ClinicalTrials.gov term: Pulmonary Disease, Chronic Obstructive
70 trials changed in the last 30 days: 0 stopped, 33 with notable changes, 37 with minor changes only.
Primary and study completion pushed from Dec 2025 to Dec 2028
Also in this update: Interventions modified
The Foundation for Orthopaedics and Regenerative MedicinePhase 1 NCT05147688 Registry history of NCT05147688 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Feb 2026 to Dec 2027
Also in this update: Trial status changed: Unknown → Recruiting; Study completion pushed from Aug 2026 to Jun 2028
Hangzhou Broncus Medical Co., Ltd.Not applicable NCT05799664 Registry history of NCT05799664 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Sep 30, 2026 to Apr 30, 2027
AstraZenecaNot specified NCT07315958 Registry history of NCT07315958 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Aug 31, 2027 to Aug 31, 2028
VA Office of Research and DevelopmentNot applicable NCT05986214 Registry history of NCT05986214 on ClinicalTrials.gov (opens the registry)
Primary endpoint(s) modified
Also in this update: Trial completed
Joincare Pharmaceutical Group Industry Co., LtdPhase 2 NCT07440524 Registry history of NCT07440524 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from May 31, 2027 to Feb 29, 2028
Central Denmark RegionPhase 4 NCT05703919 Registry history of NCT05703919 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Feb 2026 to Feb 2027
Also in this update: Trial status changed: Unknown → Recruiting
University Hospital, MontpellierPhase 4 NCT04339270 Registry history of NCT04339270 on ClinicalTrials.gov (opens the registry)
Primary and study completion pushed from Aug 2026 to Aug 2030
Also in this update: Sponsor changed: Russell Richardson to D. Walter Wray
D. Walter WrayPhase 1 NCT02966665 Registry history of NCT02966665 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Aug 4, 2025 to May 4, 2027
Also in this update: Primary endpoint(s) modified; Trial status changed: Recruiting → Not Yet Recruiting
Istinye UniversityNot applicable NCT07185178 Registry history of NCT07185178 on ClinicalTrials.gov (opens the registry)
Primary endpoint(s) modified
Also in this update: Recruitment opened; Trial sites reduced: 79 → 54 locations
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Phase 3 NCT07464587 Registry history of NCT07464587 on ClinicalTrials.gov (opens the registry)
Primary endpoint(s) modified
Aarhus University HospitalNot specified NCT04932811 Registry history of NCT04932811 on ClinicalTrials.gov (opens the registry)
Primary endpoint(s) modified
Also in this update: Start date pushed from Aug 1, 2026 to Oct 26, 2026; Enrollment increased: 502 → 560 participants
Capital Development Authority (CDA)Not applicable NCT07708337 Registry history of NCT07708337 on ClinicalTrials.gov (opens the registry)
Primary endpoint(s) modified
Also in this update: Primary completion pushed from Dec 31, 2026 to Mar 31, 2027; Interventions modified
University of LeicesterNot applicable NCT07500948 Registry history of NCT07500948 on ClinicalTrials.gov (opens the registry)
Phase changed: Phase 4 → not specified
Also in this update: Trial completed; Study completion date changed from estimate of May 1, 2026 to Jun 1, 2026
Iuliu Hatieganu University of Medicine and PharmacyNot specified NCT07362173 Registry history of NCT07362173 on ClinicalTrials.gov (opens the registry)
Recruitment opened
CSL BehringPhase 4 NCT07326592 Registry history of NCT07326592 on ClinicalTrials.gov (opens the registry)
Recruitment opened
Regeneron PharmaceuticalsPhase 4 NCT07587658 Registry history of NCT07587658 on ClinicalTrials.gov (opens the registry)
Sponsor changed: S-INFINITY Pharmaceuticals Co., Ltd to Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
Also in this update: Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.Phase 1 NCT07035652 Registry history of NCT07035652 on ClinicalTrials.gov (opens the registry)
Recruitment opened
Also in this update: Trial sites expanded: 0 → 4 locations
GlaxoSmithKlinePhase 3 NCT07780656 Registry history of NCT07780656 on ClinicalTrials.gov (opens the registry)
Recruitment opened
Also in this update: Trial sites expanded: 0 → 3 locations; Start date changed from estimate of Sep 14, 2026 to Sep 16, 2026
SanofiPhase 3 NCT07793409 Registry history of NCT07793409 on ClinicalTrials.gov (opens the registry)
Recruitment opened
Eli Lilly and CompanyPhase 2 NCT07759245 Registry history of NCT07759245 on ClinicalTrials.gov (opens the registry)
