Medical University of South Carolina clinical trial pipeline

26 trials changed in the last 30 days: 2 stopped, 15 with notable changes, 9 with minor changes only.

1. Stopped

   Transcranial Magnetic Stimulation for Chronic Scrotal Content Pain

   Withdrawn before enrolling

   Sponsor's reason: Study discontinued before starting

   Also in this update: Primary completion date changed from estimate of Apr 1, 2030 to Sep 23, 2026; Start date changed from estimate of Sep 30, 2026 to Sep 23, 2026

   Medical University of South Carolina·Phase 1/2· NCT07035119· Registry history of NCT07035119 on ClinicalTrials.gov (opens the registry)

   Updated Oct 6, 2026

2. Stopped

   Post-Operative Steroids After Sleep Surgery

   Withdrawn before enrolling

   Sponsor's reason: Lack of funding

   Also in this update: Primary completion date changed from estimate of Jun 30, 2027 to Jul 1, 2026

   Medical University of South Carolina·Phase 2· NCT06818981· Registry history of NCT06818981 on ClinicalTrials.gov (opens the registry)

   Updated Oct 6, 2026

3. Notable

   Brain Metastases in Greater Size - Hypofractionated Options Trial…Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)

   Primary completion pushed from Feb 3, 2029 to Jan 11, 2031

   Also in this update: Completion pushed from Feb 3, 2030 to Jan 11, 2032

   Medical University of South Carolina·Phase 2· NCT07227610· Registry history of NCT07227610 on ClinicalTrials.gov (opens the registry)

   Updated Sep 18, 2026

4. Notable

   Omission of Postoperative Radiation in HPV-Associated…Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)

   Primary completion pushed from Jul 1, 2029 to Oct 31, 2031

   Also in this update: Completion pushed from Jul 1, 2030 to Jul 1, 2034

   Medical University of South Carolina·Phase 2· NCT07513389· Registry history of NCT07513389 on ClinicalTrials.gov (opens the registry)

   Updated Sep 14, 2026

5. Notable

   CBD for Breast Cancer Primary Tumors

   Primary completion pushed from Mar 25, 2028 to Aug 28, 2030

   Also in this update: Completion pushed from Mar 25, 2029 to Aug 28, 2031

   Medical University of South Carolina·Phase 1· NCT06148038· Registry history of NCT06148038 on ClinicalTrials.gov (opens the registry)

   Updated Sep 28, 2026

6. Notable

   Trauma Center-Based Intervention for Adolescent Traumatic Injury…Trauma Center-Based Intervention for Adolescent Traumatic Injury Survivors

   Primary completion pushed from Aug 1, 2026 to Aug 30, 2027

   Also in this update: Enrollment closed, study ongoing

   Medical University of South Carolina·Not applicable· NCT05086757· Registry history of NCT05086757 on ClinicalTrials.gov (opens the registry)

   Updated Sep 23, 2026

7. Notable

   TENS · Transcutaneous Electrical Nerve Stimulation for Pain…TENS · Transcutaneous Electrical Nerve Stimulation for Pain Mitigation During Intrauterine Device Placement

   Primary completion pushed from Aug 2026 to Aug 2027

   Also in this update: Completion pushed from Nov 2026 to Nov 2027

   Medical University of South Carolina·Not applicable· NCT06991075· Registry history of NCT06991075 on ClinicalTrials.gov (opens the registry)

   Updated Sep 18, 2026

8. Notable

   SYNC · Closed-loop rTMS-EEG During Visuomotor Integration

   Primary completion pushed from Aug 31, 2026 to Feb 28, 2027

   Also in this update: Completion moved earlier from Aug 31, 2027 to Feb 28, 2027

   Medical University of South Carolina·Not applicable· NCT07249801· Registry history of NCT07249801 on ClinicalTrials.gov (opens the registry)

   Updated Sep 15, 2026

9. Notable

   Direct vs. Conventional SLT in Open-Angle Glaucoma: A RCT

   Primary completion pushed from Aug 31, 2026 to Oct 31, 2027

   Also in this update: Completion pushed from Aug 31, 2026 to Nov 30, 2027

   Medical University of South Carolina·Not applicable· NCT06925477· Registry history of NCT06925477 on ClinicalTrials.gov (opens the registry)

   Updated Sep 14, 2026

10. Notable

    Written Exposure Therapy Delivered to Adolescents

    Primary endpoint(s) modified

    Medical University of South Carolina·Not applicable· NCT07498257· Registry history of NCT07498257 on ClinicalTrials.gov (opens the registry)

    Updated Sep 15, 2026

11. Notable

    TNM-DGp · Thoracic Neuromodulation for Diabetic Gastroparesis

    Primary endpoint(s) modified

    Also in this update: Phase changed: Phase 1 → not applicable; Results posted: Sep 14, 2026

    Medical University of South Carolina·Not applicable· NCT05273788· Registry history of NCT05273788 on ClinicalTrials.gov (opens the registry)

    Updated Sep 14, 2026

12. Notable

    Endocannabinoids in Reward

    Recruitment opened

    Also in this update: Start date changed from estimate of Sep 15, 2026 to Oct 1, 2026

    Medical University of South Carolina·Phase 2· NCT07815691· Registry history of NCT07815691 on ClinicalTrials.gov (opens the registry)

    Updated Oct 5, 2026

13. Notable

    LiveWell: An Adapted Dialectical Behavioral Therapy Skills…LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Protocol · Metastatic Lung Cancer

    Recruitment opened

    Also in this update: Primary completion pushed from Jun 1, 2027 to Oct 1, 2027

    Medical University of South Carolina·Not applicable· NCT07177846· Registry history of NCT07177846 on ClinicalTrials.gov (opens the registry)

    Updated Oct 7, 2026

14. Notable

    O-tFUS · Olfactory Transcranial Focused Ultrasound

    Recruitment opened

    Medical University of South Carolina·Not applicable· NCT07658365· Registry history of NCT07658365 on ClinicalTrials.gov (opens the registry)

    Updated Oct 6, 2026

15. Notable

    RESP-FIT · Respiratory Muscle Strength Training Intervention for…RESP-FIT · Respiratory Muscle Strength Training Intervention for COPD

    Start date pushed from Sep 15, 2026 to Oct 15, 2026

    Medical University of South Carolina·Not applicable· NCT07811219· Registry history of NCT07811219 on ClinicalTrials.gov (opens the registry)

    Updated Oct 8, 2026

16. Notable

    Resistance Training and Creatine Supplementation for Head and Neck…Resistance Training and Creatine Supplementation for Head and Neck Cancer

    Start date pushed from Sep 15, 2026 to Nov 15, 2026

    Medical University of South Carolina·Not applicable· NCT07838090· Registry history of NCT07838090 on ClinicalTrials.gov (opens the registry)

    Updated Oct 6, 2026

17. Notable

    TRRP+ · CHW-Enhanced Trauma Recovery

    Start date pushed from Sep 1, 2026 to Jan 1, 2027

    Medical University of South Carolina·Not applicable· NCT07818161· Registry history of NCT07818161 on ClinicalTrials.gov (opens the registry)

    Updated Oct 1, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.