Disease landscape

Amyloidosis clinical trials

Get alerts when Amyloidosis trials change
Data updated daily from ClinicalTrials.gov, last refresh 2026-10-20

What changed in the last 30 days

18 trials changed in the last 30 days: 3 stopped, 5 with notable changes, 10 with minor changes only.

  1. Notable

    Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 · Heart Failure Due to Transthyretin Amyloidosis

    Primary endpoint(s) modified

    Also in this update: Trial sites expanded: 35 → 38 locations; Study completion pushed from Aug 15, 2028 to Feb 9, 2030; and 1 more change in the last 30 days

    Novo Nordisk A/SPhase 2 NCT06260709 Registry history of NCT06260709 on ClinicalTrials.gov (opens the registry)

Show 10 trials with minor changes only
  1. Minor

    JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide for Multiple Myeloma, Newly Diagnosed AL Amyloidosis, and High-risk Smoldering Multiple Myeloma or JNJ-79635322 in Combination With Pomalidomide for Multiple Myeloma

    Enrollment increased: 240 → 276 participants

    And 2 more changes in the last 30 days

    Janssen Research & Development, LLCPhase 1 NCT06768489 Registry history of NCT06768489 on ClinicalTrials.gov (opens the registry)

  2. Minor
    2 trials marked Unknown by the registry's verification sweep

    Registry verification sweep

    Changed

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-10-14 NCT07874334 Phase 1a/b Study of GPRC5D CART Therapy in Relapsed/Refractory Multiple Myeloma and… Hadassah Medical Organization new Phase 1
2026-08-25 NCT07784712 Right Ventricular Septal Biopsy to Detect Cardiac Amyloidosis Geisinger Clinic new
2026-08-14 NCT07765524 A Phase I/II Open-label, Single-arm, Multicenter Clinical Study to Evaluate the Safety… Shenzhen Fosun Kairos Biotechnology Co., Ltd. new Phase 1/2
2026-08-07 NCT07752732 Non-Interventional Study on the Prevalence of Cardiac Amyloidosis in Patients With… University Hospital Tuebingen new
2026-07-23 NCT07721350 Prospective Evaluation of Subcutaneous Administration of Daratumumab by the FreedomEDGE®… Hospices Civils de Lyon new

Active trials by phase

Early Phase 1
3
Phase 1
12
Phase 1/2
13
Phase 2
41
Phase 3
25
Phase 4
9
Not charted: 154 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Top sponsors by active trials in this area

Get alerts when Amyloidosis trials change
Status changes, date slips, and new sponsor entrants: detected daily, delivered to your inbox.
Start monitoring free

Narrower conditions

Active trials