Sponsor pipeline

Yale University clinical trial pipeline

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366 active trials 232 recruiting 11 Phase 3 55 disease areas 79 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days showing 45 of 79 changes on 20 trials

2026-09-15
Recruitment suspended
Recruitment suspended: PI in transition, assessing feasibility of study continuation
Primary completion pushed: 2026-06 → 2026-12
Completion pushed: 2026-06 → 2026-12
NCT05495984 Neuroplasticity in Maternal Opioid Use Disorder (OUD)
2026-10-02
Primary completion pushed: 2027-10 → 2029-05-31
Completion pushed: 2027-10 → 2029-05-31
NCT07201402 Long Term Evaluation of Scapular-inserted Contraceptive Implants · Phase 2
2026-09-30
Primary completion pushed: 2026-09-01 → 2027-09-01
Completion pushed: 2026-09-01 → 2027-09-01
NCT07103902 Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms
2026-09-29
Primary completion pushed: 2026-07-30 → 2027-07-15
Completion pushed: 2026-07-30 → 2027-07-15
NCT05756257 Blood Pressure Variability and Ischemic Stroke Outcome
2026-09-26
Primary completion pushed: 2026-06 → 2027-08
Completion pushed: 2026-06 → 2027-08
NCT06513819 HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot… · Phase 1
2026-09-23
Primary completion pushed: 2026-06-30 → 2027-09
Completion pushed: 2026-12-31 → 2027-09
NCT04131829 Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD · Phase 1/2
2026-09-24
Primary completion pushed: 2026-12 → 2027-12
Completion pushed: 2026-12 → 2027-12
NCT05909085 The Impact of Needle Manipulation and Accuracy Between Hand Held Automatic and…
2026-09-22
Primary completion pushed: 2026-02 → 2026-12
Completion pushed: 2026-02 → 2026-12
NCT05784805 Acute Effects of Focused Ultrasound Modulation on EEG Behavior in Status Epilepticus…
2026-09-22
Primary completion pushed: 2026-10 → 2027-02
Completion pushed: 2026-10 → 2027-02
NCT07793383 Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for…
2026-09-11
Primary completion pushed: 2026-10-31 → 2027-02
Enrollment closed, study ongoing
Final enrollment: 4 participants (planned 10)
Completion pushed: 2026-10-31 → 2027-02
NCT07223983 Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery… · Phase 1
2026-09-05
Primary completion pushed: 2026-03-22 → 2026-09-22
Trial status changed: Enrolling by Invitation → Active, Not Recruiting
Completion pushed: 2026-03-22 → 2026-09-22
NCT06940687 Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their…
2026-09-05
Primary completion pushed: 2026-04-10 → 2028-08
Trial status changed: Enrolling by Invitation → Active, Not Recruiting
Completion moved earlier: 2029-04-30 → 2028-08
NCT04599192 Fractional Flow Reserve and Instantaneous Free-wave Ratio Revascularization Strategies in…
2026-09-15
Primary endpoint(s) modified
NCT05726032 Empagliflozin in Patients With Cirrhosis and Ascites · Phase 2
2026-09-15
Primary endpoint(s) modified
NCT06323824 Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid… · Phase 4
2026-09-09
Phase changed: Phase 1/2 → Phase 2
Interventions modified
NCT07796074 Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 2 · Phase 2
2026-09-05
Phase changed: not applicable → Phase 2
NCT06684613 Integrating PrEP Decision Making Into Counseling in Sexual and Reproductive Health Clinics · Phase 2
2026-09-22
Phase changed: not applicable → not specified
Completed without a posted recruiting period
Primary completion confirmed: May 2023 (last estimated July 2027)
Trial arms changed: 2 → 1
NCT04910984 Developing a Chatbot to Promote HIV Testing
2026-10-01
Trial completed
Primary completion confirmed: January 2026 (last estimated June 2026)
NCT04793685 Prazosin for Alcohol Use Disorder With Withdrawal Symptoms · Phase 2
2026-09-30
Trial completed
Final enrollment: 47 participants (planned 80)
Primary completion confirmed: November 2025 (last estimated May 2026)
NCT06963476 rTMS as Add on Treatment for Substance Use Disorders
2026-09-30
Recruitment opened
NCT07488780 Language Network Prehab Via fMRI Neurofeedback

