Sponsor pipeline

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's clinical trial pipeline

Get alerts when London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's's trials change

133 active trials 56 recruiting 6 Phase 3 29 disease areas 59 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days showing 44 of 59 changes on 20 trials

2026-09-23
Withdrawn before enrolling
Trial withdrawn: Was unable to achieve funding for this study
NCT06418295 Cytokine Alterations and Chronic Post-Surgical Pain
2026-10-02
Primary completion pushed: 2026-09 → 2027-09
Completion pushed: 2027-03 → 2028-03
NCT04197141 Hypofractionated Whole-Pelvis Radiotherapy (WPRT) vs Conventionally-Fractionated WPRT in… · Phase 2
2026-10-02
Primary completion pushed: 2026-07 → 2028-07
Recruitment opened
Completion pushed: 2027-07 → 2029-07
NCT04986605 Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis · Phase 2
2026-09-25
Primary completion pushed: 2030-08 → 2031-04
Completion pushed: 2030-08 → 2031-04
NCT06660277 DIALysis With EXpanded Solute Removal
2026-09-23
Primary completion pushed: 2025-12-31 → 2027-02
Completion pushed: 2026-02-28 → 2027-02
NCT05151315 NitrX Total Knee Arthroplasty RSA
2026-09-23
Primary completion pushed: 2025-11-30 → 2027-11-30
Completion pushed: 2025-11-30 → 2027-11-30
NCT05221554 Pre-Op THA Modelling
2026-09-23
Primary completion pushed: 2025-12 → 2027-12
Completion pushed: 2026-12 → 2027-12
NCT05800457 The Role of Synovectomy in Pain Reduction Following Total Knee Arthroplasty
2026-09-22
Primary completion pushed: 2027-12-01 → 2028-12-01
Recruitment opened
Completion pushed: 2027-12-31 → 2028-12-31
NCT07179991 DDAVP Effect by TEG6 in Cardiac Surgery
2026-09-22
Primary completion pushed: 2025-11-30 → 2027-11-30
Completion pushed: 2026-12-30 → 2028-12-30
NCT05375513 SYNERGIC-2 Trial (SYNchronizing, Exercises and Remedies to GaIn Cognition@Home)
2026-09-22
Primary completion pushed: 2025-12 → 2028-12
Phase changed: Phase 4 → not applicable
Completion pushed: 2025-12 → 2028-12
NCT06267482 Using ROSA for Challenging The TKA Standard of Care
2026-09-18
Primary completion pushed: 2025-08 → 2027-08
Trial status changed: Unknown → Recruiting
Completion pushed: 2025-08 → 2027-08
NCT06525610 Weight-Bearing CT Periprosthetic Distal Knee Fractures
2026-09-18
Primary completion pushed: 2027-09-01 → 2028-01-01
Completion pushed: 2027-11-01 → 2028-05-01
NCT07656636 Perforated Appendicitis and Postoperative Antibiotics Pilot Trial
2026-10-01
Trial completed
Final enrollment: 3 participants (planned 11)
Primary completion confirmed: July 2025 (last estimated February 2026)
NCT05149768 Open Label Extension Study of Brentuximab Vedotin in Early dcSSc · Phase 2
2026-09-23
Trial completed
Primary completion 2026-09-01, at least 365 days after the final estimate of 2025-09-01
Final enrollment: 15 participants (planned 27)
NCT04869436 Olfactory Outcomes of Dupilumab Treatment for Nasal Polyposis · Phase 4
2026-09-23
Recruitment opened
NCT06951477 Gut Microbiome in Orthopaedics: Revision Total Knee Arthroplasty
2026-09-23
Recruitment opened
Primary completion moved earlier: 2027-12-31 → 2027-06-30
NCT07176533 Suprazygomatic Maxillary Nerve Block in Pediatric Tonsillectomy
2026-09-23
Trial completed
Primary completion confirmed: January 2026 (last estimated December 2025)
NCT04990713 QoR40 Between Intercostal Block and Intercostal Block and Serratus Plane Catheter During…
2026-09-19
Trial completed
Final enrollment: 45 participants (planned 100)
Primary completion confirmed: April 2019 (last estimated May 2026)
NCT03275155 Pathophysiology and Risk of Atrial Fibrillation Detected After Ischemic Stroke
2026-09-19
Recruitment opened
NCT07726134 The Impact of Intraoperative Diuretic Use on Delayed Graft Function Following Deceased…
2026-09-15
Sponsor refiled this as active, not recruiting (was completed)
NCT07546643 Long-Term Risk of Gout in Living Kidney Donors

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-29 NCT07846696 An Open Label Individual Patient (OLIP)-02 Study of Nusinersen (BIIB058) Phase 3 Not Yet Recruiting
2026-09-24 NCT07838779 An OLIP Study (Open Label Individual Patient) of Nusinersen in a Participant With Spinal… Not Yet Recruiting
2026-09-22 NCT07835269 The PERK Study: Predicting and Evaluating Response to Knee RFA Using fNIRS Not Yet Recruiting

