Piloting Novel Interventional Strategies to Improve Nicotine Pouches as a Substitute for Smoking

Some people who smoke cigarettes try to switch to oral nicotine pouches but are not able to fully stop smoking. This study tests two new strategies for people who previously tried to switch using nicotine pouches. Participants who were unable to fully switch will either be asked to increase the nicotine strength of their pouches or to use a nicotine patch along with pouches. The goal of the study is to see whether these strategies are feasible, acceptable, and helpful, and to inform the design of larger future studies.

NCT Number	NCT07625956
Lead Sponsor	Medical University of South Carolina
Conditions	Smoking ( Cigarette)
Enrollment	10 participants
Start Date	2026-06-26
Primary Completion	2026-10 (estimated)
Study Completion	2026-10 (estimated)
Updated on ClinicalTrials.gov	2026-07-06