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The Application of Electrical Stimulation in Postoperative Pain Management of Thyroid Surgery

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 12 months later Dec 31, 2025 → Dec 31, 2026
Primary endpoint removed 2 → 1 primary endpoints
See other at-risk trials from Xiaonan Huang

Record History

  1. Notable Primary and study completion pushed from Dec 31, 2025 to Dec 31, 2026 Primary endpoint(s) modified · Trial status changed: Enrolling by Invitation → Recruiting · Study sites: 1 to 3 · 2 morev2 Show 5 more changesShow less
    • Primary endpoint(s) modified
    • Trial status changed: Enrolling by Invitation → Recruiting
    • Study sites: 1 to 3
    • Secondary endpoints: 2 to 4
    • Study description shortened, about 168 words

    See this version in full on ClinicalTrials.gov ↗

  2. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
2 trials monitored
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387 trials monitored
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Post-thyroidectomy pain is a prevalent early postoperative complication. While pharmacological agents remain the mainstay of analgesia, their clinical application is constrained by adverse effects including nausea, respiratory depression, and gastrointestinal disturbances. Transcutaneous electrical nerve stimulation based on wrist-ankle acupuncture theory (TENS-WAA) is a non-invasive analgesic modality that has demonstrated preliminary benefits in multiple pain scenarios. Nevertheless, robust evidence for its efficacy in post-thyroidectomy pain management is still lacking, limited by single-center designs and small sample sizes in existing studies. This trial aims to evaluate the efficacy and safety of TENS-WAA for pain control after thyroidectomy. The findings are expected to support a standardized non-pharmacological analgesic option as an adjunct to multimodal postoperative pain regimens, aligning with Enhanced Recovery After Surgery (ERAS) principles.
Trial Details
NCT Number NCT06931743
Lead Sponsor Xiaonan Huang
Conditions Thyroid Surgery, Electrical Stimulation, Thyroid Carcinoma
Enrollment 668 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov