Bayer Clinical Trial Pipeline: 87 Active Trials, 28 Changes This Month

17 trials changed in the last 30 days: 0 stopped, 3 with notable changes, 14 with minor changes only.

Notable

MOSAIC-TTR · Acoramidis · Transthyretin Amyloid Cardiomyopathy

Recruitment opened

BayerNot specified NCT07791160 Registry history of NCT07791160 on ClinicalTrials.gov (opens the registry)

Updated Sep 15, 2026
Notable

ARASEC · Darolutamide Administered Together With Androgen Deprivation Therapy (ADT) Works · Metastatic Hormone-sensitive Prostate Cancer. Results Will be Compared With ADT Alone From a Previously Conducted Study

Results posted: Sep 15, 2026

Also in this update: Trial completed

BayerPhase 2 NCT05059236 Registry history of NCT05059236 on ClinicalTrials.gov (opens the registry)

Updated Sep 15, 2026
Notable

RELIEF · How Elinzanetant is Used and How Well it Works · Menopause Symptoms in United States

Enrollment increased: 1500 → 2400 participants

BayerNot specified NCT07490431 Registry history of NCT07490431 on ClinicalTrials.gov (opens the registry)

Updated Sep 24, 2026

Show 14 trials with minor changes only

Minor

Called FINE-REAL Korea to Learn More About the Use of the Drug Finerenone · Chronic Kidney Disease and Type 2 Diabetes in a Routine Medical Care Setting in South Korea

Enrollment closed, study ongoing

BayerNot specified NCT07232537 Registry history of NCT07232537 on ClinicalTrials.gov (opens the registry)

Updated Oct 8, 2026
Minor

RE-ENGAGE · Treatment Patterns and Factors Determining the Choice of Treatment in Canadian · Metastatic Hormone Sensitive Prostate Cancer in Routine Medical Care

Trial completed

Also in this update: Primary completion date changed from estimate of Dec 31, 2026 to Jun 30, 2026; Final enrollment: 477 participants (planned 700)

BayerNot specified NCT06874114 Registry history of NCT06874114 on ClinicalTrials.gov (opens the registry)

Updated Oct 6, 2026
Minor

How Well · Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a "Shuttle

Trial completed

BayerPhase 1/2 NCT03588299 Registry history of NCT03588299 on ClinicalTrials.gov (opens the registry)

Updated Sep 23, 2026
Minor

ASSESS · How Well BAY 3401016 Works · Alport Syndrome

Enrollment closed, study ongoing

Also in this update: Interventions modified

BayerPhase 2 NCT07211685 Registry history of NCT07211685 on ClinicalTrials.gov (opens the registry)

Updated Sep 18, 2026
Minor

How Safe Finerenone is and How Well it Works · Chronic Kidney Disease and Type 2 Diabetes in Routine Medical Care in the United States

Trial completed

Also in this update: Final enrollment: 238038 participants (planned 150000)

BayerNot specified NCT06608212 Registry history of NCT06608212 on ClinicalTrials.gov (opens the registry)

Updated Sep 24, 2026
Minor

How Safe BAY3389934 is and How it Affects Blood Clotting When Given Alone or With Aspirin in Healthy Participants

Primary and study completion pushed from Nov 11, 2026 to Dec 29, 2026

BayerPhase 1 NCT07652723 Registry history of NCT07652723 on ClinicalTrials.gov (opens the registry)

Updated Sep 23, 2026
Minor

ACO-MONITOR · Acceptance and Feasibility of a Digital Remote Monitoring Tool Configured · ATTR-CM: ACO-Monitor

Primary completion pushed from Feb 28, 2028 to Apr 15, 2028

Also in this update: Completion pushed from Mar 28, 2028 to May 15, 2028

BayerNot specified NCT07557147 Registry history of NCT07557147 on ClinicalTrials.gov (opens the registry)

Updated Sep 24, 2026
Minor

PACE mHSPC · Darolutamide Plus Androgen Deprivation Therapy · Metastatic Hormone-sensitive Prostate Cancer in India

