352 active trials 176 recruiting 17 Phase 3 48 disease areas 39 changes in 30 days
21 trials changed in the last 30 days: 1 stopped, 6 with notable changes, 14 with minor changes only.
Trial terminated
Sponsor's reason: Investigator transition
Also in this update: Primary completion pushed from Jun 30, 2020 to Sep 28, 2026; Final enrollment: 23 participants (planned 30)
University of PennsylvaniaNot applicable NCT03081390 Registry history of NCT03081390 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion pushed from Oct 23, 2026 to Oct 23, 2027
Also in this update: Completion pushed from Oct 23, 2026 to Oct 23, 2028
University of PennsylvaniaPhase 1 NCT03721822 Registry history of NCT03721822 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Jun 30, 2026 to Jun 30, 2027
University of PennsylvaniaNot applicable NCT04024631 Registry history of NCT04024631 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Jan 2027 to Jan 2028
University of PennsylvaniaNot specified NCT04251130 Registry history of NCT04251130 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment reduced: 390 → 262 participants
University of PennsylvaniaNot applicable NCT06843213 Registry history of NCT06843213 on ClinicalTrials.gov (opens the registry)
Updated
Recruitment opened
University of PennsylvaniaPhase 2 NCT07489430 Registry history of NCT07489430 on ClinicalTrials.gov (opens the registry)
Updated
Enrolling by invitation only
University of PennsylvaniaNot applicable NCT07265375 Registry history of NCT07265375 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Final enrollment: 19 participants (planned 50)
University of PennsylvaniaNot specified NCT06807840 Registry history of NCT06807840 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Final enrollment: 54 participants (planned 60); Study completion date changed from estimate of Dec 31, 2026 to Aug 15, 2026
University of PennsylvaniaNot applicable NCT06356168 Registry history of NCT06356168 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Study completion date changed from estimate of Apr 25, 2027 to Apr 20, 2026
University of PennsylvaniaNot applicable NCT07154888 Registry history of NCT07154888 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Final enrollment: 8 participants (planned 34); Primary completion date changed from estimate of Aug 1, 2026 to Apr 8, 2026
University of PennsylvaniaNot applicable NCT07158736 Registry history of NCT07158736 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
University of PennsylvaniaNot applicable NCT07226492 Registry history of NCT07226492 on ClinicalTrials.gov (opens the registry)
Updated
Enrollment closed, study ongoing
Also in this update: Primary completion pushed from Aug 15, 2026 to Dec 15, 2026; Completion pushed from Aug 15, 2026 to Jan 31, 2027
University of PennsylvaniaPhase 2 NCT06066957 Registry history of NCT06066957 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
University of PennsylvaniaPhase 2 NCT05632315 Registry history of NCT05632315 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Sep 15, 2026 to Dec 15, 2026
University of PennsylvaniaEarly Phase 1 NCT06788249 Registry history of NCT06788249 on ClinicalTrials.gov (opens the registry)
Updated
Trial completed
Also in this update: Final enrollment: 32 participants (planned 60)
University of PennsylvaniaNot applicable NCT06904898 Registry history of NCT06904898 on ClinicalTrials.gov (opens the registry)
Updated
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
University of PennsylvaniaNot applicable NCT07773753 Registry history of NCT07773753 on ClinicalTrials.gov (opens the registry)
Updated
Primary and study completion pushed from Nov 2026 to Jan 2027
University of PennsylvaniaNot applicable NCT07553559 Registry history of NCT07553559 on ClinicalTrials.gov (opens the registry)
Updated
Completion pushed from Sep 1, 2026 to Jan 30, 2027
University of PennsylvaniaEarly Phase 1 NCT06419335 Registry history of NCT06419335 on ClinicalTrials.gov (opens the registry)
Updated
Completion pushed from Jul 31, 2026 to Dec 31, 2026
University of PennsylvaniaEarly Phase 1 NCT05967195 Registry history of NCT05967195 on ClinicalTrials.gov (opens the registry)
Updated
Primary completion moved earlier from Mar 24, 2027 to Sep 24, 2026
