GlaxoSmithKline (GSK) Clinical Trial Pipeline: 165 Active Trials, 39 Changes This Month

What changed in the last 30 days

2026-09-04

Trial terminated
Trial terminated: Operational challenges
Final enrollment: 2 participants — 5% of the 40 planned
Primary completion confirmed: July 2026 (last estimated August 2028)

NCT06405230 Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Extracellular… · Phase 1/2

2026-09-01

Trial status changed: Suspended → Withdrawn

NCT07684586 A Study to Investigate the Difference In Blood Levels of Camlipixant Between Different… · Phase 1

2026-08-12

Primary completion pushed: 2026-11-30 → 2027-06-29
Completion pushed: 2026-11-30 → 2027-06-29

NCT07085702 A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of the GSK 4-component… · Phase 1

2026-08-20

Primary endpoint(s) modified
Trial sites expanded: 36 → 44 locations

NCT05714839 A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of… · Phase 1/2

2026-09-05

Enrollment reduced: 123 → 109 participants
Primary completion moved earlier: 2028-12-19 → 2027-11-24
Completion moved earlier: 2032-07-16 → 2027-11-24

NCT05334368 Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial · Phase 3

2026-09-03

Enrollment reduced: 215 → 183 participants
Trial completed
Primary completion confirmed: August 2026 (last estimated September 2026)

NCT06213506 A Study on the Safety, Reactogenicity, and Immune Response to the GVGH iNTS-GMMA Vaccine… · Phase 2

2026-08-21

Enrollment reduced: 1808 → 1456 participants
Trial arms changed: 43 → 26

NCT07628049 A Study of Investigational RSV/hMPV Combination and Investigational hMPV Vaccines in… · Phase 1/2

2026-08-13

Enrollment reduced: 446 → 363 participants
Trial sites expanded: 46 → 134 locations

NCT07201051 A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With… · Phase 2

2026-09-02

Enrollment closed, study ongoing
Trial sites reduced: 114 → 109 locations
Final enrollment: 303 participants (planned 350)
Completion pushed: 2029-05-29 → 2029-07-17

NCT06411249 A Study Describing the Efficacy and Safety of Belimumab Administered in Adult… · Phase 4

2026-08-27

Recruitment opened
Enrollment increased: 30 → 34 participants
Trial sites expanded: 0 → 3 locations
Primary completion moved earlier: 2029-03-19 → 2027-03-01
Completion moved earlier: 2029-03-19 → 2028-11-24

NCT07671001 A Study of Depemokimab in Participants of 6 to 11 Years of Age · Phase 3

2026-08-20

Recruitment opened
Trial sites expanded: 2 → 17 locations

NCT07585266 A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With… · Phase 3

2026-08-18

Enrollment closed, study ongoing

NCT07596173 A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria… · Phase 3

2026-09-02

Interventions modified

NCT07684599 A Study to Investigate Mocertatug Rezetecan as Maintenance Treatment for Participants… · Phase 3

2026-08-18

Primary completion pushed: 2030-07-08 → 2030-09-23
Trial sites expanded: 8 → 17 locations
Completion pushed: 2030-07-08 → 2030-09-23

NCT07456033 A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and… · Phase 3

2026-09-01

Trial sites expanded: 18 → 28 locations

NCT07286331 A Study to Investigate Mocertatug Rezetecan Compared With Chemotherapy in Participants… · Phase 3

2026-09-01

Trial sites expanded: 126 → 132 locations

NCT07099898 A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) · Phase 3

2026-08-26

Trial sites expanded: 51 → 59 locations

NCT07227311 A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With… · Phase 2

2026-08-20

Completion pushed: 2027-04-26 → 2027-09-30

NCT04179032 Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus… · Phase 2

New trial filings, last 30 days

First posted	Trial	Phase	Status
2026-09-04	NCT07805707 A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age	Phase 3	Not Yet Recruiting
2026-09-03	NCT07802704 A Study of Risvutatug Rezetecan in Participants With Metastatic Castration-resistant…	Phase 3	Not Yet Recruiting
2026-08-27	NCT07789899 A Study to Evaluate Pharmacokinetics, Safety, and Tolerability of Two GSK3862995B…	Phase 1	Recruiting
2026-08-27	NCT07791043 A Study to Investigate the Safety and Efficacy of Efimosfermin Alfa Compared With Placebo…	Phase 2	Not Yet Recruiting
2026-08-25	NCT07784894 A Study to Investigate the Repeat-dose Pharmacokinetics of a Combined Oral Contraceptive…	Phase 1	Not Yet Recruiting
2026-08-24	NCT07782957 A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With…	Phase 3	Not Yet Recruiting
2026-08-24	NCT07782970 A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants…	Phase 3	Not Yet Recruiting
2026-08-24	NCT07782996 A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in…	Phase 3	Not Yet Recruiting
2026-08-21	NCT07780643 A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in…	Phase 3	Not Yet Recruiting
2026-08-21	NCT07780656 A Study to Investigate the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared…	Phase 3	Not Yet Recruiting

