Disease landscape

Postpartum Depression clinical trials

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126 active trials 64 recruiting 108 sponsors 15 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days

2026-08-15
notable
Primary completion pushed: 2026-07-31 → 2026-12-31
Completion pushed: 2026-07-31 → 2026-12-31
NCT05763537 Understanding the Role of Doulas in Supporting People With PMADs · University of Montana
2026-09-04
notable
Trial completed
Study completion confirmed: August 2026 (last estimated November 2026)
NCT06877104 Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression · University of Pennsylvania
2026-08-22
notable
Enrollment closed, study ongoing
NCT06877104 Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression · University of Pennsylvania
2026-08-20
notable
Trial completed
Primary completion moved earlier: 2025-09 → 2025-06-14
Completion moved earlier: 2025-09 → 2025-06-14
NCT06365645 Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum… · Women and Infants Hospital of Rhode Island
2026-08-15
notable
Trial completed
NCT05753176 Online 1-Day CBT-Based Workshops for Preventing Postpartum Depression · McMaster University
2026-08-11
notable
Enrollment closed, study ongoing
Primary completion pushed: 2026-11 → 2027-01
NCT05873569 Preventing Postpartum Depression in Immigrant Latinas · Northwestern University
2026-08-07
notable
Recruitment opened
NCT07607613 Parents and Babies Pilot · Northwestern University
2026-08-13
notable
Primary completion pushed: 2027-06 → 2027-08
Completion pushed: 2027-12 → 2028-01
NCT07460063 Routine vs. Early Postpartum Depression Screening: A Pragmatic Clinical Trial · Massachusetts General Hospital
2026-08-07
minor
Completion pushed: 2026-12-31 → 2027-12-31
NCT03167905 CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery) · KK Women's and Children's Hospital · Phase 2/3

Active trials by phase

Early Phase 1
1
Phase 1
1
Phase 1/2
1
Phase 2/3
2
Phase 3
2
Phase 4
3
Not charted: 116 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 126

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT06833788 Treatment of Anaemia After Caesarean With Intravenous Versus Oral Iron and Postpartum… Assistance Publique - Hôpitaux de Paris Recruiting 2026-06-23
NCT07639099 Intranasal Esketamine-dexmedetomidine Combination and Postpartum Depression Peking University First Hospital Not Yet Recruiting 2026-06-15
NCT05698394 Effect of Low-dose Esketamine on Maternal Depression at 3 Years After Childbirth Peking University First Hospital Active, Not Recruiting 2024-12-05
Phase 3
NCT07721961 A Study of MI078 for Postpartum Depression Nanjing Minova Pharmaceutical Co., Ltd. Recruiting 2026-07-23
NCT05186272 mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of… Kaiser Permanente Active, Not Recruiting 2025-08-05
Phase 2/3
NCT03167905 CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery) KK Women's and Children's Hospital Active, Not Recruiting 2026-08-06
NCT05552053 Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women Cedars-Sinai Medical Center Active, Not Recruiting 2026-04-09
Phase 1/2
NCT04685148 Maternal Mental Health Trial Vibe G Frøkjær, MD, PhD Recruiting 2021-09-23
Phase 1
NCT04950868 The Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression Verinder Sharma Active, Not Recruiting 2025-03-05
Early Phase 1
NCT06546358 Quetiapine Versus Trazadone in Women With Postpartum Depression London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Not Yet Recruiting 2024-08-09
Not applicable
NCT05585164 Engage & Connect: A Psychotherapy for Postpartum Depression Weill Medical College of Cornell University Recruiting 2026-08-20
NCT05763537 Understanding the Role of Doulas in Supporting People With PMADs University of Montana Recruiting 2026-08-14
NCT07766161 Informing Implementation of a Circadian-Focused Intervention for Postpartum Depression University of Michigan Recruiting 2026-08-14
NCT05097586 RCT of At-Home tDCS for Depression in Pregnancy Women's College Hospital Recruiting 2026-08-10
NCT07607613 Parents and Babies Pilot Northwestern University Recruiting 2026-08-06
NCT06818734 Implementation of a Clinical Decision Support Tool for Postpartum Depression Weill Medical College of Cornell University Recruiting 2026-07-30
NCT07594743 Feasibility and Acceptability of a Novel Digital Intervention to Prevent Paternal… Women and Infants Hospital of Rhode Island Recruiting 2026-07-13
NCT06445933 Vitamin B6 and Depression in Pregnant and Peri-partum Women National Taiwan University Hospital Recruiting 2026-07-07
NCT06996067 Essential Coaching Postpartum: Evaluating a Parent-focused Postpartum Text Message… IWK Health Centre Recruiting 2026-07-06
NCT06545760 Admission to Kangaroo Mother Care (KMC) Ward and Maternal Postpartum Depression University of Alabama at Birmingham Recruiting 2026-06-22
NCT07214597 NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE) Vanderbilt University Medical Center Recruiting 2026-06-17
NCT03417960 Accelerated iTBS for Post Partum Depression Medical University of South Carolina Recruiting 2026-05-22
NCT05700760 The ROSE Scale-up Study: Informing a Decision About ROSE as Universal PPD Prevention Michigan State University Recruiting 2026-05-18
NCT06277661 The Mom and Infant Outcomes (MOMI) Study Ohio State University Recruiting 2026-05-14
NCT07210255 SAINT in Postpartum Depression (PPD) Magnus Medical Recruiting 2026-05-14

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