ClinicalTrials.gov term: Non-alcoholic Fatty Liver Disease

Disease landscape

NASH / MASH clinical trials

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-20

What changed in the last 30 days

43 trials changed in the last 30 days: 0 stopped, 14 with notable changes, 29 with minor changes only.

  1. Notable

    DeepUSFF · Quantitative Ultrasound (RS85 and R20) for Liver Fat Quantification in MASLD Using MRI-PDFF as Reference

    Enrollment increased: 62 → 182 participants

    Also in this update: Enrollment closed, study ongoing; Study completion pushed from Jun 30, 2026 to Dec 30, 2026

    Seoul National University HospitalNot applicable NCT07192159 Registry history of NCT07192159 on ClinicalTrials.gov (opens the registry)

Show 29 trials with minor changes only
  1. Minor

    SAVID-SLD · Samsung S-Viscosity vs Canon Dispersion Slope in Steatotic Liver Disease (SAVID-SLD)

    Trial status changed: Not Yet Recruiting → Active, Not Recruiting

    Also in this update: Study completion pushed from Feb 28, 2027 to Dec 30, 2027; Primary completion moved earlier from Dec 30, 2026 to Oct 7, 2026

    Seoul National University HospitalNot specified NCT07530419 Registry history of NCT07530419 on ClinicalTrials.gov (opens the registry)

  2. Minor
    7 trials marked Unknown by the registry's verification sweep

    Registry verification sweep

    Changed

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-10-19 NCT07881796 Effect of Dapagliflozin on Metabolic Parameters in Patients With Non-Alcoholic Fatty… Shalamar Hospital new
2026-10-16 NCT07878091 A Phase 2a Study of Kylo-0603 Capsule in Participants With Metabolic Dysfunction… Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. new Phase 2
2026-10-16 NCT07877272 Endohepatology-Based Reclassification of Treatment Indication in High-Risk MASLD University Hospital Muenster new
2026-10-08 NCT07865936 Cardiovascular Risk Assessment and Coronary Calcium Score in Thai MASLD Patients Watcharasak Chotiyaputta new
2026-10-06 NCT07861191 RESET-INSPIRE Study: Insulin Sensitivity & Population Intervention With Real-time… National University Health System, Singapore new
2026-10-06 NCT07860814 Ultrasound Biomarkers for Assessing Eligibility and Response to Resmetirom Therapy Radnet Management, Inc. new
2026-09-22 NCT07833514 Misocholic Tablets for Non-Viral Elevated Liver Enzymes Hanoi Medical University new Phase 3
2026-09-16 NCT07821749 A Prospective Study of Cold Exposure in Patients With MASH Renmin Hospital of Wuhan University new
2026-09-11 NCT07816211 External Transportability Validation, Implementation Readiness, and Outcome Association… Anhui Provincial Hospital new
2026-09-03 NCT07801313 Phase 1 Clinical Study of MWN105 Injection in Healthy Chinese Volunteers Shanghai Minwei Biotechnology Co., Ltd new Phase 1

Active trials by phase

Early Phase 1
7
Phase 1
24
Phase 1/2
9
Phase 2
68
Phase 3
29
Phase 4
22
Not charted: 368 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Top sponsors by active trials in this area

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