Disease landscape

Thyroid Cancer clinical trials

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320 active trials 177 recruiting 21 Phase 3 178 sponsors 54 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-16

What changed in the last 30 days showing 47 of 54 changes on 20 trials

2026-09-12
Recruitment suspended
Recruitment suspended: Sponsor stopped the study.
NCT07181720 CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid Tumors · Chongqing Precision Biotech Co., Ltd · Phase 1
2026-09-15
Primary completion pushed: 2026-09-30 → 2028-09-30
Completion pushed: 2026-09-30 → 2028-09-30
NCT01709292 Vemurafenib Neoadjuvant Trial in Locally Advanced Thyroid Cancer · M.D. Anderson Cancer Center · Phase 2
2026-09-16
Primary completion pushed: 2028-02-28 → 2028-06-28
Recruitment opened
Completion pushed: 2028-04-01 → 2028-12-01
NCT06796348 Radiofrequency Ablation Versus Hemithyroidectomy for Small Thyroid Cancers · University of Aarhus
2026-09-16
Primary completion pushed: 2026-10 → 2029-10
Completion pushed: 2026-10 → 2029-10
NCT04104529 Clinico-biological Database in Patients Treated With Metabolic Radiotherapy in the… · Institut du Cancer de Montpellier - Val d'Aurelle
2026-09-15
Primary completion pushed: 2026-07 → 2026-12
NCT04285476 Predictive Value of microRNA in Thyroid Cytologies of Undetermined Type · Institut du Cancer de Montpellier - Val d'Aurelle
2026-09-01
Primary completion pushed: 2027-06-01 → 2027-09-01
Trial status changed: Not Yet Recruiting → Active, Not Recruiting
Completion pushed: 2027-09-01 → 2027-12-01
NCT07485569 Drug Repurposing in Thyroid Carcinoma: a Feasibility Trial · Radboud University Medical Center · Phase 1
2026-09-02
Primary completion pushed: 2027-07 → 2028-07
Completion pushed: 2027-09 → 2028-09
NCT07690839 Pre-Clinic Visit Online Education for Thyroid Cancer · Cedars-Sinai Medical Center
2026-08-20
Primary completion pushed: 2025-12-31 → 2026-12-31
Primary endpoint(s) modified
Trial status changed: Enrolling by Invitation → Recruiting
Completion pushed: 2025-12-31 → 2026-12-31
NCT06931743 The Application of Electrical Stimulation in Postoperative Pain Management of Thyroid… · Xiaonan Huang
2026-08-19
Primary completion pushed: 2026-07-01 → 2026-12-01
Completion pushed: 2026-08-01 → 2027-01-01
NCT07428057 Postoperative Hypocalcemia After Thyroidectomy · Minia University
2026-09-03
Primary endpoint(s) modified
Trial completed
Primary completion confirmed: June 2026 (last estimated June 2027)
NCT05864144 A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in… · Sensei Biotherapeutics, Inc. · Phase 1/2
2026-09-10
Enrollment reduced: 12 → 9 participants
Sponsor changed: Stanford University → Saad A Khan
Results posted: 2026-09-09
Interventions modified
Completion pushed: 2026-09-01 → 2027-07
NCT05119296 Phase II Trial of Pembrolizumab in Metastatic or Locally Advanced… · Saad A Khan · Phase 2
2026-09-11
Enrollment closed, study ongoing
Final enrollment: 98 participants (planned 332)
NCT05557045 A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid… · Jazz Pharmaceuticals · Phase 1
2026-09-15
Enrollment closed, study ongoing
Final enrollment: 105 participants (planned 259)
NCT01660984 Natural History Study of Children and Adults With Medullary Thyroid Cancer · National Cancer Institute (NCI)
2026-08-19
Enrolling by invitation only
NCT07620574 Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored… · Exelixis · Phase 3
2026-09-05
Recruitment opened
NCT07459283 The Safety, Dosimetry and Efficacy of 177Lu-INN805 in Patients With Malignant Solid Tumors · FindCure Biosciences (ZhongShan) Co., Ltd. · Early Phase 1
2026-09-02
Enrollment closed, study ongoing
Trial sites reduced: 83 → 66 locations
Final enrollment: 148 participants (planned 124)
Completion moved earlier: 2029-06-18 → 2027-08-31
NCT05538130 A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in… · Pfizer · Phase 1
2026-09-02
Enrollment closed, study ongoing
Final enrollment: 103 participants (planned 267)
Primary completion moved earlier: 2028-04-23 → 2027-08-31
Completion moved earlier: 2029-10-25 → 2027-08-31
NCT05355701 A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced… · Pfizer · Phase 1
2026-08-22
Trial completed
NCT05241834 A Study of LOXO-260 in Cancer Patients With a Change in a Particular Gene (RET) That Has… · Eli Lilly and Company · Phase 1
2026-08-18
Recruitment opened
NCT07440290 DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult… · Cancer Research UK · Phase 2/3
2026-08-29
Trial completed
Study completion confirmed: July 2026 (last estimated August 2026)
NCT07524777 Ganoderma Spores Modulate the Gut-Brain Axis · Ling Zhiqiang

