase 3 NCT05374291 Registry history of NCT05374291 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Mar 31, 2031 to Dec 2, 2024
University of Texas Southwestern Medical CenterNot specified NCT02791880 Registry history of NCT02791880 on ClinicalTrials.gov (opens the registry)
Trial completed
VA Office of Research and DevelopmentNot applicable NCT04506606 Registry history of NCT04506606 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Sep 24, 2026 to Dec 8, 2026
Novartis PharmaceuticalsPhase 1 NCT07465653 Registry history of NCT07465653 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Medical University of WarsawPhase 4 NCT04654988 Registry history of NCT04654988 on ClinicalTrials.gov (opens the registry)
Trial status changed: Unknown → Completed
Medical University InnsbruckNot specified NCT02448485 Registry history of NCT02448485 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Apr 2026 to Oct 2026
Biotronik SE & Co. KGNot applicable NCT06620237 Registry history of NCT06620237 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Dec 2026 to Jun 2027
Also in this update: Study completion pushed from Jul 1, 2028 to Jun 1, 2030
Gradient Denervation TechnologiesNot applicable NCT06052072 Registry history of NCT06052072 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Primary and study completion pushed from Sep 1, 2026 to Nov 1, 2026
Erasmus Medical CenterNot specified NCT06785506 Registry history of NCT06785506 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Nov 30, 2025 to Jun 30, 2025; Final enrollment: 160 participants (planned 120)
Chinese University of Hong KongNot specified NCT05797649 Registry history of NCT05797649 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Primary completion pushed from Aug 2026 to Jan 2027; Study completion pushed from Aug 2026 to Aug 2027
Vanderbilt University Medical CenterNot applicable NCT06479876 Registry history of NCT06479876 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Primary and study completion moved earlier from Oct 2027 to Jul 2027; Final enrollment: 1500 participants (planned 10000)
Tulane UniversityNot specified NCT06753045 Registry history of NCT06753045 on ClinicalTrials.gov (opens the registry)
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Also in this update: Study completion pushed from Dec 30, 2025 to Dec 31, 2026; Primary completion date changed from estimate of Oct 1, 2025 to Dec 1, 2025
Bayburt UniversityNot applicable NCT06838169 Registry history of NCT06838169 on ClinicalTrials.gov (opens the registry)
Completed without a posted recruiting period
Also in this update: Primary completion date changed from estimate of Sep 15, 2025 to Feb 15, 2026
Naile ALANKAYANot applicable NCT07017751 Registry history of NCT07017751 on ClinicalTrials.gov (opens the registry)
Trial status changed: Recruiting → Not Yet Recruiting
Also in this update: Primary completion pushed from Jun 2036 to Dec 2036; Study completion pushed from Jun 2040 to Dec 2040
The Cleveland ClinicNot specified NCT07649148 Registry history of NCT07649148 on ClinicalTrials.gov (opens the registry)
Trial completed
Weill Medical College of Cornell UniversityNot applicable NCT06994325 Registry history of NCT06994325 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Jul 28, 2028 to Jan 1, 2025; Final enrollment: 81 participants (planned 160)
University of EdinburghNot applicable NCT04591639 Registry history of NCT04591639 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of May 2, 2026 to May 2, 2025; Final enrollment: 4 participants (planned 6)
Barts & The London NHS TrustNot applicable NCT05696522 Registry history of NCT05696522 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Final enrollment: 32 participants (planned 64)
University of Alabama at BirminghamNot applicable NCT05879887 Registry history of NCT05879887 on ClinicalTrials.gov (opens the registry)
Trial completed
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y CajalNot specified NCT05992558 Registry history of NCT05992558 on ClinicalTrials.gov (opens the registry)
Trial completed
Brigham and Women's HospitalNot specified NCT07390110 Registry history of NCT07390110 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Dec 30, 2025 to Feb 10, 2026; Final enrollment: 26 participants (planned 30)
University of Illinois at ChicagoNot applicable NCT06473532 Registry history of NCT06473532 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Sep 2026 to Dec 2026
University of OklahomaNot applicable NCT02898181 Registry history of NCT02898181 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 585 → 594 locations
And 1 more change in the last 30 days
Boehringer IngelheimPhase 3 NCT06935370 Registry history of NCT06935370 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 25 → 28 locations
Edgewise Therapeutics, Inc.Phase 2 NCT07795814 Registry history of NCT07795814 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 9 → 25 locations
Foundry Innovation & Research 1, Limited (FIRE1)Not applicable NCT07574593 Registry history of NCT07574593 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Aug 2031 to Oct 2031
Wake Forest University Health SciencesNot applicable NCT07400042 Registry history of NCT07400042 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Dec 31, 2026 to Apr 4, 2027
University Hospital, Basel, SwitzerlandNot specified NCT04000061 Registry history of NCT04000061 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 653 → 664 locations
And 1 more change in the last 30 days
Boehringer IngelheimPhase 3 NCT06424288 Registry history of NCT06424288 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 672 → 679 locations
AstraZenecaPhase 3 NCT07761117 Registry history of NCT07761117 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 205 → 208 locations
CytokineticsPhase 3 NCT06736574 Registry history of NCT06736574 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 1 → 17 locations
Also in this update: Study completion moved earlier from Jul 3, 2028 to Apr 30, 2028
BayerNot specified NCT07235462 Registry history of NCT07235462 on ClinicalTrials.gov (opens the registry)
Enrollment increased: 60 → 70 participants
And 1 more change in the last 30 days
University Medical Centre LjubljanaPhase 4 NCT07405944 Registry history of NCT07405944 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 43 → 46 locations
