Disease landscape

Chronic Kidney Disease clinical trials

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990 active trials 508 recruiting 70 Phase 3 566 sponsors 117 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-05

What changed in the last 30 days showing 46 of 117 changes on 19 trials

2026-09-03
Trial status changed: Suspended → Withdrawn
NCT07020832 Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults at High Risk of… · Apellis Pharmaceuticals, Inc. · Phase 3
2026-09-04
Primary completion pushed: 2027-02 → 2027-08
Completion pushed: 2027-05 → 2027-08
NCT06390592 Clinical Performance of the Therapy Option FlexPoint of the PD Cycler Sleep•Safe Harmony · Fresenius Medical Care Deutschland GmbH
2026-08-14
Primary completion pushed: 2026-07-01 → 2026-12-01
Completion pushed: 2026-07-01 → 2026-12-01
NCT07262333 A Trial of Hydroxynidone Capsules in Single-dose Administration for Patients With Renal… · Beijing Continent Pharmaceutical Co, Ltd. · Phase 1
2026-09-05
Primary completion pushed: 2026-06 → 2027-01
Completion pushed: 2026-12 → 2027-06
NCT06823115 Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0 · Indiana University
2026-09-05
Primary completion pushed: 2027-12 → 2028-05
Primary endpoint(s) modified
Recruitment opened
Completion pushed: 2027-12 → 2028-05
NCT06327750 The Microcirculation, Dialysis Modality and Sequestered Salt · Amsterdam UMC, location VUmc
2026-08-18
Primary completion pushed: 2026-03 → 2026-07-24
Enrollment reduced: 244 → 210 participants
Trial completed
Trial sites reduced: 21 → 18 locations
Completion pushed: 2026-03 → 2026-07-24
NCT05489120 Low-Protein Diet With Low-Protein Foods Versus a LPD Without LP Foods in Patients With… · Dr. Schär AG / SPA
2026-08-14
Primary completion pushed: 2024-12-02 → 2026-12-01
NCT04802395 Real World Evidence Clinical Utility Study of KidneyIntelX · Renalytix AI, Inc.
2026-08-28
Primary completion pushed: 2028-05 → 2029-02
Completion pushed: 2028-08 → 2030-02
NCT07325201 Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous… · HealthPartners Institute · Phase 2
2026-08-27
Primary completion pushed: 2025-12-30 → 2026-06-30
Primary endpoint(s) modified
Enrollment reduced: 60 → 20 participants
Trial completed
Completion moved earlier: 2026-12-30 → 2026-07-30
NCT04212923 eHealth Based Self-management Intervention for Chronic Kidney Disease Care in China · Leiden University Medical Center
2026-08-25
Primary completion pushed: 2026-01-15 → 2026-05-15
Trial completed
Completion pushed: 2026-04-15 → 2026-08-19
NCT07256613 Non-surgical Periodontal Therapy and Kidney Outcomes in Type 2 Diabetes Mellitus · Dow University of Health Sciences
2026-08-20
Primary completion pushed: 2026-06-01 → 2026-09-01
Completion pushed: 2026-07-01 → 2026-11-01
NCT06430684 Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic… · Ann & Robert H Lurie Children's Hospital of Chicago · Early Phase 1
2026-08-12
Primary completion pushed: 2026-06 → 2026-10-30
NCT05705414 Oral Intradialytic Amino Acid Supplementation to Vitalize End-stage Kidney Disease… · The University of Texas Health Science Center at San Antonio · Early Phase 1
2026-08-13
Primary completion pushed: 2025-02-28 → 2025-12-01
Enrollment reduced: 720 → 556 participants
Trial completed
Completion pushed: 2025-12-01 → 2025-12-31
NCT06833541 Research on Gut Microbiota and Metabolomics in Diabetic Kidney Disease · The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2026-08-11
Primary completion pushed: 2026-05-01 → 2026-09-01
NCT03253172 Potassium Supplementation in CKD · Erasmus Medical Center
2026-08-14
Primary endpoint(s) modified
Trial sites expanded: 1 → 59 locations
NCT07481526 A Prospecitve Multicenter, Observational Registry Study · AstraZeneca
2026-09-03
Primary endpoint(s) modified
Trial completed
Enrollment increased: 206 → 280 participants
Results posted: 2026-09-02
Primary completion confirmed: June 2025 (last estimated March 2026)
NCT04910867 APOL1 Genetic Testing Program for Living Donors · Northwestern University
2026-09-01
Primary endpoint(s) modified
NCT06781294 SIRAKI 02 Posthoc Analysis. · Hospital Universitari de Bellvitge
2026-08-29
Primary endpoint(s) modified
NCT07175896 Dine and DASH Into Wellness Pilot Study · Duke University
2026-08-20
Primary endpoint(s) modified
NCT07325201 Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous… · HealthPartners Institute · Phase 2
2026-08-11
Enrollment reduced: 280 → 220 participants
NCT04634916 Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System · C. R. Bard