Completed without a posted recruiting period
Also in this update: Primary completion date changed from estimate of Dec 2026 to Oct 9, 2026
AeroRx Therapeutics Inc.Phase 1 NCT07802730 Registry history of NCT07802730 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Study completion date changed from estimate of Jan 2027 to Aug 5, 2026
Grifols Therapeutics LLCPhase 3 NCT01983241 Registry history of NCT01983241 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Primary completion pushed from Dec 2026 to Mar 1, 2027; Study completion moved earlier from Jun 2027 to Mar 1, 2027
Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USAPhase 2 NCT05270525 Registry history of NCT05270525 on ClinicalTrials.gov (opens the registry)
Trial status changed: Enrolling by Invitation → Recruiting
Also in this update: Interventions modified; and 1 more change in the last 30 days
Beijing Chao Yang HospitalNot specified NCT07701096 Registry history of NCT07701096 on ClinicalTrials.gov (opens the registry)
Trial completed
AstraZenecaNot specified NCT07221981 Registry history of NCT07221981 on ClinicalTrials.gov (opens the registry)
Trial completed
AstraZenecaNot specified NCT06646419 Registry history of NCT06646419 on ClinicalTrials.gov (opens the registry)
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Green International UniversityNot applicable NCT07752420 Registry history of NCT07752420 on ClinicalTrials.gov (opens the registry)
Enrollment closed, study ongoing
Also in this update: Primary completion pushed from Jul 2026 to Dec 2026; Study completion pushed from Jul 2026 to Dec 2027
Maastricht University Medical CenterNot applicable NCT03807310 Registry history of NCT03807310 on ClinicalTrials.gov (opens the registry)
Trial completed
Vejle HospitalPhase 3 NCT06473701 Registry history of NCT06473701 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Primary completion date changed from estimate of Feb 2026 to Apr 10, 2026; Final enrollment: 439 participants (planned 490)
Monash UniversityNot applicable NCT04217330 Registry history of NCT04217330 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Dec 31, 2026 to Apr 1, 2027
Also in this update: Study completion pushed from May 1, 2027 to May 31, 2027
CSA Medical, Inc.Not applicable NCT07468617 Registry history of NCT07468617 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 294 → 314 locations
And 1 more change in the last 30 days
SanofiPhase 3 NCT07190209 Registry history of NCT07190209 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Jan 31, 2027 to Jun 1, 2027
Also in this update: Study completion pushed from Jan 31, 2027 to Jan 31, 2028
Icahn School of Medicine at Mount SinaiNot applicable NCT06634810 Registry history of NCT06634810 on ClinicalTrials.gov (opens the registry)
Sponsor refiled this as recruiting (was completed)
China-Japan Friendship HospitalNot applicable NCT05775588 Registry history of NCT05775588 on ClinicalTrials.gov (opens the registry)
Trial completed
Also in this update: Study completion date changed from estimate of Jan 4, 2027 to Sep 21, 2026
University of LeedsNot applicable NCT07181915 Registry history of NCT07181915 on ClinicalTrials.gov (opens the registry)
Enrollment increased: 150 → 166 participants
AstraZenecaPhase 4 NCT06531798 Registry history of NCT06531798 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 3 → 7 locations
SanofiNot specified NCT07612878 Registry history of NCT07612878 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 276 → 284 locations
AstraZenecaPhase 3 NCT06878261 Registry history of NCT06878261 on ClinicalTrials.gov (opens the registry)
Primary completion pushed from Jul 1, 2026 to Nov 1, 2026
Also in this update: Study completion pushed from Aug 1, 2026 to Dec 1, 2026
Assiut UniversityNot specified NCT06983366 Registry history of NCT06983366 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 9 → 13 locations
UCB Biopharma SRLPhase 2 NCT07725939 Registry history of NCT07725939 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 15 → 281 locations
Also in this update: Interventions modified; Study completion moved earlier from Aug 20, 2029 to Feb 14, 2029
GlaxoSmithKlinePhase 3 NCT06959095 Registry history of NCT06959095 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 159 → 193 locations
Also in this update: Interventions modified; Study completion moved earlier from Aug 21, 2029 to Feb 14, 2029
