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National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) clinical trial pipeline

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64 active trials 46 recruiting 13 disease areas 4 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-11

What changed in the last 30 days

3 trials changed in the last 30 days: 0 stopped, 1 with a notable change, 2 with minor changes only.

Show 2 trials with minor changes only
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

Active trials by phase

Phase 1
2
Phase 1/2
1
Phase 2
20
Phase 2/3
1
Phase 3
1
Phase 4
1
Not charted: 38 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 64

NCT IDTitleConditionStatusUpdated
Phase 4
NCT03520660 People With CHC Who Achieved a Sustained Virological Response Following Therapy With… Diabetes Mellitus Active, Not Recruiting 2026-10-02
Phase 3
NCT02262832 Compassionate Use of Metreleptin in Previously Treated People With Generalized… Lipodystrophy Active, Not Recruiting 2026-09-22
Phase 2/3
NCT07444723 Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of… Primary Hyperparathyroidism Recruiting 2026-06-02
Phase 2
NCT04927416 The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer Metastic Thyroid Cancer Recruiting 2026-10-05
NCT02019706 Prospective Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in… ACTH Recruiting 2026-10-02
NCT05832229 Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United… Cirrhosis Recruiting 2026-09-28
NCT00977977 Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy Nephrotic Syndrome Recruiting 2026-09-22
NCT03841617 The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer Thyroid Cancer Recruiting 2026-09-09
NCT07216391 Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG Type 1 Diabetes Mellitus Recruiting 2026-09-09
NCT07142252 Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus Type 1 Diabetes Mellitus Recruiting 2026-09-08
NCT06635629 Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome Cushing Syndrome Recruiting 2026-08-31
NCT05470504 Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance Insulin Receptor Mutation Recruiting 2026-08-18
NCT03884075 Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect… Non-Alcoholic Steatohepatitis Recruiting 2026-08-10
NCT05713799 Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With… Insulin Resistance Not Yet Recruiting 2026-10-09
NCT07313787 Effects of Meal Macronutrients on Postprandial Lipids Nephrotic Syndrome Not Yet Recruiting 2026-10-09
NCT00739362 Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment Electric Stimulation Therapy Active, Not Recruiting 2026-10-08
NCT02262806 Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy Diabetes Active, Not Recruiting 2026-10-08
NCT06092333 VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B Chronic Hepatitis B Active, Not Recruiting 2026-10-05
NCT05743244 Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1… Diabetes Mellitus, Type 1 Active, Not Recruiting 2026-09-02
NCT03929601 Rituximab-pvvr and Abatacept vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes Type 1 Diabetes Mellitus Active, Not Recruiting 2026-09-01
NCT04862221 TReatment for ImmUne Mediated PathopHysiology Acute Liver Failure Active, Not Recruiting 2026-08-12
NCT07683026 Platform Trial in Stage 1 Diabetes: Comparing Golimumab vs Placebo Type 1 Diabetes (T1D) Not Yet Recruiting 2026-07-06
NCT00085982 Effect of Metreleptin Therapy in the Treatment of Severe Insulin Resistance Severe Insulin Resistance Active, Not Recruiting 2025-01-30
Phase 1/2
NCT06991738 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive… Thyroid Cancer Not Yet Recruiting 2026-10-09
Phase 1
NCT04799301 Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake Diet Therapy Recruiting 2026-09-14

Disease areas by active trials, top 10 of 13

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