Active trials by phase

Phase 1		35
Phase 1/2		21
Phase 2		36
Phase 2/3		3
Phase 3		59
Phase 4		9

Not charted: 2 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 165

NCT ID	Title	Condition	Status	Updated
Phase 4
NCT07502560	A Study to Evaluate the Effect of Recombinant Zoster Vaccine on New Diagnosis of Dementia…	Herpes Zoster	Recruiting	2026-05-12
NCT06411249	A Study Describing the Efficacy and Safety of Belimumab Administered in Adult…	Systemic Lupus Erythematosus	Active, Not Recruiting	2026-09-01
NCT07701967	Efficacy and Safety of Depemokimab Monotherapy Without Concomitant Use of Intranasal…	Nasal Polyps	Not Yet Recruiting	2026-07-14
NCT07652515	A Study to Evaluate the Safety of Dostarlimab in Adult Participants in India With Primary…	Neoplasms, Endometrial	Not Yet Recruiting	2026-06-17
NCT06113198	A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup…	Meningitis, Meningococcal	Active, Not Recruiting	2026-04-06
NCT06372496	Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care…	Asthma	Active, Not Recruiting	2026-03-24
NCT06041386	REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment…	Asthma	Active, Not Recruiting	2025-08-01
NCT06897527	A Study to Evaluate the Safety of Dostarlimab in Adult Participants in India With…	Neoplasms, Endometrial	Not Yet Recruiting	2025-07-08
NCT06887933	A Trial to Evaluate the Safety of Niraparib Tablets in Adult Female Participants With…	Ovarian Neoplasms	Not Yet Recruiting	2025-03-21
Phase 3
NCT05334368	Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial	Hypereosinophilic Syndrome	Recruiting	2026-09-04
NCT07099898	A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC)	Neoplasms, Lung	Recruiting	2026-08-31
NCT07286331	A Study to Investigate Mocertatug Rezetecan Compared With Chemotherapy in Participants…	Neoplasms, Endometrial	Recruiting	2026-08-31
NCT07671001	A Study of Depemokimab in Participants of 6 to 11 Years of Age	Asthma	Recruiting	2026-08-26
NCT07585266	A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With…	Gastrointestinal Stromal Neoplasms	Recruiting	2026-08-19
NCT07456033	A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and…	Asthma	Recruiting	2026-08-17
NCT07701993	A Pivotal Clinical Study to Investigate the Safety and Efficacy of Efimosfermin Compared…	Metabolic Dysfunction-associated Steatohepatitis	Recruiting	2026-08-05
NCT07704892	A Study to Investigate Safety and Efficacy of Efimosfermin Compared With Placebo in Adult…	Metabolic Dysfunction-associated Steatohepatitis	Recruiting	2026-08-05
NCT07177339	eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic…	Pulmonary Disease, Chronic Obstructive	Recruiting	2026-07-28
NCT07596199	A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria…	Diphtheria-Tetanus-acellular Pertussis Vaccines	Recruiting	2026-07-28
NCT07221188	A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa…	Non-alcoholic Fatty Liver Disease	Recruiting	2026-07-27
NCT07221227	A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With…	Non-alcoholic Fatty Liver Disease	Recruiting	2026-07-27
NCT05757102	A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in…	Asthma	Recruiting	2026-07-16
NCT07286266	A Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in…	Ovarian Neoplasms	Recruiting	2026-07-15
NCT07406360	A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps…	Measles	Recruiting	2026-07-08
NCT06979323	Depemokimab Asthma Imaging and Bronchoscopy Sub-Study	Asthma	Recruiting	2026-07-02

See all 165 active GlaxoSmithKline (GSK) trials with filters →

Disease areas by active trials, top 10 of 23

Multiple Myeloma (20) · Asthma (12) · NASH / MASH (8) · Lupus (SLE) (5) · Ovarian Cancer (5) · Lung Cancer (3) · Alzheimer's Disease (2) · Head & Neck Cancer (2) · Myelofibrosis (2) · Sarcoma (2)

GlaxoSmithKline (GSK) clinical trial pipeline

What changed in the last 30 days

New trial filings, last 30 days

Active trials by phase

Active trials top 25 of 165

Disease areas by active trials, top 10 of 23