Disease landscape

Parkinson's Disease clinical trials

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1,102 active trials 641 recruiting 24 Phase 3 591 sponsors 117 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 44 of 117 changes on 20 trials

2026-08-20
Withdrawn before enrolling
Trial withdrawn: Has yet to begin and may not so halting to avoid participant outreach
Enrollment reduced: 32 → 0 participants
NCT05931484 Study to Evaluate the Safety, Tolerability, Efficacy, and PK of FHL-301 in Parkinson's… · Forest Hills Lab · Phase 2
2026-08-29
Recruitment suspended
Recruitment suspended: Enrollment goals of subjects with Parkinson's disease have been met, and the study has had difficulty enrolling co...
NCT06975059 Novel Shoe Device NUSHU to Measure Gait Analysis in Parkinson's Patients · Weill Medical College of Cornell University
2026-09-02
Primary completion pushed: 2029-05-05 → 2030-07-23
Trial sites expanded: 4 → 16 locations
Completion pushed: 2029-05-05 → 2030-07-23
Trial arms changed: 2 → 4
NCT06565195 A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's… · Prevail Therapeutics · Phase 1
2026-09-04
Primary completion pushed: 2026-07 → 2027-09
Completion pushed: 2026-07 → 2027-09
NCT06234995 Cortical Electrophysiology of Response Inhibition in Parkinson's Disease · Emory University · Phase 4
2026-08-22
Primary completion pushed: 2025-10 → 2027-02
Completion pushed: 2025-10 → 2027-02
NCT06466525 A Two-Part Single and Multiple Ascending Dose Trial of the Safety, Tolerability… · Longevity Biotech Australia Pty Ltd (subsidiary) · Phase 1
2026-09-04
Primary completion pushed: 2025-03 → 2027-01
Completion pushed: 2025-03 → 2027-01
NCT01989013 Effect on Parkinson's Disease After Therapeutic Induction of CranioSacral Integrated… · Zia, Al Raza
2026-08-20
Primary completion pushed: 2026-03-30 → 2026-11-30
Completion pushed: 2026-03-30 → 2026-11-30
NCT07175922 Research Into the Expression of the csgA-gene and How it Changes in Patients With… · Vertero Therapeutics
2026-09-01
Primary completion pushed: 2026-12-31 → 2028-12-31
Completion pushed: 2028-02-28 → 2030-05-28
NCT06683378 A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous… · Craig van Horne, MD, PhD · Phase 1
2026-09-03
Primary completion pushed: 2028-09-01 → 2029-04-01
Completion pushed: 2028-10 → 2029-10
NCT07074119 Sensor-Based Optimization of Therapy for Parkinson's Disease Patients With Motor… · Assistance Publique - Hôpitaux de Paris
2026-09-03
Primary completion pushed: 2025-12-30 → 2026-12-30
Enrollment closed, study ongoing
Completion pushed: 2025-12-30 → 2026-12-30
NCT04426786 Exercise & Brain Energetics in PD · Pacific Parkinson's Research Centre
2026-09-02
Primary completion pushed: 2026-09-30 → 2027-03-31
Completion pushed: 2026-12-31 → 2027-12-31
NCT06993571 Cerebellar Transcranial Alternating Current Stimulation (tACS) to Modulate Parkinson's… · Universitätsklinikum Hamburg-Eppendorf
2026-08-20
Primary completion pushed: 2026-10-24 → 2027-10-24
Completion pushed: 2027-08-24 → 2028-08-24
NCT04373317 Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis · VA Office of Research and Development · Phase 4
2026-08-25
Primary completion pushed: 2026-05-31 → 2026-10-31
Completion pushed: 2026-05-31 → 2026-10-31
NCT04664634 A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's · Northwestern University · Phase 3
2026-08-26
Primary completion pushed: 2026-06-01 → 2026-10-01
NCT06592014 Lithium for Parkinson's: an Extension Trial · State University of New York at Buffalo · Phase 1/2
2026-08-29
Primary completion pushed: 2026-04 → 2027-04
Enrollment closed, study ongoing
Completion pushed: 2026-04 → 2027-04
NCT06846658 Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early… · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
2026-08-29
Primary completion pushed: 2026-07-01 → 2026-12-31
Completion pushed: 2026-12-31 → 2027-03-31
NCT07110376 Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in… · The Cleveland Clinic
2026-08-21
Primary completion pushed: 2028-06-30 → 2032-12-31
Completion pushed: 2030-06-30 → 2034-12-31
NCT04888364 French Parkinson's Disease Cohort - NS-PARK · Institut National de la Santé Et de la Recherche Médicale, France
2026-08-28
Primary completion pushed: 2027-03-01 → 2027-08-15
Completion pushed: 2027-03-01 → 2027-08-15
NCT07399496 Accelerated rTMS for Apathy in Parkinson's Disease · Medical University of South Carolina
2026-08-28
Primary completion pushed: 2027-12-01 → 2028-12-01
Completion pushed: 2027-12-01 → 2028-12-01
NCT06193252 Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands · Radboud University Medical Center
2026-08-27
Primary completion pushed: 2026-08 → 2027-08
Completion pushed: 2026-08 → 2027-08
NCT00575081 Physiological Brain Atlas Development · Vanderbilt University Medical Center

