ClinicalTrials.gov term: Depressive Disorder

Disease landscape

Depression clinical trials

Get alerts when Depression trials change
Data updated daily from ClinicalTrials.gov, last refresh 2026-10-20

What changed in the last 30 days

161 trials changed in the last 30 days: 3 stopped, 70 with notable changes, 88 with minor changes only.

  1. Notable

    Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)

    Primary completion pushed from Sep 30, 2029 to Sep 30, 2030

    Also in this update: Trial status changed: Enrolling by Invitation → Recruiting; Study completion pushed from Oct 14, 2029 to Oct 14, 2030; and 1 more change in the last 30 days

    National Institute on Deafness and Other Communication Disorders (NIDCD)Not specified NCT07149428 Registry history of NCT07149428 on ClinicalTrials.gov (opens the registry)

Show 88 trials with minor changes only
  1. Minor

    MOOD · Mobile Screening for Major Depressive Disorder in Adults From an Ethnically and Socioeconomically Diverse Population

    Trial status changed: Enrolling by Invitation → Active, Not Recruiting

    Also in this update: Primary completion pushed from Oct 2027 to Mar 2028; Study completion moved earlier from Oct 2028 to Mar 2028

    Erasmus Medical CenterNot applicable NCT05989412 Registry history of NCT05989412 on ClinicalTrials.gov (opens the registry)

  2. Minor
    22 trials marked Unknown by the registry's verification sweep

    Registry verification sweep

    Changed

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-10-19 NCT07880171 Intensive Home-based Transcranial Direct Current Stimulation for Long COVID Hospital de Basurto new
2026-10-19 NCT07880457 Improving Perinatal Mental Health Through a Collaborative, Community Health Worker and… American University new
2026-10-19 NCT07879924 Dual Neuromodulation for Depression: Boosting TMS With tES Mersey Care NHS Trust new
2026-10-16 NCT07878754 Remote Medical Monitoring of Patients With Depression ThIA Santé Mentale new Phase 1
2026-10-15 NCT07874685 Mindfulness-Integrated Neuropsychotherapy for Traumatic Brain Injury: A Mixed-Methods… University of Madras new
2026-10-15 NCT07876908 SAINT® Therapy for Memory Problems in Older Adults With Treatment-Resistant Depression BrainHealth Solutions, Inc. new
2026-10-14 NCT07873060 Comparing 10 Hz rTMS and iTBS for Adolescent Depression Qilu Hospital of Shandong University new
2026-10-14 NCT07873905 Digital Single-Session Cognitive Behavioural Therapy in Healthy Adults Brunel University new
2026-10-08 NCT07865728 Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents Universidad Pública de Navarra new
2026-10-08 NCT07866053 AI-Enabled Wearable Monitoring for Detection of Postpartum Depression and Anxiety University of Hawaii new

Active trials by phase

Early Phase 1
18
Phase 1
41
Phase 1/2
28
Phase 2
151
Phase 2/3
17
Phase 3
76
Phase 4
79
Not charted: 1,816 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Top sponsors by active trials in this area

Get alerts when Depression trials change
Status changes, date slips, and new sponsor entrants: detected daily, delivered to your inbox.
Start monitoring free

Narrower conditions

Active trials