Enrollment increased: 50 → 60 participants

Also in this update: Start date pushed from Oct 5, 2026 to Oct 15, 2026

BayerNot specified NCT07806591 Registry history of NCT07806591 on ClinicalTrials.gov (opens the registry)

Updated Oct 6, 2026
Minor

SOHO-02 · How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, · Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

Enrollment increased: 444 → 555 participants

BayerPhase 3 NCT06452277 Registry history of NCT06452277 on ClinicalTrials.gov (opens the registry)

Updated Sep 23, 2026
Minor

ACO-REAL · Use of Acoramidis · a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting

Trial sites expanded: 1 → 17 locations

Also in this update: Completion moved earlier from Jul 3, 2028 to Apr 30, 2028

BayerNot specified NCT07235462 Registry history of NCT07235462 on ClinicalTrials.gov (opens the registry)

Updated Oct 8, 2026
Minor

FIONA OLE · How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Trial sites expanded: 133 → 151 locations

Also in this update: Completion moved earlier from Nov 7, 2028 to Aug 31, 2028; Primary completion moved earlier from Oct 8, 2028 to Aug 1, 2028

BayerPhase 3 NCT05457283 Registry history of NCT05457283 on ClinicalTrials.gov (opens the registry)

Updated Sep 16, 2026
Minor

Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activity · Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

Trial sites reduced: 28 → 17 locations

BayerPhase 1 NCT06052306 Registry history of NCT06052306 on ClinicalTrials.gov (opens the registry)

Updated Sep 24, 2026
Minor

CARDIOVERT · How Well BAY 3670549 Works and How Safe it is · Atrial Fibrillation

Start date pushed from Aug 18, 2026 to Sep 1, 2026

BayerPhase 2 NCT07625215 Registry history of NCT07625215 on ClinicalTrials.gov (opens the registry)

Updated Oct 6, 2026
Minor

PATENT-CHILD · Riociguat · Pulmonary Arterial Hypertension (PAH)

Completion pushed from Aug 3, 2027 to May 15, 2028

BayerPhase 3 NCT02562235 Registry history of NCT02562235 on ClinicalTrials.gov (opens the registry)

Updated Sep 23, 2026

Stopped: an ongoing trial was terminated, suspended or withdrawn.
Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Minor: routine progress and housekeeping, such as sites added or enrollment closed.

