University of Minnesota clinical trial pipeline

30 trials changed in the last 30 days: 1 stopped, 17 with notable changes, 12 with minor changes only.

1. Stopped

   Technical Development of Multi-Parametric Renocerebral MRI

   Recruitment suspended

   Sponsor's reason: Due to funding issus

   University of Minnesota·Not specified· NCT02831335· Registry history of NCT02831335 on ClinicalTrials.gov (opens the registry)

   Updated Oct 14, 2026

2. Notable

   Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca…Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter · a Hip Fracture

   Primary completion pushed from Oct 1, 2026 to Oct 1, 2027

   University of Minnesota·Phase 4· NCT06278987· Registry history of NCT06278987 on ClinicalTrials.gov (opens the registry)

   Updated Oct 13, 2026

3. Notable

   Total Contact Soft Cast in Diabetic Foot Ulcers

   Primary and study completion pushed from Oct 1, 2026 to Oct 1, 2027

   University of Minnesota·Not applicable· NCT04210089· Registry history of NCT04210089 on ClinicalTrials.gov (opens the registry)

   Updated Oct 2, 2026

4. Notable

   SGLT2 Inhibitor Therapy in Cystic Fibrosis-related Diabetes

   Primary endpoint(s) modified

   Also in this update: Results posted: Sep 21, 2026

   University of Minnesota·Phase 2/3· NCT06149793· Registry history of NCT06149793 on ClinicalTrials.gov (opens the registry)

   Updated Sep 21, 2026

5. Notable

   Targeting Transdiagnostic Self-regulatory Factors and Eating…Targeting Transdiagnostic Self-regulatory Factors and Eating Disorder Pathology · BInge-spectrum Eating disOrders: A mHEALTH Interoceptive Exposure Intervention (the Bio-HEALTH Study)

   Primary endpoint(s) modified

   Also in this update: Enrollment reduced: 144 → 80 participants

   University of Minnesota·Not applicable· NCT06631729· Registry history of NCT06631729 on ClinicalTrials.gov (opens the registry)

   Updated Sep 29, 2026

6. Notable

   Tyrannosaurus Flex: Finding the "Fair-ly Normal" Grip

   Recruitment opened

   University of Minnesota·Not applicable· NCT07735195· Registry history of NCT07735195 on ClinicalTrials.gov (opens the registry)

   Updated Oct 7, 2026

7. Notable

   Vertical Sleeve Gastrectomy and Lifestyle Modification…Vertical Sleeve Gastrectomy and Lifestyle Modification · Non-Alcoholic Steatohepatitis

   Reclassified as terminated (was completed)

   Sponsor's reason: Study has been terminated due to poor recruitment and early evidence of futility

   And 3 more changes in the last 30 days

   University of Minnesota·Not applicable· NCT03587831· Registry history of NCT03587831 on ClinicalTrials.gov (opens the registry)

   Updated Sep 30, 2026

8. Notable

   CR DBS PD · Coordinated Reset Deep Brain Stimulation for…CR DBS PD · Coordinated Reset Deep Brain Stimulation for Parkinson's Disease

   Start date pushed from Oct 10, 2026 to Dec 1, 2026

   University of Minnesota·Phase 1· NCT07340073· Registry history of NCT07340073 on ClinicalTrials.gov (opens the registry)

   Updated Oct 13, 2026

9. Notable

   Optimization of Deep Brain Stimulation Parameters · Medically…Optimization of Deep Brain Stimulation Parameters · Medically Refractory Epilepsy

   Enrollment increased: 20 → 30 participants

   Also in this update: Interventions modified; Trial arms changed: 3 → 4

   University of Minnesota·Early Phase 1· NCT05493722· Registry history of NCT05493722 on ClinicalTrials.gov (opens the registry)

   Updated Oct 13, 2026

10. Notable

    Quit With Sense: Using Mindful Smoking and Wearable Device for…Quit With Sense: Using Mindful Smoking and Wearable Device for Smoking Cessation

    Start date pushed from Oct 10, 2026 to Nov 10, 2026

    University of Minnesota·Not applicable· NCT07789496· Registry history of NCT07789496 on ClinicalTrials.gov (opens the registry)

    Updated Oct 13, 2026

11. Notable

    MN-SPEEDI · NICU-to-Home Dyadic Support for Very Preterm…MN-SPEEDI · NICU-to-Home Dyadic Support for Very Preterm Infants and Families

    Start date pushed from Oct 1, 2026 to Nov 16, 2026

    University of Minnesota·Not applicable· NCT07820462· Registry history of NCT07820462 on ClinicalTrials.gov (opens the registry)

    Updated Oct 9, 2026

12. Notable

    Histoplasmosis Induction and Consolidation Therapy Factorial…Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT)

    Start date pushed from Oct 1, 2026 to Nov 1, 2026

    University of Minnesota·Phase 3· NCT07261150· Registry history of NCT07261150 on ClinicalTrials.gov (opens the registry)

    Updated Oct 2, 2026

13. Notable

    Monitoring for CardioToxicity Using WeArable deVices While…Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE)

    Start date pushed from Sep 15, 2026 to Oct 29, 2026

    University of Minnesota·Not applicable· NCT07776964· Registry history of NCT07776964 on ClinicalTrials.gov (opens the registry)

    Updated Oct 6, 2026

14. Notable

    SERENITY · Chronic Pain Interference in Adults

    Start date pushed from Oct 1, 2026 to Nov 1, 2026

    University of Minnesota·Not specified· NCT07820475· Registry history of NCT07820475 on ClinicalTrials.gov (opens the registry)

    Updated Oct 6, 2026

15. Notable

    BOG DBS · Bayesian Optimization of DBS for Gait

    Start date pushed from Sep 2026 to Dec 2026

    University of Minnesota·Early Phase 1· NCT07835308· Registry history of NCT07835308 on ClinicalTrials.gov (opens the registry)

    Updated Sep 28, 2026

16. Notable

    Microbiota Transplant With Antibiotic Preconditioning and Fiber…Microbiota Transplant With Antibiotic Preconditioning and Fiber Supplementation in PAH

    Start date pushed from Apr 1, 2026 to Sep 1, 2026

    And 1 more change in the last 30 days

    University of Minnesota·Phase 1· NCT07751120· Registry history of NCT07751120 on ClinicalTrials.gov (opens the registry)

    Updated Sep 28, 2026

17. Notable

    Dietary Phosphorus on Phosphorus and Calcium Whole-Body Balance…Dietary Phosphorus on Phosphorus and Calcium Whole-Body Balance and Kinetics in Moderate CKD

    Start date pushed from Oct 1, 2026 to Nov 1, 2026

    University of Minnesota·Not applicable· NCT06712719· Registry history of NCT06712719 on ClinicalTrials.gov (opens the registry)

    Updated Oct 2, 2026

18. Notable

    Uncuffed Endotracheal Tube vs. no Endotracheal Tube

    Results posted: Sep 22, 2026

    University of Minnesota·Not applicable· NCT06799455· Registry history of NCT06799455 on ClinicalTrials.gov (opens the registry)

    Updated Sep 22, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.