Sponsor Pipeline

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
65
Active Trials
46
Recruiting
2
Phase 3
10
Disease Areas
8
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-13 NCT04862221
TReatment for ImmUne Mediated PathopHysiology
Enrollment reduced: 163 -> 44 participants
2026-08-11 NCT03884075
Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect…
date change Primary completion pushed: 2026-08-31 -> 2027-09-03
2026-08-11 NCT03884075
Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect…
date change Completion pushed: 2026-10-02 -> 2027-12-31
2026-07-29 NCT00739362
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
Enrollment closed, study ongoing
2026-07-29 NCT00739362
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
Enrollment reduced: 148 -> 126 participants
2026-07-29 NCT01878045
Mechanisms of Diabetic Kidney Disease in American Indians
overall status: Suspended → Completed
2026-07-29 NCT04862221
TReatment for ImmUne Mediated PathopHysiology
Enrollment closed, study ongoing
2026-07-29 NCT04862221
TReatment for ImmUne Mediated PathopHysiology
Trial sites reduced: 24 -> 17 locations
Active Trials by Phase
Phase 4
1
Phase 3
1
Phase 2/3
1
Phase 2
20
Phase 1/2
1
Phase 1
3
Not specified
38
Active Trials — top 25 of 65
NCT IDTitleConditionStatus
Phase 4
NCT03520660 People With CHC Who Achieved a Sustained Virological Response Following Therapy With… Diabetes Mellitus Active, Not Recruiting
Phase 3
NCT02262832 Compassionate Use of Metreleptin in Previously Treated People With Generalized… Lipodystrophy Active, Not Recruiting
Phase 2/3
NCT07444723 Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of… Primary Hyperparathyroidism Recruiting
Phase 2
NCT05470504 Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance Insulin Receptor Mutation Recruiting
NCT05832229 Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United… Cirrhosis Recruiting
NCT04927416 The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer Metastic Thyroid Cancer Recruiting
NCT07142252 Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus Type 1 Diabetes Mellitus Recruiting
NCT02019706 Prospective Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in… ACTH Recruiting
NCT06092333 VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B Chronic Hepatitis B Recruiting
NCT00977977 Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy Nephrotic Syndrome Recruiting
NCT03884075 Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect… Non-Alcoholic Steatohepatitis Recruiting
NCT06635629 Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome Cushing Syndrome Recruiting
NCT03841617 The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer Thyroid Cancer Recruiting
NCT00085982 Effect of Metreleptin Therapy in the Treatment of Severe Insulin Resistance Severe Insulin Resistance Active, Not Recruiting
NCT03929601 Rituximab-pvvr and Abatacept vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes Type 1 Diabetes Mellitus Active, Not Recruiting
NCT07216391 Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG Type 1 Diabetes Mellitus Not Yet Recruiting
NCT05743244 Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1… Diabetes Mellitus, Type 1 Active, Not Recruiting
NCT07683026 Platform Trial in Stage 1 Diabetes: Comparing Golimumab vs Placebo Type 1 Diabetes (T1D) Not Yet Recruiting
NCT00739362 Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment Electric Stimulation Therapy Active, Not Recruiting
NCT02262806 Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy Diabetes Active, Not Recruiting
NCT04862221 TReatment for ImmUne Mediated PathopHysiology Acute Liver Failure Active, Not Recruiting
NCT05713799 Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With… Insulin Resistance Not Yet Recruiting
NCT07313787 Effects of Meal Macronutrients on Postprandial Lipids Nephrotic Syndrome Not Yet Recruiting
Phase 1/2
NCT06991738 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive… Thyroid Cancer Not Yet Recruiting
Phase 1
NCT04799301 Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake Diet Therapy Recruiting
See all 65 active National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) trials with filters →
Disease Areas
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