NCT ID	Title	Condition	Status	Updated
Phase 4
NCT07298044	A Study to Learn More About the Change in the Blood Levels of Transthyretin When…	Transthyretin Amyloid Cardiomyopathy	Recruiting	2026-09-25
NCT05348876	A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real…	Non-metastatic Castration-resistant Prostate Cancer	Recruiting	2026-07-06
NCT04597125	RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs…	Metastatic Castrate Resistant Prostate Cancer (mCRPC)	Active, Not Recruiting	2026-07-06
Phase 3
NCT05457283	A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use…	Chronic Kidney Disease	Recruiting	2026-09-24
NCT06452277	A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With…	Advanced Non-small Cell Lung Cancer, HER2 Mutation	Recruiting	2026-09-23
NCT07192952	A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time…	Left Ventricular Systolic Dysfunction	Recruiting	2026-06-29
NCT07188805	A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves…	Left Ventricular Systolic Dysfunction	Recruiting	2026-06-15
NCT02562235	Riociguat in Children With Pulmonary Arterial Hypertension (PAH)	Hypertension, Pulmonary	Active, Not Recruiting	2026-09-23
NCT05196035	A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it…	Chronic Kidney Disease	Active, Not Recruiting	2026-08-28
NCT05587296	A Study to Learn More About How Well Elinzanetant Works and How Safe it is Compared to…	Vasomotor Symptoms Caused by Adjuvant Endocrine Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer	Active, Not Recruiting	2026-07-09
NCT04464226	Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in…	Cancer	Active, Not Recruiting	2026-07-07
NCT05794906	A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) and Placebo…	Biochemically Recurrent Prostate Cancer	Active, Not Recruiting	2026-07-07
NCT07023341	A Study to Learn More About How Well Aficamten Works in Japanese Participants With…	Obstructive Hypertrophic Cardiomyopathy	Active, Not Recruiting	2026-06-26
Phase 2
NCT07625215	A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial…	Atrial Fibrillation	Recruiting	2026-10-06
NCT06760819	A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets…	Advanced Solid Tumors	Recruiting	2026-10-02
NCT07450599	A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy…	High-risk Localized Prostate Cancer	Recruiting	2026-08-10
NCT06246643	A Study of Continued Treatment With Regorafenib in Participants With Solid Tumors Who…	Solid Malignant Tumors	Active, Not Recruiting	2026-09-23
NCT07211685	A Study to Learn About How Well BAY 3401016 Works in Adults With Alport Syndrome	Alport Syndrome	Active, Not Recruiting	2026-09-18
NCT07566429	A Study of AB-1005 Gene Therapy in Japanese Adults With Moderate Parkinson's Disease…	Parkinson Disease	Not Yet Recruiting	2026-07-29
Phase 1/2
NCT06914128	A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors	MTAP-deleted Solid Tumors	Recruiting	2026-09-10
NCT05099172	First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung…	Advanced Non-small Cell Lung Cancer	Recruiting	2026-08-12
NCT02637687	A Study to Test the Safety and Efficacy of the Drug Larotrectinib for the Treatment of…	Solid Tumors Harboring NTRK Fusion	Active, Not Recruiting	2025-06-22
Phase 1
NCT07535112	A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With…	Advanced/Metastatic Colorectal Adenocarcinoma	Recruiting	2026-10-05
NCT06659341	A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have…	Advanced Solid Tumors Harboring KRAS G12C Mutation	Recruiting	2026-09-23
NCT06854640	A Study to Learn About How Safe BAY 3389934 is, Its Suitable Dose, and How it Affects the…	Sepsis	Recruiting	2026-09-23

Bayer clinical trial pipeline

What changed in the last 30 days

MOSAIC-TTR · Acoramidis · Transthyretin Amyloid Cardiomyopathy

ARASEC · Darolutamide Administered Together With Androgen Deprivation Therapy (ADT) Works · Metastatic Hormone-sensitive Prostate Cancer. Results Will be Compared With ADT Alone From a Previously Conducted Study

RELIEF · How Elinzanetant is Used and How Well it Works · Menopause Symptoms in United States

Called FINE-REAL Korea to Learn More About the Use of the Drug Finerenone · Chronic Kidney Disease and Type 2 Diabetes in a Routine Medical Care Setting in South Korea

RE-ENGAGE · Treatment Patterns and Factors Determining the Choice of Treatment in Canadian · Metastatic Hormone Sensitive Prostate Cancer in Routine Medical Care

How Well · Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a "Shuttle

ASSESS · How Well BAY 3401016 Works · Alport Syndrome

How Safe Finerenone is and How Well it Works · Chronic Kidney Disease and Type 2 Diabetes in Routine Medical Care in the United States

How Safe BAY3389934 is and How it Affects Blood Clotting When Given Alone or With Aspirin in Healthy Participants

ACO-MONITOR · Acceptance and Feasibility of a Digital Remote Monitoring Tool Configured · ATTR-CM: ACO-Monitor

PACE mHSPC · Darolutamide Plus Androgen Deprivation Therapy · Metastatic Hormone-sensitive Prostate Cancer in India

SOHO-02 · How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, · Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

ACO-REAL · Use of Acoramidis · a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting

FIONA OLE · How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activity · Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

CARDIOVERT · How Well BAY 3670549 Works and How Safe it is · Atrial Fibrillation

PATENT-CHILD · Riociguat · Pulmonary Arterial Hypertension (PAH)

New trial filings, last 30 days

Active trials by phase

Active trials top 25 of 87

Disease areas by active trials, top 10 of 19