Clinical Trial

Serotonin Release in Premotor and Motor PD

Study acronym: FOX3
Recruiting
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Record status
This record was last updated October 7, 2025 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
In this study, the investigators aim to provide a deeper understanding of Parkinson's disease and find a biomarker of Parkinson's disease. This is done using imaging scans called Positron Emission tomography (PET), Single Photon Emission Computed Tomography (SPECT), and Magnetic Resonance Imaging (MRI). The findings will provide a deeper understanding of the brain changes in Parkinson's disease. More importantly, this study will help with the discovery and development of new medications aiming to delay progression of Parkinson's disease symptoms
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2022-08-24; most recent amendment 2025-10-01.
Trial Details
NCT Number NCT05516732
Lead Sponsor University of Exeter
Conditions Parkinson Disease, Parkinson's, Parkinson's Disease, Neurodegenerative Diseases, Neurodegeneration, Positron Emission Tomography
Enrollment 42 participants
Start Date 2022-07-01
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2025-10-07