Active trials by phase

Early Phase 1
1
Phase 1
5
Phase 1/2
3
Phase 2
10
Phase 2/3
2
Phase 3
4
Phase 4
2
Not charted: 106 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 133

NCT IDTitleConditionStatusUpdated
Phase 4
NCT03976245 Advanced Therapeutics in Rheumatoid Arthritis (RA) Rheumatoid Arthritis Recruiting 2024-11-29
NCT04147013 Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients with… Chronic Rhinosinusitis with Nasal Polyps Active, Not Recruiting 2024-10-29
Phase 3
NCT04374799 Heparin vs Placebo for Cardiac Catheterization Cardiac Disease Recruiting 2026-02-20
NCT05383495 Anxiolysis for Laceration Repair in Children Laceration of Skin Recruiting 2025-04-30
NCT03895359 Transarterial Chemoembolization (TACE) Versus TACE Plus Stereotactic Body Radiation… Hepatocellular Carcinoma Recruiting 2025-03-11
NCT07846696 An Open Label Individual Patient (OLIP)-02 Study of Nusinersen (BIIB058) SMA - Spinal Muscular Atrophy Not Yet Recruiting 2026-09-29
Phase 2/3
NCT05166343 POHCA Resuscitation: Evaluation of IM Epinephrine Pediatric Out-of-Hospital Cardiac Arrest Recruiting 2025-03-11
NCT06820645 Calcium Administration in Life-saving Management During Massive Hemorrhage Massive Hemorrhage Not Yet Recruiting 2025-02-11
Phase 2
NCT04986605 Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis Diffuse Cutaneous Systemic Sclerosis Recruiting 2026-10-01
NCT07188246 Neoadjuvant, SBRT With Intratumoural Pembrolizumab Followed by Neoadjuvant Chemotherapy… Breast Cancer Recruiting 2026-02-11
NCT06262048 Prevention of Post Operative Urinary Retention After Thoracic Surgery Trial Urinary Retention Postoperative Recruiting 2024-10-28
NCT03997643 Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining… Head and Neck Cancer Recruiting 2023-08-03
NCT04583254 Hypofractionated External-beam RadiOtherapy for Intact Cervical Cancer (HEROICC-Trial): A… Cervical Cancer Recruiting 2023-05-10
NCT04220749 Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma Head and Neck Cancer Recruiting 2020-09-04
NCT04197141 Hypofractionated Whole-Pelvis Radiotherapy (WPRT) vs Conventionally-Fractionated WPRT in… Prostate Cancer Active, Not Recruiting 2026-10-01
NCT04603014 Interdialytic Peritoneal UltraFiltration in HemoDialysis Patients End Stage Renal Disease on Dialysis Active, Not Recruiting 2026-05-04
NCT07076914 Prophylactic Proton Pump Inhibition for Esophageal Protection in Lung Radiation Therapy Primary Lung Cancer Not Yet Recruiting 2025-07-22
NCT06578871 Surgery and Reducing Ionizing Radiation of the Unknown Primary Head and Neck Squamous Cell Carcinoma Not Yet Recruiting 2024-09-03
Phase 1/2
NCT06634108 Genistein in trAnSthyretin recePtor Amyloid caRdiomyopathy Amyloid Cardiomyopathy Recruiting 2025-06-15
NCT07785388 Genistein for the Reduction of Adverse Cardiovascular Events (GRACE) HIV Not Yet Recruiting 2026-08-25
NCT04405596 Ambroxol as a Novel Disease Modifying Treatment for Lewy Body Dementia Lewy Body Disease Not Yet Recruiting 2023-12-13
Phase 1
NCT04163289 Preventing Toxicity in Renal Cancer Patients Treated With Immunotherapy Using Fecal… Renal Cell Carcinoma Active, Not Recruiting 2026-10-01
NCT07654517 A Phase I Evaluation of the Safety and Tolerability of Pirfenidone in Idiopathic… Idiopathic Subglottic Stenosis Not Yet Recruiting 2026-06-17
NCT03306680 SUNSET: SBRT for Ultra-central NSCLC- a Safety and Efficacy Trial Non Small Cell Lung Cancer Active, Not Recruiting 2025-09-18
NCT03772899 Fecal Microbial Transplantation in Combination With Immunotherapy in Melanoma Patients… Melanoma Active, Not Recruiting 2025-03-28
See all 133 active London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's trials with filters →

Disease areas by active trials, top 10 of 29

Chronic Kidney Disease (16) · Lung Cancer (6) · Head & Neck Cancer (5) · Heart Disease (5) · Non-Small Cell Lung Cancer (NSCLC) (5) · Prostate Cancer (4) · Alzheimer's Disease (3) · Breast Cancer (3) · Depression (3) · PTSD (3)

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