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-10 NCT07812779 Thyroid Health Outcomes Registry for Surgery Pirogov Russian National Research Medical University new
2026-08-20 NCT07776262 Safety and Efficacy of Cryoablation for Thyroid Tumors Yukun Luo new
2026-07-20 NCT07713901 Database Linkage Study to Evaluate the Risk of Medullary Thyroid Carcinoma Novo Nordisk new
2026-07-15 NCT07704658 Pralsetinib DDI Study in Patients With Advanced or Metastatic Solid Tumors Rigel Pharmaceuticals new Phase 4
2026-07-15 NCT07705074 FAPI PET Imaging - An Exploratory Study Martin Huellner new Phase 1/2
2026-07-10 NCT07695974 Clinicopathological Predictors of Recurrence in Papillary Thyroid Carcinoma University of Roma La Sapienza new
2026-07-08 NCT07690839 Pre-Clinic Visit Online Education for Thyroid Cancer Cedars-Sinai Medical Center new
2026-06-22 NCT07661420 211At-MABG in Adults With Advanced Neuroendocrine Cancers University of Pennsylvania new Phase 1
2026-06-22 NCT07659717 Frozen Section-Guided Selective Ipsilateral Central Neck Dissection in Bethesda V-VI… Eleonora Lori, MD new

Active trials by phase

Early Phase 1
6
Phase 1
25
Phase 1/2
11
Phase 2
62
Phase 2/3
5
Phase 3
16
Phase 4
7
Not charted: 188 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 320

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07704658 Pralsetinib DDI Study in Patients With Advanced or Metastatic Solid Tumors Rigel Pharmaceuticals Recruiting 2026-08-10
NCT07600580 The Association Between Bilateral Intermediate Cervical Plexus Block During Total… University Hospital Dubrava Recruiting 2026-06-16
NCT06195228 A Retrospective and Prospective Real-world Study of Molecular Typing in the Treatment of… Fudan University Recruiting 2025-08-14
NCT05830500 Study of Anlotinib in Patients With Advanced Medullary Thyroid Carcinoma Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Recruiting 2023-07-25
NCT07354698 Application of Mitoxantrone Hydrochloride Injection in Transoral Robotic Thyroid Cancer… Daping Hospital and the Research Institute of Surgery of the Third Military Medical University Not Yet Recruiting 2026-01-21
NCT01896479 A Study of Two Different Doses of Cabozantinib (XL184) in Progressive, Metastatic… Exelixis Active, Not Recruiting 2025-09-02
NCT07010393 Genotype-Driven Neoadjuvant Therapy for Locally Advanced Thyroid Cancer: A Real-World… Fujian Medical University Not Yet Recruiting 2025-06-08
Phase 3
NCT06475989 Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer ECOG-ACRIN Cancer Research Group Recruiting 2026-08-06
NCT04290663 Systematic Radioiodine Administration Versus Decision of Radioiodine Treatment Guided by… Centre Francois Baclesse Recruiting 2026-06-25
NCT06554652 Selective Neck Dissection Versus Modified Neck Dissection in PTC Fudan University Recruiting 2026-02-27
NCT06558981 Adjuvant Radiotherapy in High Risk Locally Advanced DTC Fudan University Recruiting 2026-02-27
NCT07383246 CTR-FAPI-guided Precision Surgery for Newly Diagnosed MTC Cancer Institute and Hospital, Chinese Academy of Medical Sciences Recruiting 2026-02-03
NCT06860971 A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced… Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Recruiting 2025-12-31
NCT05999630 Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With… Vanderbilt University Medical Center Recruiting 2025-10-28
NCT06791005 A Clinical Study on the Benefits of Carbon Nanoparticles Injection Time in Patients With… Second Affiliated Hospital of Xi'an Jiaotong University Recruiting 2025-01-24
NCT06082180 A Prospective, Open-label, Multicenter, Randomized Controlled Phase III Study of… Cancer Institute and Hospital, Chinese Academy of Medical Sciences Recruiting 2023-10-13
NCT07620574 Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored… Exelixis Enrolling by Invitation 2026-08-18
NCT04940052 Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously… Novartis Pharmaceuticals Active, Not Recruiting 2026-06-26
NCT04211337 A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid… Loxo Oncology, Inc. Active, Not Recruiting 2026-03-19
NCT03570021 ESTIMation of the ABiLity of Prophylactic Central Compartment Neck Dissection to Modify… Gustave Roussy, Cancer Campus, Grand Paris Active, Not Recruiting 2026-03-06
NCT07239674 Desiccated Thyroid Extract Combined With Levothyroxine for TSH Suppression Therapy in DTC West China Hospital Not Yet Recruiting 2025-11-20
NCT03690388 A Study of Cabozantinib Compared With Placebo in Subjects With Radioiodine-refractory… Exelixis Active, Not Recruiting 2025-09-25
NCT01837745 Differentiated Thyroid Cancer: is There a Need for Radioiodine Ablation in Low Risk… Gustave Roussy, Cancer Campus, Grand Paris Active, Not Recruiting 2023-05-17
Phase 2/3
NCT07440290 DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult… Cancer Research UK Recruiting 2026-08-17
NCT06851663 Trop2-targeted immunoPET Imaging of Solid Tumors RenJi Hospital Recruiting 2026-05-29
See all 320 active Thyroid Cancer trials with filters →

Top sponsors by active trials in this area

M.D. Anderson Cancer Center (17) · Memorial Sloan Kettering Cancer Center (14) · Fudan University (10) · National Cancer Institute (NCI) (10) · Fujian Medical University (7) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (6) · West China Hospital (6) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (5) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (5) · Assiut University (4)

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