University of PennsylvaniaNot applicable NCT05360849 Registry history of NCT05360849 on ClinicalTrials.gov (opens the registry)
Updated
| First posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-10-07 | NCT07862439 Biomarker-guided Reduction of Immunosuppression in Liver Transplant Recipients (BRITRE) | Phase 2 | Not Yet Recruiting |
| 2026-10-07 | NCT07862452 Tracking Income Dynamics and Everyday Health Study | Not Yet Recruiting | |
| 2026-09-21 | NCT07830771 Fibroblast Activating Protein (FAP) PET/CT in Adults With Tuberculosis | Early Phase 1 | Recruiting |
| 2026-09-17 | NCT07825571 The Gender Inclusive Sexuality Talks Program | Recruiting |
| Early Phase 1 | 21 | |
| Phase 1 | 29 | |
| Phase 1/2 | 8 | |
| Phase 2 | 30 | |
| Phase 2/3 | 9 | |
| Phase 3 | 8 | |
| Phase 4 | 13 |
| NCT ID | Title | Condition | Status | Updated |
|---|---|---|---|---|
| Phase 4 | ||||
| NCT07542756 | A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications… | Insomnia | Recruiting | 2026-09-16 |
| NCT07777926 | Evaluation of Filler Injection for Chin Profile Enhancement | Chin Regression | Recruiting | 2026-08-20 |
| NCT06665997 | Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With… | Sickle Cell Disease (SCD) | Recruiting | 2026-05-28 |
| NCT06073665 | Dosing of LT4 in Older Individuals | Hypothyroidism | Recruiting | 2026-02-19 |
| NCT06954129 | A Pragmatic Clinical Trial Comparing the Risk of Acute Kidney Injury During Treatment… | Acute Kidney Injury | Recruiting | 2026-02-13 |
| NCT05108818 | Characterization of Humoral and Cellular Immune Responses Elicited by Influenza… | Influenza, Human | Recruiting | 2026-02-09 |
| NCT05028062 | Naltrexone in AUD Reward Drinkers | Alcohol Use Disorder | Recruiting | 2026-01-20 |
| NCT07518901 | Nanozymes in Endodontics | Apical Periodontitis | Enrolling by Invitation | 2026-08-31 |
| NCT04582383 | Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne | Acne | Active, Not Recruiting | 2026-08-25 |
| NCT05730205 | Effects of the Contraceptive Implant in Women With Sickle Cell Disease | Sickle Cell Disease | Active, Not Recruiting | 2026-06-12 |
| NCT04961190 | A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for… | Posttraumatic Stress Disorder | Active, Not Recruiting | 2026-06-09 |
| NCT04323189 | Effects of Sitagliptin in Individuals With Genetically Decreased DPP4 | Genetics Disease | Active, Not Recruiting | 2026-01-16 |
| NCT03315975 | Flu Vaccine Responses in the Setting of Melanoma Treatment | Viral Vaccines | Active, Not Recruiting | 2025-08-19 |
| Phase 3 | ||||
| NCT05456503 | PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620 | Frontotemporal Lobar Degeneration | Recruiting | 2026-09-21 |
| NCT06408181 | APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia | Pre-Eclampsia | Recruiting | 2026-09-10 |
| NCT07265830 | Building Adaptive School-based Interventions for Caries | Dental Caries | Recruiting | 2026-09-10 |
| NCT04474847 | Abatacept for the Treatment of Giant Cell Arteritis | Giant Cell Arteritis | Recruiting | 2026-08-20 |
| NCT06167746 | iCare4Me Transitions | Caregiver Stress | Recruiting | 2026-03-12 |
| NCT05669833 | Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients | Psoriatic Arthritis | Recruiting | 2025-10-09 |
| NCT07506512 | Optimal Time Interval Between Mifepristone and Misoprostol Administration for Early… | Early Pregnancy Loss | Not Yet Recruiting | 2026-10-09 |
| NCT06596577 | Nudging Effective and Equitable Delivery of Specialty Palliative Care | Serious Illness | Enrolling by Invitation | 2026-04-30 |
| Phase 2/3 | ||||
| NCT06815237 | Effects of Ketone Supplement and Alcohol on Brain Metabolism | Ketosis | Recruiting | 2026-03-25 |
| NCT04616781 | Ketone Ester Intervention in Alcohol Use Disorder | Alcohol Drinking | Recruiting | 2026-02-09 |
| NCT03143374 | PET Tau - Neurodegenerative Disease Imaging | Neurodegenerative Disease | Recruiting | 2025-10-15 |
| NCT06559995 | Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol… | Alcohol Use Disorder | Recruiting | 2025-09-15 |
Depression (10) · Diabetes (10) · Stroke (10) · Alzheimer's Disease (8) · Chronic Kidney Disease (8) · Heart Failure (8) · Hypertension (8) · Breast Cancer (7) · Anxiety (5) · Dementia (5)