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-04 NCT07803900 Effect of Synchronized Transcutaneous Electrical Diaphragm Stimulation Using Surged… Maharashtra University of Health Sciences new
2026-09-04 NCT07804316 Fostering Self-Empowerment in CKD Patients Through Food Choice Mapping Singapore Institute of Technology new
2026-09-03 NCT07801937 Family TIME: A Family-focused Nursing Intervention for Adults Receiving Haemodialysis and… University of Southern Denmark new
2026-08-31 NCT07793929 A Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics (PK) of… Kailera new Phase 1
2026-08-28 NCT07792317 Hypothermic Machine Perfusion With Omnisol of Deceased Donor Kidneys Prior to… Vivalyx GmbH new
2026-08-25 NCT07784452 Comparing Hepatitis B Vaccination Schedules in Patients on Hemodialysis Jinnah Hospital new
2026-08-25 NCT07786168 Roxadustat Versus Erythropoietin for Anaemia Treatment in Diabetic Nephropathy Hanzla Arshad new
2026-08-20 NCT07775482 Finerenone for AKI: a Multicenter, Randomized, Placebo-Controlled Feasibility Pilot Trial Jean-Maxime Côté new
2026-08-20 NCT07776925 Effects of Maqui Supplementation on Gut Microbiota, Inflammation, and Oxidative Stress in… Universidad Mayor new
2026-08-20 NCT07777523 Non-invasive Testing for End-Stage Chronic Kidney Disease Gisens Biotech new

Active trials by phase

Early Phase 1
12
Phase 1
37
Phase 1/2
30
Phase 2
61
Phase 2/3
5
Phase 3
65
Phase 4
70
Not charted: 710 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 990

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07380113 Anrikefon vs Nalfurafine for Sleep Quality in Hemodialysis Patients With CKD-aP Zhujiang Hospital Recruiting 2026-08-25
NCT06110130 Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With… Washington D.C. Veterans Affairs Medical Center Recruiting 2026-08-21
NCT07741292 Niaoduqing Granules in Older Adults With Impaired Kidney Function Huashan Hospital Recruiting 2026-08-03
NCT06396416 Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2 Western University, Canada Recruiting 2026-06-29
NCT07017270 Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis Unity Health Toronto Recruiting 2026-06-26
NCT06860711 Safety of Short-course of NSAIDs in Pediatric Patients With CKD University of Colorado, Denver Recruiting 2026-06-08
NCT05671991 Effect of Empagliflozin on Peritoneal and Kidney Function in End Stage Renal Disease Yale University Recruiting 2026-05-22
NCT03862859 The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With… Nicholas Carlson Recruiting 2026-05-19
NCT06560801 Dapagliflozin on Renal Morphology and Renal Perfusion in Patients One Year After Kidney… University of Erlangen-Nürnberg Medical School Recruiting 2026-05-06
NCT07405216 Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Adolescents With… Centenario Hospital Miguel Hidalgo Recruiting 2026-04-27
NCT06013865 Empagliflozin Treatment in Kidney Transplant Recipients VA Office of Research and Development Recruiting 2026-04-21
NCT06712407 Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With… Calliditas Therapeutics AB Recruiting 2026-02-05
NCT06256991 Potassium Correction for RAAS Optimization in Chronic Kidney Disease University Medical Center Groningen Recruiting 2025-12-19
NCT07259512 Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease… Evi Liliek Wulandari Recruiting 2025-12-10
NCT07271420 Blood Pressure Control With Thiazide Diuretics in Peritoneal Dialysis Patients Chinese University of Hong Kong Recruiting 2025-12-09
NCT07239570 A Biomarker-targeted Clinical Trial to Optimize Treatment for Patients With Chronic… Peter Rossing Recruiting 2025-11-20
NCT04381143 ASPIrin in Reducing Events in Dialysis ( ASPIRED ) Guangdong Provincial People's Hospital Recruiting 2025-11-18
NCT07187713 ACE Reno, Pico Cell Matrix and Its Effect on eGFR in Chronic Kidney Diseases Ace Cells Lab Limited Recruiting 2025-09-23
NCT07182942 The Effect and Mechanism of Xiqing Regulating Intestinal Homeostasis on Drug Efficacy of… Chujin Cao Recruiting 2025-09-19
NCT07030894 Nefecon and Ambrisentan in IgA Nephropathy The First Hospital of Jilin University Recruiting 2025-09-15
NCT06701825 Effectiveness and Cost-effectiveness of a Pre-emptive Genotyping Strategy in Patients… Instituto de Investigación Hospital Universitario La Paz Recruiting 2025-09-11
NCT03991169 Oral Iron in Children With Chronic Kidney Disease Weill Medical College of Cornell University Recruiting 2025-08-11
NCT06725810 Correction of Anemia With Enarodustat in Non-dialysis Dependent Chronic Kidney Disease Shanghai Zhongshan Hospital Recruiting 2025-07-28
NCT06676384 Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can… Christian Medical College, Vellore, India Recruiting 2025-07-14
NCT05942053 Role of Vitamin K2 in Chronic Kidney Disease Tanta University Recruiting 2025-06-24
See all 990 active Chronic Kidney Disease trials with filters →

Top sponsors by active trials in this area

Assiut University (17) · VA Office of Research and Development (12) · AstraZeneca (11) · Universidade Federal Fluminense (10) · Bayer (9) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (9) · National Taiwan University Hospital (9) · Sohag University (9) · University of Pennsylvania (9) · Mansoura University (8)

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