McMaster University clinical trial pipeline

18 trials changed in the last 30 days: 1 stopped, 13 with notable changes, 4 with minor changes only.

1. Stopped

   ANTI-GLIDE · MPFL Reconstruction Versus Rehabilitation

   Withdrawn before enrolling

   Sponsor's reason: No participants recruited

   Also in this update: Primary completion date changed from estimate of Dec 31, 2027 to Oct 5, 2026

   McMaster University·Not applicable· NCT06926699· Registry history of NCT06926699 on ClinicalTrials.gov (opens the registry)

   Updated Oct 7, 2026

2. Notable

   DRIVE-UP · Vancomycin Efficacy · Ulcerative Colitis and Primary…DRIVE-UP · Vancomycin Efficacy · Ulcerative Colitis and Primary Sclerosing Cholangitis

   Primary completion pushed from Dec 2026 to Dec 2027

   Also in this update: Recruitment opened; Completion pushed from Mar 2027 to Dec 2027

   McMaster University·Phase 2· NCT07341282· Registry history of NCT07341282 on ClinicalTrials.gov (opens the registry)

   Updated Oct 9, 2026

3. Notable

   Ketorolac Versus Corticosteroid Injections for Sacroiliac Joint…Ketorolac Versus Corticosteroid Injections for Sacroiliac Joint Pain

   Primary and study completion pushed from Jun 2026 to Jul 2028

   Also in this update: Recruitment opened

   McMaster University·Early Phase 1· NCT06081101· Registry history of NCT06081101 on ClinicalTrials.gov (opens the registry)

   Updated Oct 9, 2026

4. Notable

   REPAIR · AMIC Compared With Microfracture for Focal Articular…REPAIR · AMIC Compared With Microfracture for Focal Articular Cartilage Damage of the Hip

   Primary completion pushed from Jan 1, 2026 to Jun 1, 2027

   Also in this update: Completion pushed from Jan 1, 2027 to Dec 1, 2027

   McMaster University·Phase 1· NCT05402072· Registry history of NCT05402072 on ClinicalTrials.gov (opens the registry)

   Updated Oct 7, 2026

5. Notable

   IBD · Serotonin Signalling in IBD Patients

   Primary and study completion pushed from May 2026 to Nov 2027

   McMaster University·Not specified· NCT01650311· Registry history of NCT01650311 on ClinicalTrials.gov (opens the registry)

   Updated Oct 9, 2026

6. Notable

   CADET-DCM · Conservative Care Versus Decompression Trial for…CADET-DCM · Conservative Care Versus Decompression Trial for Degenerative Cervical Myelopathy Pilot

   Primary and study completion pushed from Jun 2027 to Jun 2028

   McMaster University·Not applicable· NCT07358273· Registry history of NCT07358273 on ClinicalTrials.gov (opens the registry)

   Updated Oct 7, 2026

7. Notable

   Community-Integrated Isometric Handgrip Exercise Program and Its…Community-Integrated Isometric Handgrip Exercise Program and Its Preliminary Effects on Blood Pressure and Cognitive Function in Older Adults

   Primary and study completion pushed from Sep 15, 2026 to Apr 15, 2027

   Also in this update: Recruitment opened

   McMaster University·Not applicable· NCT07648498· Registry history of NCT07648498 on ClinicalTrials.gov (opens the registry)

   Updated Oct 7, 2026

8. Notable

   PROMPTCohort · ArthroscoPic Stabilization veRsus rehabilitatiOn…PROMPTCohort · ArthroscoPic Stabilization veRsus rehabilitatiOn of the Shoulder · a trauMatic First-time Anterior Shoulder Dislocation ePisode

   Primary completion pushed from Apr 1, 2028 to Dec 31, 2029

   Also in this update: Completion pushed from Aug 1, 2028 to Dec 31, 2029

   McMaster University·Not applicable· NCT07459777· Registry history of NCT07459777 on ClinicalTrials.gov (opens the registry)

   Updated Oct 7, 2026

9. Notable

   Long-IBD · Longitudinal Study on Bacterial Production of LPC and…Long-IBD · Longitudinal Study on Bacterial Production of LPC and LPA · Inflammatory Bowel Disease

   Primary completion pushed from Oct 31, 2024 to Mar 30, 2027

   Also in this update: Start date pushed from Dec 1, 2023 to Dec 1, 2024; Trial status changed: Unknown → Recruiting

   McMaster University·Not specified· NCT06548399· Registry history of NCT06548399 on ClinicalTrials.gov (opens the registry)

   Updated Oct 1, 2026

10. Notable

    ORDERed · Optimized Recruitment to Drive Equitable Research in…ORDERed · Optimized Recruitment to Drive Equitable Research in Stroke, Empowering Decision-making (ORDERed)

    Recruitment opened

    McMaster University·Not applicable· NCT07576647· Registry history of NCT07576647 on ClinicalTrials.gov (opens the registry)

    Updated Oct 9, 2026

11. Notable

    MIRROR · Mindfulness in Fracture Recovery and Reduction of Opioid…MIRROR · Mindfulness in Fracture Recovery and Reduction of Opioid Reliance: Evaluating the Feasibility of Implementing a Brief, Mindfulness-based Intervention to Manage Pain and Anxiety Before and After Fracture Surgery

    Recruitment opened

    Also in this update: Primary completion pushed from Oct 30, 2026 to Nov 30, 2026; Completion pushed from Oct 30, 2026 to Jan 30, 2027

    McMaster University·Not applicable· NCT07486505· Registry history of NCT07486505 on ClinicalTrials.gov (opens the registry)

    Updated Oct 7, 2026

12. Notable

    SHAPE · Skin Health and Allergy Prevention Exposure

    Recruitment opened

    McMaster University·Not applicable· NCT07489040· Registry history of NCT07489040 on ClinicalTrials.gov (opens the registry)

    Updated Oct 6, 2026

13. Notable

    UD · Revisiting the Universal Donor: Does Exposure to O Blood…UD · Revisiting the Universal Donor: Does Exposure to O Blood Products Affect Patient Outcomes?

    Primary completion date changed from estimate of Jul 2025 to Feb 16, 2026

    Also in this update: Trial completed; Final enrollment: 11 participants (planned 30)

    McMaster University·Not applicable· NCT04859218· Registry history of NCT04859218 on ClinicalTrials.gov (opens the registry)

    Updated Oct 8, 2026

14. Notable

    Exercise-Induced Lactate and Cognitive Function (ExLBC)

    Primary completion date changed from estimate of Jul 30, 2025 to Mar 30, 2026

    Also in this update: Trial status changed: Unknown → Active, Not Recruiting; Completion pushed from Sep 20, 2025 to Feb 20, 2027

    McMaster University·Not applicable· NCT06817681· Registry history of NCT06817681 on ClinicalTrials.gov (opens the registry)

    Updated Oct 7, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.