Feasibility of a Community-Based Multimodal Exercise Programme in Parkinson's Disease

This study aims to evaluate the feasibility and preliminary effectiveness of a multimodal, group-based but individualised therapeutic exercise programme for people with Parkinson's disease delivered within a real-world community-based patient association setting. The primary objective is to assess the feasibility of implementing the programme, including recruitment, consent, adherence, intervention completion, acceptability, perceived exertion and safety. Secondary objectives are to obtain preliminary comparative information regarding the effects of the intervention on motor and non-motor symptoms, physical fitness, pain-related outcomes and exercise-induced hypoalgesia. This is a non-randomized sequential feasibility study including an intervention group participating in a 12-week multimodal exercise programme and a matched non-exercise control group maintaining usual activities. Outcomes will be assessed at baseline, post-intervention and 6-month follow-up.

NCT Number	NCT07618728
Lead Sponsor	Universidad Rey Juan Carlos Collaborators: Asociación Parkinson Madrid
Conditions	PARKINSON DISEASE (Disorder)
Enrollment	64 participants
Start Date	2025-09-08
Primary Completion	2026-06 (estimated)
Study Completion	2027-09 (estimated)
Updated on ClinicalTrials.gov	2026-06-03