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-04 NCT07804615 A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With… Vima Therapeutics new Phase 2
2026-09-01 NCT07797790 Real-world Patient Experiences With Inbrija® Merz Therapeutics GmbH new
2026-08-31 NCT07794072 Digital Patient Engagement in Technology-Supported Neurorehabilitation Catholic University, Italy new
2026-08-27 NCT07790094 Segmental Laser Acupuncture for Constipation and Sleep in Patients With Parkinson's… China Medical University Hospital new
2026-08-26 NCT07787299 Wearable for Assessing Tremor and Continuous Health in Parkinson's Disease and Essential… Heriot-Watt University new
2026-08-25 NCT07786116 The Role of METhanogens in the PROgression Of Parkinson's Disease and Related… University of Cambridge new
2026-08-24 NCT07781696 CnF-DBS for Levodopa-Resistant FOG Iahn Cajigas new
2026-08-21 NCT07780461 Characterization and Validation of the Short Physical Performance Battery in Individuals… University of Vigo new
2026-08-20 NCT07777484 An Unblinded, Single Arm, Pilot Observational Study to Test the Safety, Tolerability… Tridem Bioscience FlexCo new Phase 1
2026-08-17 NCT07767006 Neuromodulation for Patients With Parkinson's Disease Felipe Fregni, MD, PhD, MPH new

Active trials by phase

Early Phase 1
17
Phase 1
58
Phase 1/2
27
Phase 2
72
Phase 2/3
8
Phase 3
16
Phase 4
22
Not charted: 882 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 1,102

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT06234995 Cortical Electrophysiology of Response Inhibition in Parkinson's Disease Emory University Recruiting 2026-09-03
NCT06013956 Personalized Real-Time DBS and PD Mechanisms David Escobar Recruiting 2026-08-20
NCT04373317 Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis VA Office of Research and Development Recruiting 2026-08-19
NCT06951906 Imaging Biomarkers of FOG Response to DBS Medical University of South Carolina Recruiting 2026-08-10
NCT05357612 Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients… Vanderbilt University Medical Center Recruiting 2026-08-07
NCT07138560 BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease The Cleveland Clinic Recruiting 2026-06-23
NCT07284290 Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body… Virginia Commonwealth University Recruiting 2026-03-06
NCT06634641 Clozapine-related Immunodeficiency in Parkinsons Disease Centre Hospitalier Universitaire, Amiens Recruiting 2025-11-19
NCT05590637 Comparing Antipsychotic Medications in LBD Over Time The University of Texas Health Science Center at San Antonio Recruiting 2025-09-09
NCT06765668 A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants… Impax Laboratories, LLC Recruiting 2025-08-24
NCT06710574 Multimodal Image Technologies Investigate the Role and Mechanism of Probiotics in… Beijing Friendship Hospital Recruiting 2024-12-02
NCT06316232 DBS and Levodopa for Treating Freezing of Gait in Parkinson's Disease IRCCS Istituto delle Scienze Neurologiche di Bologna Recruiting 2024-03-18
NCT03495024 Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological… Corporal Michael J. Crescenz VA Medical Center Recruiting 2019-03-22
NCT07793461 Gastrointestinal Dopamine Decarboxylase and Levodopa Pharmacokinetics Beth Israel Deaconess Medical Center Not Yet Recruiting 2026-08-28
NCT05514106 MIBG in Aging and Neurologic Disorders Mayo Clinic Enrolling by Invitation 2026-07-30
NCT07187466 Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease VA Office of Research and Development Not Yet Recruiting 2026-07-22
NCT07384429 Effects of Lemborexant on Motor-sleep Comorbidity in Parkinson's Disease YangPan Not Yet Recruiting 2026-06-11
NCT07627529 Pilot Deprescribing of Antimuscarinic Overactive Bladder Medications in Parkinson Disease Corporal Michael J. Crescenz VA Medical Center Not Yet Recruiting 2026-06-04
NCT07483398 RELIEF-PD: Crisugabalin for Nociplastic Pain in Parkinson's Disease Guangdong Provincial People's Hospital Active, Not Recruiting 2026-03-19
NCT01453127 DaTSCAN Imaging in Aging and Neurodegenerative Disease Mayo Clinic Enrolling by Invitation 2026-03-10
NCT02670161 Quality Improvement and Practice Based Research in Neurology Using the EMR Endeavor Health Enrolling by Invitation 2025-08-24
NCT06805266 Vortioxetine for Depressive Symptoms and Freezing of Gait in Parkinson Disease Marianna Amboni Not Yet Recruiting 2025-02-06
Phase 3
NCT07174310 A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in… Hoffmann-La Roche Recruiting 2026-09-03
NCT04664634 A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's Northwestern University Recruiting 2026-08-24
NCT07761936 Safinamide vs Placebo for Pain in Patients With Parkinson's Disease and Motor Fluctuations Universita di Verona Recruiting 2026-08-13
See all 1,102 active Parkinson's Disease trials with filters →

Top sponsors by active trials in this area

University of Minnesota (17) · VA Office of Research and Development (13) · Ruijin Hospital (12) · Radboud University Medical Center (11) · InSightec (10) · Vanderbilt University Medical Center (10) · AbbVie (9) · Stanford University (9) · University of Alabama at Birmingham (9) · Washington University School of Medicine (9)

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