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-23 NCT07835555 Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder… Phase 4 Not Yet Recruiting
2026-09-09 NCT07810764 Facial Vascularized Composite Allotransplantation: A Study Evaluating Safety, Functional… Not Yet Recruiting
2026-09-09 NCT07810790 Upper Extremity Vascularized Composite Allotransplantation: A Study Evaluating Safety… Not Yet Recruiting
2026-09-02 NCT07800520 Characterization of CB1 Receptors Using [11-C]OMAR in Opioid Use Disorder Phase 1 Not Yet Recruiting

Active trials by phase

Early Phase 1
17
Phase 1
40
Phase 1/2
7
Phase 2
63
Phase 2/3
1
Phase 3
10
Phase 4
11
Not charted: 217 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 366

NCT IDTitleConditionStatusUpdated
Phase 4
NCT06323824 Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid… Opioid Use Disorder Recruiting 2026-09-14
NCT05612594 Adipose Dysfunction, Imaging, Physiology, and Outcomes With Sodium Glucose Cotransporter… Sleep Apnea Recruiting 2026-08-27
NCT06334315 Oral Contraceptive Pill (OCP) Pharmacogenomics Contraception Recruiting 2026-07-16
NCT05547048 Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice… HIV Recruiting 2026-06-03
NCT05786417 LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple… Angina Recruiting 2026-04-07
NCT06967519 OPTImizing Malaria And HIV Treatment in a Shifting Landscape in Africa Malaria Recruiting 2026-02-04
NCT07835555 Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder… Tobacco Use Disorder/Cigarette Smoking Not Yet Recruiting 2026-09-23
NCT05671991 Effect of Empagliflozin on Peritoneal and Kidney Function in End Stage Renal Disease End Stage Renal Disease on Dialysis Active, Not Recruiting 2026-09-14
NCT07281014 Unmitigated Aldosterone Signaling During Standard Clinical MRA Dosing Heart Failure Active, Not Recruiting 2026-08-26
NCT05079841 The Stimulation To Induce Mothers Study Oxytocin Active, Not Recruiting 2026-08-17
NCT07176351 Acceptability and Feasibility of Extended-Release Subcutaneous Buprenorphine on a Mobile… Opioid Use Disorder Not Yet Recruiting 2026-07-31
Phase 3
NCT06713616 PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study Depression Recruiting 2026-09-08
NCT05827159 Emergency Department-Initiated Medications for Alcohol Use Disorder Alcohol Use Disorder Recruiting 2026-07-21
NCT07332442 Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive… Sleep Apnea Recruiting 2026-06-03
NCT06494904 Standard Versus High Dose ED-Initiated Buprenorphine Induction Opioid Use Disorder Recruiting 2026-05-28
NCT03907046 Anticoagulation in ICH Survivors for Stroke Prevention and Recovery Intracerebral Hemorrhage Recruiting 2026-05-08
NCT05766592 Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and… Mental Health Issue Recruiting 2026-01-13
NCT05364008 FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A… Leiomyoma, Uterine Active, Not Recruiting 2026-08-20
NCT07281027 COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" New Onset Refractory Status Epilepticus Not Yet Recruiting 2026-08-19
NCT07661342 DEPART Study at Yale Dupuytren's Contracture Not Yet Recruiting 2026-06-22
NCT06375811 Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp Infertility Active, Not Recruiting 2026-06-05
Phase 2/3
NCT04924322 Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies Deep Venous Thrombosis Recruiting 2026-06-08
Phase 2
NCT07201402 Long Term Evaluation of Scapular-inserted Contraceptive Implants Contraception Recruiting 2026-10-01
NCT07610369 The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease Depression Recruiting 2026-09-28
NCT06923527 Circulating Tumor DNA ER+ Breast Cancer Recruiting 2026-09-21
See all 366 active Yale University trials with filters →

Disease areas by active trials, top 10 of 55

Diabetes (15) · Depression (14) · Heart Failure (13) · PTSD (10) · Breast Cancer (8) · Obesity (8) · Type 1 Diabetes (8) · Stroke (7) · Type 2 Diabetes (7) · Epilepsy (5)

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