GlaxoSmithKlinePhase 3 NCT06961214 Registry history of NCT06961214 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 214 → 315 locations
SanofiPhase 3 NCT07190222 Registry history of NCT07190222 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 68 → 82 locations
SanofiPhase 4 NCT07053423 Registry history of NCT07053423 on ClinicalTrials.gov (opens the registry)
Trial sites expanded: 22 → 28 locations
SanofiNot specified NCT07380711 Registry history of NCT07380711 on ClinicalTrials.gov (opens the registry)
Study completion pushed from Mar 2027 to Mar 1, 2029
University of NebraskaNot applicable NCT06524856 Registry history of NCT06524856 on ClinicalTrials.gov (opens the registry)
Interventions modified
Beijing Chao Yang HospitalNot specified NCT07382986 Registry history of NCT07382986 on ClinicalTrials.gov (opens the registry)
Registry marked status Unknown (sponsor has not verified the record since May 2024); last known: Active, Not Recruiting
CSA Medical, Inc.Not applicable NCT03893370 Registry history of NCT03893370 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Oct 2023); last known: Not Yet Recruiting
University Hospital, GrenoblePhase 3 NCT06212765 Registry history of NCT06212765 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical FoundationEarly Phase 1 NCT06584786 Registry history of NCT06584786 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Shanghai Chest HospitalNot specified NCT07045532 Registry history of NCT07045532 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Recruiting
Kirsehir Ahi Evran UniversitesiNot applicable NCT06707649 Registry history of NCT06707649 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting
Ningbo No. 1 HospitalNot applicable NCT06612476 Registry history of NCT06612476 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Active, Not Recruiting
University of CreteNot applicable NCT06599177 Registry history of NCT06599177 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Sep 2024); last known: Not Yet Recruiting
Ataturk UniversityNot applicable NCT06588361 Registry history of NCT06588361 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Aug 2024); last known: Not Yet Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCSNot applicable NCT06559670 Registry history of NCT06559670 on ClinicalTrials.gov (opens the registry)
Changed
Registry marked status Unknown (sponsor has not verified the record since Apr 2024); last known: Recruiting
University of TriesteNot applicable NCT06331416 Registry history of NCT06331416 on ClinicalTrials.gov (opens the registry)
Changed
Registry verification sweep
Changed
| First posted | Trial | Sponsor | Phase |
|---|---|---|---|
| 2026-10-13 | NCT07871357 Urolithin A Supplementation During Pulmonary Rehabilitation in Patients With COPD | Bryan A. Ross new | Phase 2 |
| 2026-10-09 | NCT07868211 Effect of Dietary Fiber Supplementation on Systemic Inflammation and Clinical Parameters… | Júnea Regina Pires Drews new | |
| 2026-10-09 | NCT07867184 Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES) | National Institute of Allergy and Infectious Diseases (NIAID) new | |
| 2026-10-02 | NCT07854210 HFNC Versus NIV in Hypercapneic COPD Patients | Mohammed Shehta new | |
| 2026-10-02 | NCT07856667 COINCIDE: Cardineurovascular dIsease and Obstructive Airway Disease | VASCage GmbH new | |
| 2026-10-01 | NCT07852910 Indoor Overheating and Physiological Strain in Older Adults With COPD | University of Ottawa new | |
| 2026-09-25 | NCT07842510 Controlled Versus Standard Oxygen Therapy in ICU Patients With Acute Exacerbation of COPD | Hôpital Universitaire Taher Sfar new | |
| 2026-09-23 | NCT07836764 Validation of 1 Minute Sit-to Stand Test for Assessment of Breathlessness at Exertion in… | Jacob Sandberg new | |
| 2026-09-17 | NCT07825636 Sensorimotor Function in COPD | Alanya Alaaddin Keykubat University new | |
| 2026-09-14 | NCT07818187 Effectiveness of Active Cycle of Breathing Techniques in Patients With Chronic… | National Yang Ming Chiao Tung University Hospital new |
| Early Phase 1 | 3 | |
| Phase 1 | 18 | |
| Phase 1/2 | 12 | |
| Phase 2 | 46 | |
| Phase 2/3 | 6 | |
| Phase 3 | 37 | |
| Phase 4 | 31 |
AstraZeneca (16) · Assiut University (15) · China-Japan Friendship Hospital (11) · Henan University of Traditional Chinese Medicine (11) · VA Office of Research and Development (11) · Riphah International University (10) · Haisco Pharmaceutical Group Co., Ltd. (8) · Sanofi (8) · Assistance Publique - Hôpitaux de Paris (7) · GlaxoSmithKline (7)