Sunnybrook Health Sciences CentreNot applicable NCT05427370 Registry history of NCT05427370 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 13 → 16 locations
And 1 more change in the last 30 days
Pulnovo Medical, Inc.Not applicable NCT07214376 Registry history of NCT07214376 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 20 → 26 locations
Axon Therapies, Inc.Not applicable NCT04592445 Registry history of NCT04592445 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 16 → 21 locations
VA Office of Research and DevelopmentNot applicable NCT05996328 Registry history of NCT05996328 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Jul 1, 2026 to Jul 1, 2027
University of PennsylvaniaNot applicable NCT05736484 Registry history of NCT05736484 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Aug 31, 2026 to Feb 28, 2027
Vanderbilt University Medical CenterPhase 2 NCT04481919 Registry history of NCT04481919 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Jun 30, 2026 to Mar 8, 2027
Also in this update: Primary completion date changed from estimate of Jan 31, 2026 to Sep 4, 2025
Baystate Medical CenterNot applicable NCT07123480 Registry history of NCT07123480 on ClinicalTrials.gov (opens the registry)
Registry marked status Unknown (sponsor has not verified the record since Dec 2023); last known: Not Yet Recruiting
Power Life Sciences Inc.Not specified NCT05516290 Registry history of NCT05516290 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Mar 2024); last known: Enrolling by Invitation
Nihon KohdenNot specified NCT05441696 Registry history of NCT05441696 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Feb 2023); last known: Active, Not Recruiting
Corvia MedicalNot applicable NCT03088033 Registry history of NCT03088033 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Hospital Clinic of BarcelonaPhase 3 NCT06619600 Registry history of NCT06619600 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
University of LeedsPhase 2/3 NCT04201015 Registry history of NCT04201015 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting
Dongying ZhangPhase 4 NCT06604611 Registry history of NCT06604611 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Katarzyna PiotrowiczNot applicable NCT06647212 Registry history of NCT06647212 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting
Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityNot applicable NCT06633107 Registry history of NCT06633107 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting
Hagar Mahmoud HammadNot specified NCT06621862 Registry history of NCT06621862 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
The University of Hong Kong-Shenzhen HospitalNot specified NCT06593223 Registry history of NCT06593223 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting
Shanghai Zhongshan HospitalNot specified NCT06591923 Registry history of NCT06591923 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Brigham and Women's HospitalNot specified NCT06588452 Registry history of NCT06588452 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Universitas DiponegoroNot specified NCT06586008 Registry history of NCT06586008 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Kafrelsheikh UniversityNot specified NCT06585761 Registry history of NCT06585761 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
University of Maryland, BaltimoreNot applicable NCT06350695 Registry history of NCT06350695 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
University of Castilla-La ManchaNot applicable NCT06211361 Registry history of NCT06211361 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Feb 2024); last known: Recruiting
NHS Greater Glasgow and ClydeNot specified NCT06101693 Registry history of NCT06101693 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Imperial College LondonNot applicable NCT06091475 Registry history of NCT06091475 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Closed Joint-Stock Company NeoCorNot specified NCT05998694 Registry history of NCT05998694 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
Fundación Pública Andaluza para la gestión de la Investigación en SevillaNot specified NCT05176548 Registry history of NCT05176548 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Wonju Severance Christian HospitalNot specified NCT04437628 Registry history of NCT04437628 on ClinicalTrials.gov (opens the registry)
Changed
Registry verification sweep
Changed
| First posted | Trial | Sponsor | Phase |
|---|---|---|---|
| 2026-10-16 | NCT07877831 Vericiguat Use and Incident Atrial Fibrillation in Chronic Heart Failure | Beijing Tsinghua Chang Gung Hospital new | |
| 2026-10-13 | NCT07870369 Cardiovascular Risk in Patients With Primary Hyperparathyroidism | Medical University of Sofia new | |
| 2026-10-07 | NCT07864363 Rhythmic Auditory Stimulation in Heart Failure Patients | Necmettin Erbakan University new | |
| 2026-10-02 | NCT07855692 The Clinical Trial of Tamibarotene for Patients With HFpEF (RELIEF Trial) | Nagoya University new | Phase 2 |
| 2026-09-30 | NCT07849361 Feasibility Study on the Implementation of a Program to Facilitate the Return Home of… | Sant'Innovation new | |
| 2026-09-30 | NCT07848529 Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study | Baim Institute for Clinical Research new | |
| 2026-09-29 | NCT07847983 Heart Failure in Women: Epidemiological and Prognostic Insights | Carolina Ortiz Cortes new | |
| 2026-09-25 | NCT07842874 A Comparison of Left Bundle Branch Optimized Cardiac Resynchronization Therapy vs Left… | PD Dr. Guram Imnadze new | |
| 2026-09-21 | NCT07830758 Resmetirom in Patients With MASH and HFpEF | Madrigal Pharmaceuticals, Inc. new | Phase 1 |
| 2026-09-17 | NCT07823998 Coffee Use, Physical Activity and Symptomatic Ventricular Arrhythmias in Patients With… | Jean-Benoît Le Polain de Waroux new |
| Early Phase 1 | 10 | |
| Phase 1 | 34 | |
| Phase 1/2 | 24 | |
| Phase 2 | 71 | |
| Phase 2/3 | 13 | |
| Phase 3 | 70 | |
| Phase 4 | 81 |
Mayo Clinic (18) · Yale University (13) · Assiut University (11) · National Taiwan University Hospital (11) · University of Texas Southwestern Medical Center (11) · Assistance Publique - Hôpitaux de Paris (10) · The Cleveland Clinic (10) · University Medical Center Groningen (10) · Duke University (9) · Massachusetts General Hospital (9)