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PTSD clinical trials

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Data updated daily from ClinicalTrials.gov, last refresh 2026-11-05

What changed in the last 30 days

43 trials changed in the last 30 days: 2 stopped, 19 with notable changes, 22 with minor changes only.

  1. Stopped: PRECLIP · Predictability of the Clinical Global Impression Scale (CGI) in Post Immediate in Psychotraumatic Impact Trial terminated Centre Hospitalier ArrasNot specified NCT05358067
  2. Notable: Deep Brain Reorienting in Post-traumatic Stress Disorder Primary and study completion pushed from Jul 2027 to Jul 2028 London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sNot applicable NCT04317820
  3. Minor: TRATT_AOS · Trauma-Related Attributions in Trauma Treatment: An Observational Study Trial completed Reinier van ArkelNot specified NCT07908186
  4. Minor: EMPOWER-2 · TSND-201 · PTSD Trial sites expanded: 6 → 9 locations Transcend TherapeuticsPhase 3 NCT07836647
  5. Stopped: TMS_AUD+mTBI · RTMS for AUD+mTBI Trial terminated VA Office of Research and DevelopmentPhase 2 NCT03995173
  6. Notable: SMART · Studying the Modification of Attention Bias Remotely After Trauma Results posted: Oct 30, 2026 University of California, San FranciscoNot applicable NCT04888169
  7. Minor: PPP · Improving Student Mental Health Through a Universal Trauma-Informed Intervention Enrollment closed, study ongoing Johns Hopkins Bloomberg School of Public HealthNot applicable NCT07842432
  8. Notable: REST · Recovering Sleep After Trauma Primary and study completion pushed from Sep 2026 to Sep 2027 University of North Carolina, Chapel HillNot applicable NCT07196332
  9. Notable: CF-CPT · Case Formulation Approach to Cognitive Processing Therapy Results posted: Oct 29, 2026 VA Office of Research and DevelopmentNot applicable NCT04407767
  10. Minor: FAM-ICU · Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study Completed without a posted recruiting period Herlev HospitalNot applicable NCT06974214
  11. Minor: CBT vs. Supportive Texts for PTSD & Hazardous Drinking (Project Better Study 2) Trial completed University of WashingtonNot applicable NCT06648395
  12. Notable: CBD-PE · Cannabidiol and Prolonged Exposure Results posted: Oct 28, 2026 VA Office of Research and DevelopmentPhase 2 NCT03518801
  13. Notable: Salience Network Informed rTMS for PTSD Phase changed: Phase 2 → Not applicable VA Office of Research and DevelopmentNot applicable NCT07886840
  14. Minor: SEVEN · Selective Glucocorticoid Receptor Antagonist · Veterans With Posttraumatic Stress Disorder (PTSD) (Seven Study) Trial completed VA Office of Research and DevelopmentPhase 2 NCT04452500
  15. Minor: Coaching Into Care With VA-CRAFT to Promote Veteran Engagement in PTSD Care Trial completed VA Office of Research and DevelopmentNot applicable NCT04501328
  16. Notable: Tele Vs. Clinic TF-CBT in Puerto Rico Primary and study completion pushed from Sep 30, 2026 to Sep 30, 2028 Medical University of South CarolinaNot applicable NCT06332209
  17. Minor: VNS mTBI · Vagal Nerve Stimulation in mTBI Trial completed VA Office of Research and DevelopmentNot applicable NCT04437498
  18. Minor: OASIS · Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL) Primary and study completion pushed from Sep 2026 to Nov 2026 University of North Carolina, Chapel HillPhase 2 NCT06636786
  19. Notable: Group-based Stabilization and Skill Training · Lasting Posttraumatic Reactions in Mental Health Care Primary completion pushed from Jun 2026 to Aug 2027 St. Olavs HospitalNot applicable NCT03887559
  20. Minor: Exercise and Emotional Learning in Posttraumatic Stress Disorder Primary completion pushed from Sep 30, 2026 to Oct 30, 2026 Christal L BadourNot applicable NCT06127342
  • Stopped: terminated, suspended or withdrawn
  • Notable: the plan changed
  • Minor: routine updates

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-10-28 NCT07900841 FUS Neuromodulation for PTSD West Virginia University new
2026-10-19 NCT07880340 Deep TMS for PTSD With Suicidal Ideation D.R. Rut Zaks OHAYON new
2026-10-14 NCT07872761 Mindful RAVANS Study Spaulding Rehabilitation Hospital new
2026-10-07 NCT07863089 RECONNECT - Treatments for Complex PTSD University of Copenhagen new
2026-09-25 NCT07840417 Deep Brain Reorienting for Posttraumatic Stress Disorder University of Alberta new
2026-09-18 NCT07827508 Assessment of Childbirth-Related Post-Traumatic Stress Disorder Groupe Hospitalier de la Region de Mulhouse et Sud Alsace new
2026-09-16 NCT07823361 The Effects of Trauma-informed Care Organization on Birth Professionals and Women's… Tarsus University new
2026-09-10 NCT07813962 Dexmedetomidine Combined With Transcutaneous Vagus Nerve Stimulation (taVNS) Can Reduce… Affiliated Hospital of Nantong University new
2026-09-10 NCT07812987 Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health Tactical Mind Research Coalition, Inc. new
2026-09-03 NCT07802158 Discontinuing Psychotropic Medication Before Psychotherapy for PTSD Academic Centre for Dentistry in Amsterdam new

Active trials by phase

Early Phase 1
10
Phase 1
14
Phase 1/2
4
Phase 2
67
Phase 2/3
6
Phase 3
19
Phase 4
14
Not charted: 536 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).
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